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Chapter 11
Nervous system
49
Anatomy
Undergraduate 2
11/08/2011

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Term
Sensory Input
Definition
information gathered by the nervous system
Term
Integration
Definition
nervous system processes and interprets sensory input and decides what should be done
Term
Motor Output
Definition
the nervous system’s response to the stimulus; done by activating effector organs (muscles and glands)
Term
astrocytes
Definition
most abundant and most versatile; make exchanges between capillaries and neurons, migration of young neurons and in synapse formation; control chemical environment around neurons; mop up leaked potassium ions and recapturing released neurotransmitters
Term
microglia
Definition
small ovoid cells with thorny processes; monitor the health of neurons; phagocytize microorganisms and neuronal debris
Term
ependymal cells
Definition
squamous or columnar cilitated cells that line the central cavities of the brains and spinal cord; the cilia helps to circulate cerebrospinal fluid
Term
oligodendyrocytes
Definition
line up along neuron fibers in the CNS and wrap their processed tightly; forms myelin sheaths
Term
satellite cells
Definition
surround neurons and cell bodies located in the PNS (same as astrocytes in CNS)
Term
Schwann cells
Definition
surround and form myelin sheaths around the larger nerve fibers of the PNS (similar to Oligodendrocytes)
Term
SPECIAL CHARACTERISTICS OF NERVE CELLS
Definition
1. Extreme longevity
2. Amitotic- can not divide and reproduce
3. High metabolic rate- require abundant supplies of oxygen and glucose
Term
Cell Body
Definition
also called the perikaryon or soma; major biosynthetic center of a neuron contains the following organelles:
Term
Clusters of cell bodies
Definition
CNS: nuclei
Term
Clusters of cell bodies
Definition
PNS: ganglia
Term
Bundles of neuron processes
Definition
CNS: tracts
Term
Bundles of neuron processes
Definition
PNS: nerves
Term
dendrites
Definition
main receptor or input regions; convey messages towards the cell body; graded potentials
Term
axon
Definition
conducting region or the neruron; generates nerve impulses and transmits them typically away from the cell body
Term
anterograde movement
Definition
movement toward the axon terminal; organelles and enzymes needed for synthesis of neurotransmitters
Term
retrograde movement
Definition
- movement away from the axon terminal; organelles being returned to the cell body for recycling and for intracellular communication
Term
Myelin Sheath and Neurilemma
Definition
protects and electrically insulates fibers; increases the speed of transmission of nerve impulses
Term
o Nodes of ranvier
Definition
gap in between parts of the myelin sheath
Term
white matter
Definition
regions of the brain containing dense collections of myelinated fibers; fiber tracts
Term
gray matter
Definition
contains mostly nerve cell bodies and unmyelinated fibers
Term
Structural classification of neurons
Definition
neurons are grouped according to the number of processes extending from their cell body
Term
multipolar neurons
Definition
have three or more processes; most common neuron in humans; major neuron type in the CNS
Term
bipolar neurons
Definition
have two processes; an axon and a dendrite; found in some of the special sensory organs such as the retina
Term
unipolar neurons
Definition
have a single short process that emerges from the cell body and divides t-like into proximal and distal branches
Term
functional classification of neurons
Definition
neurons are grouped according to the direction in which the nerve impulse travels relative to the CNS
Term
sensory neurons (afferent)
Definition
transmits impulses from sensory receptors in the skin or internal organs toward or into the CNS. All sensory neurons are unipolar and their cell bodies are located in sensory ganglia outside the CNS.
Term
motor neurons (efferent)
Definition
carry impulses away from the CNS to the effector organs (muscles and glands) of the body periphery. Motor neurons are multipolar; located in the CNS.
Term
Interneurons
Definition
lie between motor and sensory neurons and shuttle signals through CNS pathways where intergration occurs; make up 99% of all the neurons of the body; including most of those in the CNS; multipolar
Term
voltage
Definition
the measure of potential energy generated by separated charge
Term
current
Definition
the flow of electrical charge from one point to another
Term
resistance
Definition
is the hindrance to charge flow provided by substances through which the current must pass
Term
high resistance
Definition
insulators
Term
low resistance
Definition
conductors
Term
OHM’S LAW
Definition
Current (I)= voltage (v)/resistance (R)
Term
Leakage or nongated channels
Definition
always open
Term
Chemically gated or ligand-gated channels
Definition
open when the appropriate chemical (neurotransmitter) binds
Term
voltage gated channels
Definition
open and close in response to changes in the membrane potential
Term
mechanically gated channels
Definition
open in response to physical deformation of the receptor
Term
electrochemical gradient
Definition
electrical and concentration gradient together; Ion flow along electrochemical gradients underlies all electrical phenomenon in neurons
Term
RESTING MEMBRANE POTENTIAL
Definition
a difference in K+ and Na+ concentrations inside and outside cells; differences in permeability of the plasma membrane of these ions
Term
depolarization
Definition
a reduction in the membrane potential: the inside of the membrane becomes less negative or moves closer to zero
Term
hyperpolarization
Definition
- occurs when the membrane potential becomes more negative
Term
graded potentials
Definition
are short lived localized changes in membrane potential; can be either depolarization or hyperpolarization
Term
action potentials
Definition
- a brief reversal of membrane potential with a total amplitude change of about 100 mV; a depolarization phase is followed by a repolarization phase and often a short period of hyperpolarization; an influx of Na+ leaves for a temporary positive charge in axon
Term
Absolute refractory period
Definition
the period from the opening of the Na+ channels until the Na+ channels begin to reset to their original resting state
Term
relative refractory period
Definition
the interval following the absolute refractory period; repolarization is occurring
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