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Ch3 cells
test 2
104
Biology
Undergraduate 3
09/16/2012

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Term
reproductive (sex) cells
includes the male and female gametes and their developmental precursors
male: spermatazoan
female: ovum
Definition
Germline cells
Term
Germline cells
reproductive (sex) cells
includes the male and female gametes and their developmental precursors
male: ???
female: ovum
Definition
spermatazoan
Term
Germline cells
reproductive (sex) cells
includes the male and female gametes and their developmental precursors
male: spermatazoan
female: ???
Definition
ovum
Term
all non-germline cells
Definition
somatic cells
Term
a specialized structure within a cell that performs a specific function; analogous to an organ
Definition
organelle
Term
Functions of cell membranes

1. ???

2. defines the boundaries of the cell and its organelles

3. serves as a selective barrier allowing regulated transport in and out of the cell (or organelles)

4. allows the cell (or an organelle) to control its internal environment

5. contains enzymes and receptors (The membrane is ~50% protein with about 50 lipid molecules per protein.)
Definition
maintains the structural integrity of the cell
Term
Functions of cell membranes

1. maintains the structural integrity of the cell

2. ???

3. serves as a selective barrier allowing regulated transport in and out of the cell (or organelles)

4. allows the cell (or an organelle) to control its internal environment

5. contains enzymes and receptors (The membrane is ~50% protein with about 50 lipid molecules per protein.)
Definition
defines the boundary of the cell and its organelles
Term
Functions of cell membranes

1. maintains the structural integrity of the cell

2. defines the boundaries of the cell and its organelles

3. ???

4. allows the cell (or an organelle) to control its internal environment

5. contains enzymes and receptors (The membrane is ~50% protein with about 50 lipid molecules per protein.)
Definition
serves as a selective barrier allowing regulated transport in and out of the cell (or organelles)
Term
Functions of cell membranes

1. maintains the structural integrity of the cell

2. defines the boundaries of the cell and its organelles

3. serves as a selective barrier allowing regulated transport in and out of the cell (or organelles)

4. ???

5. contains enzymes and receptors (The membrane is ~50% protein with about 50 lipid molecules per protein.)
Definition
allows the cell (or an organelle) to control its internal environment
Term
Functions of cell membranes

1. maintains the structural integrity of the cell

2. defines the boundaries of the cell and its organelles

3. serves as a selective barrier allowing regulated transport in and out of the cell (or organelles)

4. allows the cell (or an organelle) to control its internal environment

5. ???
Definition
contains enzymes and receptors (the membrane is
~50% protein with about 50 lipid molecules per protein)
Term
the cell substance between the plasma membrane and the nucleus, containing the cytosol and organelles
Definition
cytoplasm
Term
the fluid component of the cytoplasm (also called the intracellular fluid or ICF)
Definition
cytosol
Term
??? = the cell’s membrane
Definition
plasma membrane
Term
The cytosol is very concentrated. It is actually more like a ??? than a fluid.
Definition
gel
Term
The nucleus stores the cell's hereditary material, or ???, and coordinates the cell's activities by regulating what proteins are made and how much of each protein is made and when.
Definition
DNA
Term
The nucleus stores the cell's hereditary material, or DNA, and coordinates the cell's activities by regulating what ??? are made and how much of each of these are made and when.
Definition
proteins
Term
??? divide the labor
of a cell. The nucleus directs overall cell activities.
Definition
Organelles
Term
the ??? contains most of the cell's DNA
Definition
nucleus
Term
Each ??? contains a small amount of mitochondrial DNA
Definition
mitochondrion
Term
The nucleus contains 1 or more ???, the site of ribosome assembly and RNA processing
Definition
nucleoli
Term
The nucleus contains 1 or more nucleoli, the site of ??? assembly and RNA processing
Definition
ribosome
Term
The nucleus contains 1 or more nucleoli, the site of ribosome assembly and ??? processing
Definition
RNA
Term
The strands of DNA in the nucleus are packaged with ???, forming a structure referred to as chromatin.
Definition
proteins
Term
The strands of DNA in the nucleus are packaged with proteins, forming a structure referred to as ???.
Definition
chromatin
Term
Organelles divide the labor
of a cell. The ??? directs overall cell activities.
Definition
nucleus
Term
??? serve as the basis for the storage and transfer of genetic information.

The two most important nucleic acids are DNA and RNA.

DNA is a double-stranded helix that stores encoded hereditary instructions for synthesizing proteins.

RNA functions in translating the genetic code during protein synthesis.
Definition
nucleic acids
Term
Nucleic acids serve as the basis for the ??? and transfer of genetic information.

The two most important nucleic acids are DNA and RNA.

DNA is a double-stranded helix that stores encoded hereditary instructions for synthesizing proteins.

RNA functions in translating the genetic code during protein synthesis.
Definition
storage
Term
Nucleic acids serve as the basis for the storage and ??? of genetic information.

The two most important nucleic acids are DNA and RNA.

DNA is a double-stranded helix that stores encoded hereditary instructions for synthesizing proteins.

RNA functions in translating the genetic code during protein synthesis.
Definition
transfer
Term
Nucleic acids serve as the basis for the storage and transfer of ???.

The two most important nucleic acids are DNA and RNA.

DNA is a double-stranded helix that stores encoded hereditary instructions for synthesizing proteins.

RNA functions in translating the genetic code during protein synthesis.
Definition
genetic information
Term
Nucleic acids serve as the basis for the storage and transfer of genetic information.

The two most important nucleic acids are DNA and ???.

DNA is a double-stranded helix that stores encoded hereditary instructions for synthesizing proteins.

RNA functions in translating the genetic code during protein synthesis.
Definition
RNA
Term
??? functions in translating the genetic code during protein synthesis.
Definition
RNA
Term
DNA contains instructions

then...

RNA is a copy of the instructions. Many copies can be made.

then...

??? are made from the instructions. Many copies of the protein can be made from each mRNA
Definition
proteins
Term
The genetic content of the nucleus (just over 3 billion DNA base pairs) is referred to as the ??? which contains about 25,000 genes.
Definition
human genome
Term
DNA to RNA to Protein 1. ??? 2. movement of mRNA into cytoplasm via nuclear pore 3. synthesis of protein
Definition
synthesis of mRNA in the nucleus

template is created
Term
DNA to RNA to Protein 1. synthesis of mRNA in the nucleus 2. ??? 3. synthesis of protein
Definition
movement of mRNA into cytoplasm via nuclear pore
Term
DNA to RNA to Protein 1. synthesis of mRNA in the nucleus 2. movement of mRNA into cytoplasm via nuclear pore 3. ???
Definition
synthesis of protein
Term
??? - a sequence of nucleotides within a segment of DNA that provides the coded instructions for synthesizing a specific protein.
We say that the this encodes for that protein.
We say that each protein is a specific product of this
Definition
gene
Term
??? - the process by which the genetic information encoded in a molecule of messenger RNA is translated to protein (an amino acid chain)
Definition
translation
Term
??? are the primary site of ATP production
Definition
mitchondria
Term
??? is produced primarily by the oxidation of pyruvate (from the catabolism of glucose) and fatty acids.
Definition
ATP
Term
ATP is produced primarily by the oxidation of ??? (from the catabolism of glucose) and fatty acids.
Definition
pyruvate
Term
ATP is produced primarily by the oxidation of pyruvate (from the catabolism of ???) and fatty acids.
Definition
glucose
Term
ATP is produced primarily by the oxidation of pyruvate (from the ??? of glucose) and fatty acids.
Definition
catabolism
Term
ATP is produced primarily by the oxidation of pyruvate (from the catabolism of glucose) and ???.
Definition
fatty acids
Term
an enclosed space or cavity
Definition
lumen
Term
The ??? is a three dimensional network of interconnected closed membrane saces (cisterns) and tubes
Definition
endoplasmic reticulum
Term
the endoplasmic reticulum is continuous with the ???
Definition
nuclear membrane
Term
The endoplasmic reticulum is tethered in place by the ???
Definition
cytoskeleton
Term
The rough ER is studded with ???
Definition
ribosomes
Term
The ??? is the site of protein synthesis for proteins destined for the ER, Golgi apparatus, lysosomes, peroxisomes, plasma membrane, or secretion from the cell
Definition
rough endoplasmic reticulum
Term
tubular shaped ER without associated ribosomes

site of lipid synthesis (including phospholipids, triglycerides, cholesterol and steroid hormones)

site of glycogen synthesis and catabolism in muscle and liver cells

site of intracellular Ca2+ storage

site of drug metabolism in hepatocytes
Definition
smooth endoplasmic reticulum
Term
site of lipid synthesis (including phospholipids, triglycerides, cholesterol and steroid hormones)
Definition
smooth endoplasmic reticulum
Term
site of glycogen synthesis and catabolism in muscle and liver cells
Definition
smooth endoplasmic reticulum
Term
site of intracellular Ca2+ storage
Definition
smooth endoplasmic reticulum
Term
site of drug metabolism in hepatocytes
Definition
smooth endoplasmic reticulum
Term
site for modification and packaging of proteins made in the RER
sorts and separates proteins according to their destinations
Proteins and glycolipids are glycosylated as they pass through this
Definition
golgi apparatus
Term
site for modification and packaging of proteins made in the RER
Definition
golgi apparatus
Term
sorts and separates proteins according to their destinations
Definition
golgi apparatus
Term
Proteins and glycolipids are glycosylated as they pass through this
Definition
golgi apparatus
Term
??? bud off the endoplasmic reticulum, carrying proteins and lipids to the cis face (forming face) of the Golgi apparatus. As proteins and lipids pass through successive layers of the Golgi apparatus, they are modified and sorted. Proteins and lipids leave the Golgi in vesicles that bud off the trans face (maturing face).
Definition
vesicles
Term
Vesicles bud off the ???, carrying proteins and lipids to the cis face (forming face) of the Golgi apparatus. As proteins and lipids pass through successive layers of the Golgi apparatus, they are modified and sorted. Proteins and lipids leave the Golgi in vesicles that bud off the trans face (maturing face).
Definition
endoplasmic reticulum
Term
Vesicles bud off the endoplasmic reticulum, carrying ??? and lipids to the cis face (forming face) of the Golgi apparatus. As proteins and lipids pass through successive layers of the Golgi apparatus, they are modified and sorted. Proteins and lipids leave the Golgi in vesicles that bud off the trans face (maturing face).
Definition
proteins
Term
Vesicles bud off the endoplasmic reticulum, carrying proteins and ??? to the cis face (forming face) of the Golgi apparatus. As proteins and lipids pass through successive layers of the Golgi apparatus, they are modified and sorted. Proteins and lipids leave the Golgi in vesicles that bud off the trans face (maturing face).
Definition
lipids
Term
Vesicles bud off the endoplasmic reticulum, carrying proteins and lipids to the cis face (forming face) of the ???. As proteins and lipids pass through successive layers of the Golgi apparatus, they are modified and sorted. Proteins and lipids leave the Golgi in vesicles that bud off the trans face (maturing face).
Definition
golgi apparatus
Term
Vesicles bud off the endoplasmic reticulum, carrying proteins and lipids to the ??? (forming face) of the Golgi apparatus. As proteins and lipids pass through successive layers of the Golgi apparatus, they are modified and sorted. Proteins and lipids leave the Golgi in vesicles that bud off the trans face (maturing face).
Definition
cis face
Term
Vesicles bud off the endoplasmic reticulum, carrying proteins and lipids to the cis face (forming face) of the Golgi apparatus. As proteins and lipids pass through successive layers of the Golgi apparatus, they are modified and sorted. Proteins and lipids leave the Golgi in vesicles that bud off the ??? (maturing face).
Definition
trans face
Term
3 types of vesicles bud off the trans face of the Golgi apparatus.

??? – carry molecules to be secreted from the cell

membrane renewal vesicles – fuse with the cell membrane to add lipids and proteins

primary lysosomes – vesicles that are filled with digestive enzymes and remain in the cytosol
Definition
secretory vesicles
Term
3 types of vesicles bud off the trans face of the Golgi apparatus.

secretory vesicles – carry molecules to be secreted from the cell

??? – fuse with the cell membrane to add lipids and proteins

primary lysosomes – vesicles that are filled with digestive enzymes and remain in the cytosol
Definition
membrane renewal vesicles
Term
3 types of vesicles bud off the trans face of the Golgi apparatus.

secretory vesicles – carry molecules to be secreted from the cell

membrane renewal vesicles – fuse with the cell membrane to add lipids and proteins

??? – vesicles that are filled with digestive enzymes and remain in the cytosol
Definition
primary lysosomes
Term
originate from Golgi apparatus

filled with digestive enzymes

these break down damaged organelles and material taken from outside the cell by endocytosis.

Useful nutrients are returned to the cytosol.

Any toxic compounds or compounds not useful to the cell are ejected from the cell by exocytosis.

after death, after cells have been deprived of oxygen for some time, the cytoplasm acidifies causing the membrane consisting of these to breakdown. The enzymes released from these digest the cell in a process called autolysis. Brain cells are the first to undergo this reaction, often destroying themselves within 4-5 minutes after breathing stops.
Definition
lysosomes
Term
??? originate from Golgi apparatus
and are filled with digestive enzymes
Definition
lysosomes
Term
??? break down damaged organelles and material taken from outside the cell by endocytosis.
Definition
lysosomes
Term
activation of ??? occurs when:

1. a primary lysosome fuses with the membrane of another organelle, such as a mitochondrion

2. a primary lysosome fuses with an endosome containing fluid or solid materials from outside the cell
Definition
lysosomes
Term
activation of lysosomes occurs when:

1. a primary lysosome fuses with the membrane of another ???, such as a mitochondrion

2. a primary lysosome fuses with an endosome containing fluid or solid materials from outside the cell
Definition
organelle
Term
activation of lysosomes occurs when:

1. a primary lysosome fuses with the membrane of another organelle, such as a mitochondrion

2. a primary lysosome fuses with an ??? containing fluid or solid materials from outside the cell
Definition
endosome
Term
these produce bile acids in hepatocytes

oxidize long chain fatty acids and certain amino acids, supplementing the energy produced by mitochondria

The oxidation of nutrients (both in the mitochondria and in peroxisomes) produces hydrogen peroxide, which is cytotoxic (toxic to cells).

these contain enzymes to neutralize the hydrogen peroxide.
Definition
peroxisomes
Term
??? produce bile acids in hepatocytes
Definition
peroxisomes
Term
??? oxidize long chain fatty acids and certain amino acids, supplementing the energy produced by mitochondria
Definition
peroxisomes
Term
??? contain enzymes to neutralize the hydrogen peroxide.
Definition
peroxisomes
Term
??? modified lipids and proteins; sorts and packages them in vesicles
Definition
golgi apparatus
Term
synthesizes lipids and performs other shit
Definition
smooth endoplasmic reticulum
Term
??? digests molecules or old cell parts
Definition
lysosomes
Term
supports and reinforces the plasma membrane

determines and maintains cell shape

gives cells mechanical strength

-resists deformation

-prevents excessive stretching by external forces

gives structure and organization to the cytoplasm

-tethers the nucleus, ER, Golgi apparatus, and mitochondria in place

mediates the internal movements that occur in the cytoplasm, such as the migration of organelles and mitotic movements of chromosomes.

-Motor proteins associated with components of this permit motion of one part of the cell relative to other parts (e.g. beating cilia, flagella, contraction of muscle cells) and the movement of organelles to specific locations within the cell
Definition
cytoskeleton
Term
supports and reinforces the plasma membrane

determines and maintains cell shape
Definition
cytoskeleton
Term
gives cells mechanical strength

-resists deformation

-prevents excessive stretching by external forces
Definition
cytoskeleton
Term
gives structure and organization to the cytoplasm

-tethers the nucleus, ER, Golgi apparatus, and mitochondria in place
Definition
cytoskeleton
Term
mediates the internal movements that occur in the cytoplasm, such as the migration of organelles and mitotic movements of chromosomes.

-Motor proteins associated with components of this permit motion of one part of the cell relative to other parts (e.g. beating cilia, flagella, contraction of muscle cells) and the movement of organelles to specific locations within the cell
Definition
cytoskeleton
Term
small fingerlike projections that increase the surface area of the cell membrane

found on the apical surface of epithelial cells in the small intestine and endothelial cells of nephron tubules in the kidneys

Increased surface area increases the rate of absorption of materials from the extracellular fluid.
Definition
microvilli
Term
minute hair-like organelles extending from the surface of a certain epithelial cells

beat in rhythmic waves, moving fluid in one direction across the cell surface

For instance, a female's oviducts are lined with these to assist in the movement of an egg (ovum) from the ovary to the uterus (womb).

The trachea and bronchi are lined with these to move mucous that is secreted by the cells lining the trachea up to the pharynx (throat) where the mucous is either coughed up or swallowed.
Definition
cilia
Term
minute hair-like organelles extending from the surface of a certain epithelial cells
Definition
cilia
Term
Each sperm has a single ??? which serves to propel the cell forward
Definition
flagellum
Term
large barrel-like protein complex

primary function is to degrade unneeded or damaged proteins by proteolysis (the hydrolysis of peptide bonds)

A human cell contains on average 30,000 these complexes.

it is shaped like a cylinder, with its active sites enclosed inside. The caps on the ends regulate entry into the chamber.
Definition
proteosome
Term
the primary function of these is to degrade unneeded or damaged proteins by proteolysis (the hydrolysis of peptide bonds)
Definition
proteosome
Term
the primary function of proteosomes is to degrade unneeded or damaged proteins by ??? (the hydrolysis of peptide bonds)
Definition
proteolysis
Term
the hydrolysis of peptide bonds
Definition
proteolysis
Term
Cells need to control the destruction of their own proteins, making sure they remove only those proteins that are damaged or no longer needed.

Unwanted (damaged, extra, or obsolete) proteins are marked for destruction by tagging with a chain of ??? proteins.

This targets the unwanted protein to proteosomes.

The ubiquinated protein chain is then pulled into the proteosome and hydrolyzed into small peptide fragments.
Definition
ubiquinated
Term
Cells need to control the destruction of their own proteins, making sure they remove only those proteins that are damaged or no longer needed.

Unwanted (damaged, extra, or obsolete) proteins are marked for destruction by tagging with a chain of ubiquitin proteins.

This targets the unwanted protein to ???.

The ubiquinated protein chain is then pulled into this and hydrolyzed into small peptide fragments.
Definition
protesomes
Term
Cells need to control the destruction of their own proteins, making sure they remove only those proteins that are damaged or no longer needed.

Unwanted (damaged, extra, or obsolete) proteins are marked for destruction by tagging with a chain of ubiquitin proteins.

This targets the unwanted protein to proteosomes.

The ubiquinated protein chain is then pulled into the proteosome and hydrolyzed into small ??? fragments.
Definition
peptide
Term
Cell division: mitosis followed by ???
Definition
cytokinesis
Term
Cell division: ??? followed by cytokinesis
Definition
mitosis
Term
??? is the division of the cell nucleus.
Definition
mitosis
Term
??? is the division of the cytoplasm into two daughter cells.
Definition
cytokinesis
Term
The genetic information encoded in DNA is organized into ???. During mitosis, these are replicated and one copy of each is transmitted to the daughter cells.
Definition
chromosomes
Term
The genetic information encoded in DNA is organized into chromosomes. During ???, the chromosomes are replicated and one copy of each is transmitted to the daughter cells.
Definition
mitosis
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