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The cell is the smallest structural and functional living unit |
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Biochemical activities of cells are dictated by: |
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their specific subcellular structures |
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Human cells have three basic regions: |
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Plasma membrane—flexible outer boundary Cytoplasm—intracellular fluid containing organelles Nucleus—control center |
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Plants have cell: Animals have cell: |
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walls; membranes (flexible) |
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Membrane Lipids: Composition & anatomy |
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75% phospholipids (lipid bilayer) Phosphate heads: polar and hydrophilic Fatty acid tails: nonpolar and hydrophobic 20% cholesterol Increases membrane stability and fluidity 5% glycolipids Lipids with polar sugar groups on outer membrane surface |
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Membrane Junctions; Three types: |
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Tight junction Passage between cells ECF Desmosome Anchor cells together “rivits” Gap junction Allows passage of ions between cells |
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Located between plasma membrane and nucleus |
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Water with solutes (protein, salts, sugars, etc.) |
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Metabolic machinery of cell |
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Granules of glycogen or pigments, lipid droplets, vacuoles, and crystals |
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Provide most of cell’s ATP via aerobic cellular respiration -Power House Contain their own DNA and RNA |
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Endoplasmic Reticulum (ER) |
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Interconnected tubes and parallel membranes enclosing cisternae Continuous with nuclear membrane |
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Manufactures all proteins Studded with ribosomes (red dots) Synthesizes membrane integral proteins and phospholipids |
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Enzymes and more lipid based proteins: depends on the organ In the liver —lipid and cholesterol metabolism, breakdown of glycogen, along with kidneys, detoxification of drugs, pesticides, and carcinogens Endocrine glands-Synthesis of steroid-based hormones In intestinal cells—absorption, synthesis and transport of fats In muscle—storage and release of calcium |
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protein synthesis Free ribosomes synthesize soluble proteins Membrane-bound ribosomes insoluble-- membrane bound proteins |
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Modifies, concentrates, and packages proteins and lipids (packaging plant) Secretes vesicles that pinch off from the Golgi stack and move to designated parts of cell |
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Clean up crew; Vesicles containing digestive enzymes Digest bacteria, viruses, and toxins Degrade nonfunctional organelles Break down and release glycogen Destroy injured or nonuseful cells (autolysis) |
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Clean up Crew; Sacs containing powerful oxidases and catalases Detoxify harmful or toxic substances Neutralize dangerous free radicals |
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include: the nuclear envelope, the endoplasmic reticulum, the Golgi apparatus, lysosomes, vacuoles, vesicles, and the cell membrane. Produce, store, and export biological molecules Degrade potentially harmful substances |
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bones of the cell; Microfilaments Intermediate filaments
Dynamic strands attached to cytoplasmic side of plasma membrane Involved in cell motility, change in shape, endocytosis and exocytosis |
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A region near the nucleus that contain paired organelles called 'centrioles' Generates microtubules; organizes mitotic spindle Contains centrioles: Small tube formed by microtubules Mitosis Director |
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Cilia and flagella Whiplike, motile extensions on surfaces of certain cells Contain microtubules and motor molecules Cilia move substances across cell surfaces Longer flagella propel whole cells (tail of sperm) |
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the extracellular part of animal tissue that usually provides structural support to the animal cells in addition to performing various other important functions. |
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all body fluid outside of cells. The remainder is called intracellular fluid. |
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Genetic blueprint for cellular proteins Responds to signals and dictates kinds and amounts of proteins to be synthesized |
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a very important part of centrosomes, which are involved in organizing microtubules and the mitotic spindle (cell division) in the cytoplasm. |
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