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ch. 9
The Cell Cycle and Cellular Reproducion
44
Biology
Undergraduate 1
06/27/2012

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Term
anaphase
Definition
Mitotic phase during which daughter chromosomes move toward the poles of the spindle.
Term
angiogenesis
Definition
Formation of new blood vessels; one mechanism by which cancer spreads.
Term
apoptosis
Definition
Programmed cell death involving a cascade of specific cellular events leading to death and destruction of the cell.
Term
asexual reproduction
Definition
Reproduction that requires only one parent and does not involve gametes.
Term
aster
Definition
Reproduction that requires only one parent and does not involve gametes.
Term
benign
Definition
Mass of cells derived from a single mutated cell that has repeatedly undergone cell division but has remained at the site of origin.
Term
binary fission
Definition
Splitting of a parent cell into two daughter cells; serves as an asexual form of reproduction in bacteria.
Term
cancer
Definition
Malignant tumor whose nondifferentiated cells exhibit loss of contact inhibition, uncontrolled growth, and the ability to invade tissue and metastasize.
Term
caspase
Definition
Cell cycle regulatory enzyme that initiates apoptosis.
Term
cell cycle
Definition
Repeating sequence of events in eukaryotes that involves cell growth and nuclear division; consists of the stages G1, S, G2, and M.
Term
cell plate
Definition
Structure across a dividing plant cell that signals the location of new plasma membranes and cell walls.
Term
centriole
Definition
Cell organelle, existing in pairs, that occurs in the centrosome and may help organize a mitotic spindle for chromosome movement during animal cell division.
Term
centromere
Definition
Constriction where sister chromatids of a chromosome are held together.
Term
centrosome
Definition
Central microtubule organizing center of cells. In animal cells, it contains two centrioles.
Term
chromatid
Definition
Following replication a chromosome consists of a pair of sister chromatids, each a single DNA helix, held together at the centromere. Following separation, each chromosome is a single chromatid.
Term
chromatin
Definition
Network of DNA strands and associated proteins observed within a nucleus that is not dividing.
Term
cyclin
Definition
Protein that cycles in quantity as the cell cycle progresses; combines with and activates the kinases that function to promote the events of the cycle.
Term
cytokinesis
Definition
Division of the cytoplasm following mitosis or meiosis.
Term
diploid (2n) number
Definition
Cell condition in which two of each type of chromosome are present.
Term
growth factor
Definition
A hormone or chemical, secreted by one cell, that may stimulate or inhibit growth of another cell or cells.
Term
haploid (n) number
Definition
Cell condition in which only one of each type of chromosome is present.
Term
histone
Definition
A group of proteins involved in forming the nucleosome structure of eukaryote chromatin.
Term
interphase
Definition
Stages of the cell cycle (G1, S, G2) during which growth and DNA synthesis occur when the nucleus is not actively dividing.
Term
karyokinesis
Definition
Division of the nucleus.
Term
kinetochore
Definition
An assembly of proteins that attaches to the centromere of a chromosome during mitosis.
Term
malignant
Definition
The power to threaten life; cancerous.
Term
metaphase
Definition
Mitotic phase during which chromosomes are aligned at the metaphase plate.
Term
metaphase plate
Definition
A disk formed during metaphase in which all of a cell's chromosomes lie in a single plane at right angles to the spindle fibers.
Term
metastasis
Definition
Spread of cancer from the place of origin throughout the body; caused by the ability of cancer cells to migrate and invade tissues.
Term
mitosis
Definition
Process in which a parent nucleus produces two daughter nuclei, each having the same number and kinds of chromosomes as the parent nucleus.
Term
mitotic spindle
Definition
Microtubule structure that brings about chromosomal movement during nuclear division.
Term
Nucleoid
Definition
Region of prokaryotic cells where DNA is located; it is not bounded by a nuclear envelope.
Term
oncogene
Definition
Cancer-causing gene. Oncogenes code for proteins that stimulate the cell cycle and inhibit apoptosis.
Term
prometaphase
Definition
Phase of mitosis during which the chromosomes are condensed but not fully aligned at the metaphase plate.
Term
prophase
Definition
Mitotic phase during which chromatin condenses so that chromosomes appear; chromosomes are scattered.
Term
proto-oncogene
Definition
Normal gene that can become an oncogene through mutation.
Term
RB
Definition
Tumor suppressor genes whose protein interprets growth signals and nutrient availability before allowing the cell cycle to proceed.
Term
signal
Definition
Molecule that stimulates or inhibits an event in the cell cycle.
Term
somatic cell
Definition
Body cell; excludes cells that undergo meiosis and become sperm or egg.
Term
telomere
Definition
Tip of the end of a chromosome that shortens with each cell division and may thereby regulate the number of times a cell can divide.
Term
telophase
Definition
Mitotic phase during which daughter cells are located at each pole.
Term
therapeutic cloning
Definition
Used to create mature cells of various cell types. Also, used to learn about specialization of cells and provide cells and tissue to treat human illnesses.
Term
tumor
Definition
Cells derived from a single mutated cell that has repeatedly undergone cell division; benign tumors remain at the site of origin, while malignant tumors metastasize.
Term
tumor suppressor gene
Definition
Gene that codes for a protein that ordinarily suppresses the cell cycle; inactivity due to a mutation can lead to a tumor.
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