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Ch. 1
The Study of Body Function
21
Physiology
Undergraduate 1
01/22/2009

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Term
Describe the topics covered in human physiology:
Definition
It is the study of biological function-from cell to tissue, tissue to organ, organ to system and how the organism as a whole accomplishes tasks essential for life.
Term
What sequences are emphasized in the study of physiology?
Definition
Cause and effect
Term
How is knowledge of physiological mechanisms obtained?
Definition
From data observed experimentally.
Term
What other sciences do physiology overlap?
Definition
Chemistry, physics, pathophysiology (function of diseased or injured body systems) and comparative physiology (physiology of animals)
Term
Describe the 3 characteristics of the scientific method:
Definition

1- assumption that the subject under study can be explained in terms we can understand

2- descriptions and explanations are honestly based on observations of the natural world, and can be changed by new observations

3- Humility. The scientist must be willing to change theories based on the weight of the evidence.

Term
Define homeostasis:
Definition
The state of "dynamic constancy" of the internal environment depite changing conditions of the external environment.  Maintained by negative feedback loops.
Term
Identify the components of negative feedback loops:
Definition

1) A sensor-detecting change in the internal environment

2) Integrating center-determines response

3) An effector- that can be activated by the sensor

Term
What is negative feedback?
Definition
When the body's sensor detects a deviation from the set point and stimulates an effector to bring the deviation back to the set point.  Since it is always in a negative or reverse direction back to the set point it is called "negative" feedback.
Term
Explain the role of antagonistic effectors in maintaining homeostasis:
Definition
The increasing activity of one effector is accompanied by the decreasing activity of an antagonistic effector, and vice versa.  This allows for a finer degree of control than if an effector was just shut on and off (tonic control). ex. sweating and shivering bring temperature back to set point
Term
Describe the nature of positive feedback loops:
Definition
Instead of antagonistic control, the action of effectors amplifies the changes that stimulated the effectors. ex. a thermostat that increases heat production in response to a rise in temperature; uterine contractions during childbirth: fetus feels stress and releases oxytocin which stimulates uterine contraction, which creates more stress ect.
Term
Give an example of how negative feedback loops involving the endocrine system helps to maintain homeostasis after eating:
Definition

Eating->raises blood glucose->pancreatic islets (of Langerhans) act as sensor, integrating center and effector; detect increased blood glucose

->stimulation of pancreatic islets increase insulin

->increased cellular uptake of glucose->decreased blood glucose

Term
Give an example of how a negative feedback loop involving the endocrine system can help to maintain homeostasis after fasting:
Definition

Fasting->lowers blood glucose->pancreatic islets(of Langerhans) act as sensor, integrating center and effector; detect decreased blood glucose-> stimulation of pancreatic islets decrease insulin-> triggers glucagon production->decreased cellular uptake of glucose->liver secretes glucose

->increased blood glucose

Term

Give an example of how negative feedback loops involving the nervous system help to maintain homeostasis:

Definition
Lying down to standing up position->blood pressure falls=stimulus->baroreceptors (blood pressure receptors)stimulated=sensor->stimulates sensory nerve fibers->medulla oblongata=integrating center->motor nerve fibers->heart=effector->heart rate increases->blood pressure rises=response
Term
A resonse loop always begins with a ___ and always ends with a ____:
Definition
Stimulus; response
Term
What is the purpose of the scientific method?
Definition
To give us reliable, dependable information.
Term
What is a response loop composed of?
Definition

1)stimulus

2)sensor/receptor

3)afferent pathway

4)integrating center w/ set point

5)efferent pathway

6)effector

7)response

Term
What is intrinsic control?
Definition
Control is built into organ being regulated
Term
What is extrinsic control?
Definition
Control comes from outside of organ being regulated
Term

What is local control?

Definition
When some metabolism of a cell only affects a small number of surrounding cells.
Term
Which effectors of the baroreceptor reflex are under antagonistic control?
Definition
SA node
Term
Which effectors of the baroreceptor reflex are under tonic control?
Definition
Arterial smooth muscle and ventricular myocardium
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