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Two types of data collection |
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Definition
randomized experiment and observational study |
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Randomized experiments can prove |
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randomized controlled double-blind experiment |
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Portacaval shunt studies (liver surgery) |
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assignment to control group was not randomized |
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Term
Did the the four therapy studies use historical controls |
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What are historical controls |
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Definition
patients treated the old way in the past |
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Trials with historical controls are |
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randomized controlled experiments are good and minimize what |
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a third variable associated with exposure to disease (confusing factors) |
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observational studies establish what |
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Definition
association, and can be misleading |
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which type of study is best: observational or randomized experiment |
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Definition
randomized controlled experiment |
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observational study: Clofibrate trial (coronary drug project) |
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randomized control double blind experiment- some patients didn’t take the medications to lower cholesterol |
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Definition
association is not causastion |
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Definition
presence of confounding factors (sexually transmitted disease) |
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Ultrasound and low birth rate |
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only an observational study |
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Term
Treatment Group is given the |
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Control Group is given the |
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What does comparing these two groups mean? |
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Definition
The difference in the response is due to the treatment |
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Term
Why is a placebo neutral and why should it resemble the treatment |
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Definition
the response should be due to the treatment itself rather than the idea of the treatment |
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Definition
neither the investigator or the subject know who is the treatment group and who is the control group |
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Term
Does the investigator or the subject have the power to assign subjects in an observational study |
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one thing linked to another |
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on overall outcome due to something for example exposure to disease |
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How good is observational studies |
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The weakness of observational studies is |
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