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Fluid that fills the space b/w cells (extracellular) |
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Fluid found in blood vessels |
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There is equal osmotic pressure to the contents of a cell -a cell in an isotonic solution neither gains nor loses water |
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A solution that contains enough solute that it will draw water out of a cell placed in it |
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A solution that contains so little solute that a cell placed in it will absorb water |
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Reduction in the volume of the intravascular fluid -heart can't pump blood effectively=heart failure |
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Cellular dehydration caused by an increase in the osmotic pressure of the interstitial fluid -drives organism to drink |
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Neurons that detect changes in solute concentration -changes in size causes changes in activity -in the hypothalamus (SFO and OVLT)- detect increased osmotic pressure |
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Caused by hypovolemia -occurs when volume of the blood plasma decreases -caused by loss of blood, vomiting, etc. -results in thirst for water and a "salt appetite" |
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Volumetric thirst is caused by 2 sets of receptors that are located where? |
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Definition
-Kidneys (control angiotension) -Heart and large blood vessels (atrial baroreceptors) |
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Definition
A hormone that constricts blood vessels and causes retention of sodium and water (salt appetite) |
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Hormone secreted by kidneys -converts angiotensinogen into angiotensin |
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Stretch receptors in the atria of the heart -more blood = more stretched |
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What is stored in short term-storage and where? |
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Definition
Carbohydrates -liver and muscles |
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What is stored in long-term storage and where? |
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Definition
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Hormone in pancreas that lets glucose and amino acids into the cell -converts glucose into glycogen |
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Short-term storage of nutrients -stored in liver and muscle |
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Hormone that converts glygogen back into glucose |
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The form of fat storage in adipose cells -1 molecule of glycerol + 3 fatty acids |
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Made when breaking down triglycerides -liver converts it into glucose |
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Made when triglycerides are broken down -Metabolized by most cells of the body except for the brain |
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Definition
The phase of metabolism when nutrients are not available from the digestive system -glucose, amino acids, and fatty acids are derived during this phase |
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The phase of metabolism when nutrients are absorbed from the digestive system -glucose and amino acids are the main source of energy for cells during this phase -excess nutrients are stored in adipose tissue in the form of triglycerides |
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Definition
A fall in the level of glucose available to cells -can be caused by hypoglycemia or injection of insulin |
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A fall in the level of fatty acids available to cells -caused by drugs that inhibit fatty acid metabolism |
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Where are the 2 sets of detectors located for monitoring level of metabolism? |
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Definition
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Definition
The vein that transports blood from the digestive system to the liver |
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Term
What gastric factor is involved in ending a meal? |
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Definition
Stomach -contains receptors that detect the presence of nutrients (not just distention) |
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What 2 intestinal factors are involved in ending a meal? |
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Definition
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Definition
First part of the small intestine, attached to the stomach -secretes CCK: a hormone that provides a satiety signal to the brain |
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Definition
A peptide released by the gastrointestinal system after a meal in an amount proportional to the size of a meal |
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What liver factor is involved in ending a meal? |
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Definition
Receptors that detect nutrients and send signals to your brain |
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What role does insulin have in the absorption phase of metabolism? |
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Definition
The brain contains receptors that respond to insulin -might be a satiety signal (obese mice) |
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Definition
A hormone secreted by adipose tissue -decreases food intake -increases metabolic rate |
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Definition
A strain of mice whose obesity is caused by a lack of the production of leptin |
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Term
If you lesion/stimulate the lateral hypothalamus (LH), what would happen? |
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Definition
Lesion: won't eat Stimulate: eat |
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Term
Melanin-concentrating hormone (MCH) |
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Definition
NT found in the LH that stimulates appetite and reduces metabolic rate |
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Definition
NT found in the LH that stimulates appetite and reduces metabolic rate |
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Definition
NT found in the arcuate nucleus that: -stimulates feeding -stimulates insulin secretion -decreases breakdown of triglycerides -decreases body temperature |
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Infusions of NPY into the hypothalamus do what? |
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Definition
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Injections of NPY receptor blockers into the hypothalamus do what? |
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Definition
Suppresses eating caused by food deprivation |
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Term
Agouti-related peptide (AGRP) |
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Definition
A peptide that is a strong and long-lasting stimulant of eating |
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Definition
A peptide that increases eating -in stomach and brain |
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Definition
Contains NPY-secreting neurons involved in feeding and control of metabolism -controls the anterior pituitary gland -located in the hypothalamus |
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Paraventricular nucleus (PVN) |
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Definition
Contains neurons involved in the control of the: -autonomic nervous system -posterior pituitary gland
-located in the hypothalamus |
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Ventromedial hypothalamus |
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Definition
Plays a role in controlling the cessation of eating |
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