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Ch5 The Structure and Function of Macromolecules
BIO181 BIO 181 Obermiller
104
Biology
Undergraduate 2
06/10/2012

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Term
Formed by two fatty acids bound to one glycerol (containing a phosphate group).
Definition
Phospholipid
Term
Branched glucose polymer found in animals. Linked by Alpha 1-4 and Alpha 4-6 bonds.
Definition
Glycogen
Term
Lipids composed of four fused carbon rings.
Definition
Steroid
Term
The type of base found in nucleotides.
Definition
Nitrogenous
Term
Unbranched glucose polymer found in plants. Linked by Alpha 1-4 bonds.
Definition
Amylose
Term
Unbranched D-glucose polymer found in plants. Linked by Beta 1-4 bonds.
Definition
Cellulose
Term
Polymers of sugars.
Definition
Polysaccharides
Term
Type of fatty acid that contains no double carbon bonds.
Definition
Saturated
Term
Type of reaction that involves the addition of water. Used to break monomers.
Definition
Hydrolysis
Term
Polysaccharide that is a polymer of an amino sugar.
Definition
Chitin
Term
Three fatty acids bound to one glycerol.
Definition
Triglyceride
Term
Type of nucleotide whose nitrogenous base is made of a single ring.
Definition
Pyrimidine
Term
The most common sugar used for energy in cells.
Definition
Glucose
Term
Type of bond that links nucleotides together.
Definition
Phosphodiester
Term
Building blocks (monomers) of proteins.
Definition
Amino Acids
Term
Organic molecules made of sugars.
Definition
Carbohydrates
Term
The type of sugar found in nucleotides.
Definition
Ribose
Term
Type of nucleotide whose nitrogenous base is made of a double ring.
Definition
Purine
Term
Chains (polymers) of amino acids
Definition
Polypeptide
Term
Type of bond that links sugars together.
Definition
Glycosidic
Term
Linkage formed in fats between the fatty acid tail and glycerol.
Definition
Ester
Term
Type of reaction that involves the removal of water. Used to join monomers.
Definition
Dehydrated
Term
Large molecules containing repeating sub-units covalently linked together.
Definition
Polymers
Term
Formed by one or more polypeptide chains.
Definition
Proteins
Term
What are the four main types of macromolecules?
Definition
Carbohydrates
Lipids
Proteins
Nucleic Acids
Term
What type of reactions are used to make or break the polymers?
Definition
Condensation reaction (dehydration) is used to make polymers.

Hydrolysis reaction is used to break polymers.
Term
What causes polymers to link during the condensation reaction?
Definition
Removing water
Term
What causes polymers to split during the hydrolysis reaction?
Definition
Adding water
Term
Name the four types of polysaccharides.
Definition
Starch
Glycogen
Cellulose
Chitin
Term
In what type of organism is starch likely to be found?
Definition
Plants
Term
In what type of organism is glycogen likely to be found?
Definition
Animals
Term
In what type of organism is cellulose likely to be found?
Definition
Plants
Term
In what type of organism is chitin likely to be found?
Definition
In the exoskeletons of arthropods (including insects, spiders, and crustaceans)
Term
How many Carbons are in a triose?
Definition
Three
Term
How many Carbons are in a pentose?
Definition
Five
Term
How many Carbons are in a hexose?
Definition
Six
Term
Are lipids hydrophilic or hydrophobic?
Definition
Lipids are hydrophobic because their structures are dominated by nonpolar covalent bonds making them insoluble in water.
Term
What are the principal components of a triglyceride?
Definition
3 fatty acids bonded to 1 glycerol
Term
What monomers are contained in starch?
Definition
Term
What monomers are contained in glycogen?
Definition
Term
What monomers are contained in cellulose?
Definition
Term
What monomers are contained in chitin?
Definition
Term
What type of glycosidic linkages are in starch?
Definition
Alpha 1-4
Term
What type of glycosidic linkages are in glycogen?
Definition
Alpha 1-4 and Alpha 1-6
Term
What type of glycosidic linkages are in cellulose?
Definition
Beta 1-4
Term
What type of glycosidic linkages are in chitin?
Definition
Beta 1-4
Term
What are some functions of carbohydrates?
Definition
Serve as fuel and a carbon source
Term
What are some functions of lipids?
Definition
1. Long term fuel storage in adipose (fat) cells
2. Cushion for vital organs
3. Insulation against heat loss (whale blubber)
Term
What are some functions of proteins?
Definition
1. Structural support (keratin)
2. Storage of AA (albumin)
3. Transport (hemoglobin)
4. Signaling (insulin)
5. Stimuli (receptors)
6. Movement (myosin)
7. Immune (antibody)
8. Enzyme (catalyst)
Term
What are some functions of nucleic acid?
Definition
DNA
RNA
Term
What is a micelle?
Definition
The structure made by phospholipids when they are added to water.

They self-assemble into aggregates with the hydrophobic tails pointing toward the center and the hydrophilic heads on the outside.
Term
What is the precursor to all steroids?
Definition
Cholesterol
Term
What are the principal components of a phospholipid?
Definition
Glycerol, 2 fatty acids, and a phosphate group on carbon number 3
Term
What are the principal components of a steroid?
Definition
Skeleton carbon consisting of four carbon rings with varying functional groups
Term
Describe characteristics of saturated fats.
Definition
-No double bonds
-Maximum number of hydrogens
-Solid at room temp
-Mostly animal fats
-Straight chains
Term
Describe characteristics of unsaturated fats.
Definition
-One+ double bonds between carbons
-Liquid at room temp
-Mostly plant fats
-Tail "kinked" at double bond
Term
In what organism are saturated fats likely to be found?
Definition
Animals
Term
In what organism are unsaturated fats likely to be found?
Definition
Plants
Term
Are saturated or unsaturated fats liquid at room temp?
Definition
Unsaturated fats
Term
Name the four main types of macromolecules.
Definition
Carbohydrates
Lipids
Proteins
Nucleic Acids
Term
Why is protein conformation important?
Definition
The shape that the protein folds into determines the function of the protein
Term
What are the four levels of protein conformation?
Definition
-Primary
-Secondary
-Tertiary
-Quarternary
Term
What are primary structures?
Definition
Linear sequence of Amino Acids

Determined by genes (DNA sequence)
Term
What are secondary structures?
Definition
Formed by regular intervals of hydrogen bonds along backbone

Coiling/Folding

2 structures:
-Alpha Helix (coil)
-Beta Sheet (fold)
Term
What are tertiary structures?
Definition
3D shape of the protein

Determined by interactions with R groups:
-hydrogen bonds
-ionic bonds
-hydrophobic interactions
-disulfide bridges
Term
What are quarternary structures?
Definition
Structures formed by two or more polypeptide subunits
Term
Give examples of quarternary structures.
Definition
Collagen
Hemoglobin
Term
Which protein structure is most dependent on R group interactions?
Definition
Tertiary Structure
Term
Which secondary structure has a sheet shape?
Definition
Beta Sheets
Term
Which secondary structure has a coil shape?
Definition
Alpha Helix
Term
Which secondary structure has the most H bonds?
Definition
Beta Sheets
Term
What are two types of nucleic acids?
Definition
DNA
RNA
Term
What is the molecular difference between DNA and RNA?
Definition
Sugar in DNA is deoxyribose; while sugar in RNA is ribose.

Bases in DNA are AGTC
Bases in RNA are AGUC
Term
Does condensation and hydrolysis reactions occur by themselves or with the help of enzymes?
Definition

Condensation requires energy and is aided by enzymes.

 

Hydrolysis is guided by specific enzymes.

Term
What is the name of the bond formed by condensation?
Definition
Covalent bond
Term
What is the name of the bond formed by hydrolysis?
Definition
Term
What is the difference between ketose and aldose?
Definition

If the carbonyl group is in the middle, its a ketose.

 

If the carbonyl group is at the end, its an aldose.

Term
Give an example of aldose.
Definition
Glucose
Term
Give an example of ketose.
Definition
Fructose
Term
What are the monomers of proteins?
Definition
Amino Acids
Term
How many different types of Amino Acids are there?
Definition
Twenty
Term
What are the four groups found on each monomer?
Definition

Hydrogen

Amino

Carboxyl

"R" group

Term
What is the function of DNA?
Definition
  1. Contains coded information (on genes) that programs all cell activity.
  2. Not directly involved in the day to day operations of the cell.
  3. Contains the directions for its own replication.
Term
What is the function of RNA?
Definition
Involved in the actual synthesis of proteins encoded in DNA
Term
What are the three types of RNA?
Definition
  1. mRNA - messenger RNA
  2. tRNA - transfer RNA
  3. rRNA - ribosomal RNA
Term
What is the function of mRNA?
Definition
Carries encoded genetic messages (from DNA)
Term
What is the function of tRNA?
Definition
Transfers the Amino Acids to a forming protein.
Term
What is the function of rRNA?
Definition
Involved in the actual synthesis of proteins (ribosome)
Term
What is the central dogma of molecular biology?
Definition

DNA is made into mRNA

mRNA is made into Protein

Term
Name the four nucleotides in DNA.
Definition

A = Adenine

T = Thymine

C = Cytosine

G = Guanine

Term
Name the four nucleotides in RNA.
Definition

A = Adenine

U = Uracil

C = Cytosine

G = Guanine

Term
Which nucleotides pair with each other in DNA?
Definition

A-T

C-G

Term
Which nucleotides pair with each other in RNA?
Definition

A-U

C-G

Term
How many hydrogen bonds does each pair form?
Definition

2 Hydrogen Bonds A-T

3 Hydrogen Bonds C-G

Term
What is the structure (three parts) of a nucleotide?
Definition

Carbon Sugar

Phosphate Group

Nitrogenous Bases

Term

If a new organism was found that has 68 differences in amino acids in hemoglobin than humans, 55 from gibbon, 60 from mouse, and 8 from frog, which animal would you assume it is most closely related to?

 

Definition
The new organism is most closely related to the frog.
Term
What are the monomers of carbohydrates?
Definition
Monosaccaride
Term
What are the monomers of lipids?
Definition
Fatty Acids
Term
What are the monomers of Nucleic Acids?
Definition
Nucleotides
Term
[image]
Definition
Monosaccharide
Term
[image]
Definition
Amino Acid
Term
[image]
Definition
Fatty Acid
Term
[image]
Definition
Nucleotide
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