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Chapter 10
Structure and Functions of DNA
39
Biology
Undergraduate 2
11/15/2011

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Term
Mutation
Definition
Any change in the nucleotide sequence of DNA
Term
Base Substitution
Definition
Substitute an A For a G which changes the results in the polypeptide
Term
Nucleotide Deletion
Definition
When nucleotides are deleted, and the resulting polypeptide is likely to be completely nonfunctional
Term
Necleotide Insertion
Definition
Inserting one nucleotide disrupts all codons that follow, most likely producing a nonfunctional polypeptide
Term
Silent Mutation
Definition
A change that doesn't result in a significant change.
Term
Missense Mutations
Definition
Other changes of a single nucleotide do change the amino acid coding
Term
Nonsense Mutation
Definition
The changing of an amino acid codon into a stop codon
Term
Molecular Biology
Definition
The study of heredity at the molecular level
Term
Nucleotides
Definition
Long chains of chemical units
Term
Polynucleotide
Definition
A polymer made up of many nucleotides covalently bonded together
Term
Sugar-phospate backbone
Definition
A repeating pattern of sugar-phospate
Term
Thymine (T)
Definition
A nitrogenous base that is a single-ring structure found in DNA
Term
Cytosine (C)
Definition
A nitrogenous base that is a single-ring structure found in DNA
Term
Adenine (A)
Definition
A nitrogenous base that is a larger double-ring structure found in DNA
Term
Guanine (G)
Definition
A nitrogenous base that is a larger double-ring structure found in DNA
Term
Uracil (U)
Definition
A single ringed nitrogeneous base found in RNA
Term
Double Helix
Definition
The shape of DNA (James Watson and Francis Crick discovered this)
Term
DNA Polymerases
Definition
The enzymes that make the covalent bond berween nucleotides of a new DNA strand
Term
DNA Replication
Definition
Replication resultsin two daughter DNA molecules, each consisting of one old strand and one new strand. The parental DNA untwists as its strands seperate, and the daughter DNA rewinds as it forms.
Term
Phenotype
Definition
The organism's physical traits
Term
Genotype
Definition
The organism's genetic make-up
Term
Transcription
Definition
The transfer of genetic informationfrom DNA into an RNA molecule
Term
Translation
Definition
The transfer of the information from RNA into a protien
Term
Codons
Definition
A series of three-base words: where the instructions for the amino acid sequences of a polypeptide chain and written in DNA and RNA.
Term
Genetic Code
Definition
The set of rules relating nucleotide sequences to amino acid sequences
Term
RNA Polymerase
Definition
The transcription enzyme which links the RNA nucleotides
Term
Promoter
Definition
The "start transcribing" signal in a nucleotide sequence
Term
Initiation
Definition
The first phase of Transcripstion: it's the attachment of RNA polymerase to the promoter and the start of RNA synthesis
Term
Elongation
Definition
The scecond phase of Transcription:the RNA grows longer and as RNA synthesis continues the RNA strand peels away from its DNA template
Term
Termination
Definition
The third phase of Transcription:is a special sequence of bases in the DNA template which signals the end of the gene.
Term
Messanger RNA (mRNA)
Definition
The messanger molecule that is translated
Term
Virus
Definition
"genes in a box" a bit of nucleic acid wrapped in a protien coat
Term
Bacteriophages
Definition
Viruses that attack bacteria
Term
Phages
Definition
Short term fore Bacteriophages
Term
Retrovirus
Definition
An RNA virus that reproduces by means of a DNA molecule
Term
Reverse Transcription
Definition
Enzymes which catalyzes reverse transcription, the synthesis of DNA and RNA template.
Term
Viroids
Definition
Small circular RNA molecules that infect plants
Term
Prions
Definition
Infection protiens
Term
Emerging Viruses
Definition
Viruses that have appeared suddenly or have recently come to the attetnion of medical scientist
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