Term
What is the role of ATP in metabolic reactions? |
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Definition
Transfer energy released from catabolic reaction to anabolic reaction that requires energy |
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Term
How efficient are metabolic reactions? |
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Definition
ATP traps only about 40% of energy, 60% is lost as heat |
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Term
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Definition
Chemicals that cells need for growth |
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Term
What are the different classes of nutrients? |
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Definition
Carbohydrates: absorbed as monosaccharides, energy production
Lipids: absorbed as fatty acids/glycerol/monoglycerides, energy storage, hormones
Proteins: absorbed as amino acids, structural, hormones, enzymes
Minerals: inorganic coenzymes
Vitamins: organic coenzymes
Water: solvent, hydrolysis reactions, lubricant |
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Term
What are the digestion products of carbs? |
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Definition
Monosaccharides, goes through different processes such as ATP production/amino acid synthesis/glycogenesis/lipogenesis/excretion in urine |
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Term
How do carbs enter/exit the cell? |
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Definition
Active transport to get in and facilitated diffusion to get out |
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Term
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Definition
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Term
What are the 4 steps of cellular respiration? |
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Definition
1. Glycolysis
2. Pyruvate forms acetyl CoA
3. Krebs cycle
4. Electron transport chain |
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Term
How does cellular respiration store potential energy? |
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Definition
Pumps H+ ions into inner mitochondrial space creating concentration and electrical gradients |
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Term
What are the channels attached to that H+ flows through? |
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Definition
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Term
What is the final electron acceptor in cellular respiration? |
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Definition
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Term
What are the 4 major outcomes of the 4 major steps of cellular respiration? |
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Definition
1. 2-4 ATP generated through glycolysis
2. Acetyl CoA is formed
3. 2 ATP generated through Krebs cycle
4. Cytochrome proteins embed into inner mitochondrial membrane generating 32 ATP through electron transport chain |
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Term
What is the process of glucose storage and how does it work? |
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Definition
Glycogenesis, whenever glucose is not need for ATP production it is stored as glycogen, this is stimulated by insulin |
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Term
What is the process of glucose release called and how does it work? |
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Definition
Glycogenolysis, stimulated by epinephrine and glucagon, stored glycogen is converted to glucose and released |
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Term
What is the process of forming glucose from fats/proteins and how does it work? |
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Definition
Gluconeogenesis, new glucose is formed from lactic acid/amino acids/fats, occurs on large scale when starving/fasting/eating low carb diet |
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Term
What do lipids combine with in order to be transported? |
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Definition
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Term
What are the digestion products of lipid metabolism? |
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Definition
Glycerol, fatty acids, monoglycerides, used for energy storage/energy reserves/steroid hormones/eicosanoids/cell membranes/modify proteins |
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Term
How do lipids enter the cell? |
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Definition
Small fatty acids by diffusion, larger ones and monoglycerides as micelles/chylomicrons |
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Term
What is lipid metabolism called and how does it work? |
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Definition
Lipolysis, catabolic oxidation of lipids to yield glucose, stimulated by epinephrine/norepinephrine/cortisol, beta oxidation involved |
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Term
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Definition
Convert excess dietary intake of carbs/proteins/fats into triglycerides |
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Term
What are the digestion products of protein metabolism? |
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Definition
Amino acids, used as enzymes/transport molecules/antibodies/contractile elements/structure/hormones |
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Term
How do proteins enter the cell? |
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Definition
Active transport, stimulated by insulin/HGH |
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Term
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Definition
Transfer of amino group from amino acid to pyruvic acid to form nonessential amino acid |
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Term
What the 3 key molecules in metabolism of nutrients? |
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Definition
Acetyl-CoA, glucose-6-phosphate, pyruvic acid |
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Term
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Definition
Inborn metabolic error, missin phenylalanine hydroxylase, cannot convert phenylalanine to tyrosine, phenylalanine accumulates in blood, mental retardation, diagnosed at birth |
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Term
What is the absorptive state of metabolism? |
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Definition
Ingested nutrients enter bloodstream and glucose readily available, right after meal, regulated by insuling/HGH/TH, ATP manufactured from glucose |
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Term
What is the postabsorptive state of nutrient metabolism? |
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Definition
During fasting, after ingested meal has been absorbed, regulated by glucagon/epinephrine/norepinephrine/cortisol/TH, maintain normal blood glucose levels, gluconeogenesis |
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Term
What is basal metabolic rate? |
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Definition
Energy needs of body at rest, measured after 12 hour fast, measured by O2 consumption and heat generation |
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Term
What are the mechanisms of body temperature homeostasis? |
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Definition
Hypothalamic thermostat located in the preoptic area, heat is produced when sympathetic NS increases cellular metabolic rates, exercise, shivering, heat is converted through peripheral vasoconstriction, heat is lost through radiation/conduction/convection/evaporation |
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Term
How is a fever caused and what are the responses? |
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Definition
Caused by infection/tumor/MI/surgery, responses are chills/crisis |
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Term
How is hypothermia caused and what are the responses? |
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Definition
Caused by exposure/injuries/illnesses, responses are temperature drop/cardiac arrest |
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Term
How does the hypothalamic feeding center regulate food intake? |
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Definition
Always on, stimulated by cold temperatures, stimulated by HGH/androgens/progesterone, inhibited by gastric distension and CCK |
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Term
What is the hypothalamic satiety center? |
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Definition
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Term
What is considered brain food? |
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Definition
Multivitamins, antioxidant supplements, foods rich in antioxidants, fish oil daily is best |
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Term
How are minerals important to the body/how are they ingested? |
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Definition
Ingested as food/pills, make up 4% of body's mass, required as catalysts/coenzymes |
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Term
What are common minerals? |
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Definition
Calcium: bone/teeth/coenzyme/endocrine/NS
Phosphorous: bone/teeth/buffer systems/endocrine/DNA and RNA
Iron: coenzyme/transport
Iodine: endocrine
Sodium: buffer systems/fluid balance/NS
Potassium: NS |
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Term
What are the fat-soluble vitamins? |
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Definition
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Term
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Definition
Body weight is 20% above desired standard, excessive adipose tissue, increased risk of disease, affects 1/3 of US adults |
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Term
What are the 3 types of obesity? |
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Definition
Hypertrophic: adult onset, number of fat cells constant but content of cells increases
Hyperplastic: child onset, number of fat cells increases and content of cells increases
Morbid: weight is 2X the ideal weight, life threatening |
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Term
What are causes and treatments of obesity? |
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Definition
Caused by hypothalamic/thyroid disorders, early eating habits, cultural values, emotional disorders
Treated by reduced caloric intake, exercise, medically supervised fast |
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Term
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Definition
Loss of water and NaCl in sweat, muscle cramps after activity |
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Term
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Definition
Excessive fluid loss, increasing fatigue, weakness, anxiety, drenching sweats, circulatory collapse |
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Term
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Definition
The body cannot eliminate excess heat when high humidity, brain damage, cardiac arrest, decreased sweating, sking is hot/flushed/dry, rapid pulse |
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Term
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Definition
State of poor nutrition, caused by inadequate food intake/nutrient imbalance/malabsorption |
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Term
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Definition
Low calories, low protein, retarded growth, emaciation |
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Term
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Definition
Normal calorie intake, incomplete proteins, abdominal edema, enlarged liver |
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Term
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Definition
Loss of energy stores, 1st stage carbs/lipids/nonessential fats are used, 2nd stage uses all stored fat, 3rd stage uses essential proteins causing death |
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