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He discovered that a transforming factor could be transferred into a bacterial cell |
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Disease causing bacteria (were killed by heat) |
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Harmless bacteria (were incubated with heat killed bacteria) |
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When harmless cells were converted to disease causing bacteria |
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Alfred Hershey and Martha Chase |
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Used bacteriophages to show DNA is the genetic material |
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Viruses that infect bacterial cells |
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Monomer unit of DNA and Rna |
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It's the nucleotide and it contains a nitrogenous base, a 5-carbon sugar, and a phosphate group. |
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Formed by covalent bonding between the phosphate of one nucleotide and the sugar of the next nucleotide |
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James D. Watson and Francis Crick |
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Deduced the seondary structure of DNA, with x-ray crystalllography data from Rosalind Franklin and Maura Wilkins |
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Composed of two polynucleotide chains joined together by hydrogen bonding between bases, twisted in helical shape. |
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-Two strands separate -each strand is used to pattern a complementary strand, using specific base pairing -each new DNA has a new strand and an old strand
It begins at origin. -Unwinds at origin to produce bubble -Replication proceeds in both directions from the origin -Replication ends when product from bubbles merge with each other |
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Proteins involved in DNA Replication |
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-DNA plymerase adds nucleotide to growing chain -DNA ligase joins small fragments into a continuous chain |
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DNA separates, RNA uses specific base pairing, RNA polymerase catalyzes the reaction |
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Initiation: RNA polymerase binds to a promoter Elongation: RNA nucleotides are added to the chain Termination: RNA plymerase reaches a terminator sequence and detaches from template. |
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Codons for protein sequence |
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Molecules match an amino acid to its corresponding mRNA codon. |
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Allows tRNA to bind to a specific mRNA codon, complementary in sequence. |
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