Term
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Definition
GI, bradycardia, bronchospasm |
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Term
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Definition
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Term
SNRIs, fluoxetine, sertraline, paroxetine |
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Definition
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Term
sertraline and citalopram |
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Definition
preferred SSRIs in elderly |
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Term
low dose SSRI (citalopram 5 mg) |
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Definition
reduce fall risk and avoid GI effects |
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Term
QTc interval prolongation |
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Definition
citalopram max dose of 20 mg/day in >60 year old |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
useful for depression, inducing sleep, appetite stimulation |
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Term
more drowsiness at lower doses (7.5-15mg) |
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Definition
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Term
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Definition
greater effect at higher doses |
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Term
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Definition
strong H1 blocker but low anticholinergic |
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Term
BPSD more acute situations |
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Definition
aggressiveness threat to oneself or others; hallucinations with distress |
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Term
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Definition
may be useful in more mild cases or sensitive patients |
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Term
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Definition
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Term
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Definition
avoids orthostatic hypotension (25-50mg) |
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Term
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Definition
anti-convulsants (carbamazepine) |
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Term
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Definition
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Term
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Definition
may accelerate brain damage in dementia (evidence does not support use in aggressive BPSD) |
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Term
benzos generally not recommended |
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Definition
may be effective for anxiousness/ lack of sleep |
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Term
paradoxical response can be caused by |
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Definition
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Term
benzos of choice for BPSD |
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Definition
lorazepam, temazepam and oxazepam |
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Term
long-acting benzos with active metabolites |
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Definition
diazepam, flurazepam, chlorazepate (avoid use in dementia patients) |
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Term
danger from the hallucinations |
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Definition
anti-psychotics are most effective |
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Term
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Definition
carry a black box warning in dementia patients; increased risk of death |
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Term
when should anti-psychotics be used |
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Definition
only if patient is at risk of harming his/herself or others |
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Term
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Definition
try other meds first, check for appropriate dose, monitor carefully for CNS depression |
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Term
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Definition
strongest evidence dementia overall, psychosis and agitation |
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Term
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Definition
may worsen psychosis in some patients, ok data for agitation |
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Term
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Definition
may help more in areas other than psychosis or agitation, not generally used in dementia patients |
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Term
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Definition
lacks evidence , no benefit for agitation/ psychosis in dementia over placebo |
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Term
2nd generation (atypicals) |
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Definition
have a broader effect on additional neurotransmitters (besides dopamine) |
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Term
1st generation (typicals) |
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Definition
haloperidol, only good for aggression |
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Term
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Definition
not common in eldery (wandering worse, looks like agitation); SE of antiphych |
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Term
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Definition
parkinsonism, dystonia, akathisia and tardive dyskinesia |
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