Term
| 2 classes of membrane proteins |
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Definition
transporters
channels- are faster |
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Term
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Definition
| have moving arts to transport specific molecules across membrane |
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Term
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Definition
| narrow hydrophyllic pores |
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Term
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Definition
downhill
solute flows through Chanel proteins |
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Term
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Definition
| pump against electrochemical gradient |
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Term
| 3 types of active transporters |
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Definition
coupled transporters
atp driven-
light driven- |
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Term
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Definition
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Term
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Definition
2 solutes same direction
2 solutes opposite direction |
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Term
| Na conc. is ___ extracellularly |
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Definition
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Term
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Definition
P-TYPE- phosphorylate themselves
- set and maintain gradient of Na, Ca, K,H
F TYPE-multiple subunits
- in plasma of bacteria and inner membrane of mito. & thylakoid
ABC TRANSPORTERS- pump small molecule (esp. in bacteria- both direction and eukaryotic-pump out of the cytosol) |
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Term
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Definition
P-TYPE ATPase
Ca- low in cytosol
high extracellularly |
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Term
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Definition
3 Na are pumped out
2K pumped in |
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Term
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Definition
conc. of solute less
water goes in cell- cell bursts |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| refractory period - 2 types |
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Definition
absolute- absolute nothing can change
channels are inactive
period of insensitivity
RELATIVE- if stimulus intensity increases we can get a response.
hyper polarization phase |
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Term
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Definition
- is integration of information
- how various stimulus can cometogether
-spatial and temporal |
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Term
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Definition
crosses the threshold
leads to an action potential |
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Term
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Definition
will not lead to cross the threshold
no action potential
slight change in membrane potential but returns |
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Term
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Definition
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Term
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Definition
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Term
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Definition
ACT. Potential is propogated
no mylenation |
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Term
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Definition
| convergent of many neurons/ blind spot |
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Term
| Na is a passive transport |
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Definition
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Term
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Definition
| active transport(going against coc. gradient) |
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Term
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Definition
lumen epithelium
glucose from lumen goes to ex. fluid
by Na glucose SYMPORTER
out of the cell by passive movement |
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Term
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Definition
prevents solutes from crossing the epithelium
serve as diffusion barriers |
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Term
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Definition
MECHANICALLY GATED- have cytoplasmic extension
LIGAND- extra. or intercell.
- some other molecule binds
VOLTAGE- dep. on membrane potential |
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Term
| ABC TRANSPORTER OF BACTERIA |
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Definition
78 GENES code for ABC trans. ~5% of e. coli genome
A-ATPase of ABC
B-binding protein
C- channel |
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Term
| multi drug resistance protein |
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Definition
is an ABC
kicks the drugs out
expressed in 40% of all cancer cells |
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