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ch13 Microbe-human interaction
terms
27
Microbiology
Undergraduate 1
03/28/2012

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Term
Virulence
Definition
degree of pathogenicity. intracellular are more virulent
Term
Virulence factors
Definition
properties that enable a MO to establish itself on or within a host of a particular species and enhance its potential to cause disease; e.g. mechanisms of adhesion (such as fimbria, capsules, flagella), exotoxins, endotoxins, and exoenzymes.
Term
Pathogenicity
Definition
ability of MO to cause pathogenic changes
Term
True pathogen
Definition
cause harm/disease in healthy persons with normal immune defenses.
Ex: Salmonella typhi/Typhoid fever, HIV, tuberculosis/Mycobacterium tuberculosis; Shigellosis
Term
Opportunistic pathogen
Definition
potential to cause disease when the host's immunity defenses are compromised. Not designed to be pathogens. (normal flora gone wrong)
Term
Infection
Definition
condition when contaminating MOs overcome host defenses, multiply & cause disease
Term
Cutaneous populations of microbes
Definition
*Transient -cling to but dont grow on superficial layers of skin
*Permanent residents -reside in the deeper layers of epidermis/glands
Term
Subclinical/asymptomatic infection
Definition
Infection with no noticeable symptoms even tho microbe is active in host
Term
Period of incubation
Definition
Time of initial contact with infection (port of entry) to the appearance of the first symptoms
Term
Epidemic
Definition
Disease is increasing beyond what is expected
Term
Parasitism
Definition
Host provides parasitic microbe with nutrients and habitat/parasite dependent on host
Term
Prodromium
Definition
Earliest notable symptoms of infection (1-2 days)
Term
Herd immunity
Definition
Mass immunization to limit spread of disease
Term
Microbotia
Definition
Microscopic living organisms of a region (e.g. GI tract). Normal flora.
Term
Nosocomial infection
Definition
infectious diseases acquired in hospital
Term
Chronic disease
Definition
disease that persists over long period of time, slow progression
Term
Emerging infectious disease
Definition
infectious disease occurence that has potential to increase in near future
Term
Non-communicable disease
Definition
do not spread from host to host
Term
Endemic disease
Definition
concentrated in one (geographic) area at a relatively stable rate
Term
Acute disease
Definition
comes on rapidly, severe, short-lived
Term
Epidemiology
Definition
study of frequency & distribution of disease and other health-related factors in human population
Term
Adhesion
Definition
process in which microbes gain more stable footing at the portal of entry
Term
Infectious dose
Definition
the minimum number of microbial cells required to initiate infection in the host
Term
Portal of exit
Definition
pathogens are released thru specific means; cough, sneeze, etc
Term
Dysentry
Definition
GI disorders
-Intestinal inflammation, especially the colon
Term
cilia elevator
Definition
upper respiratory tract - works with mucus to expel
Term
Parenteral route
Definition
(portal of entry)
*skin, abrasions, insect bites, hypodermic needle injection sites, etc
*invasion of microbes thru the skin
**Invasion of skin by sharp object for example will deposit contaminating microbes right into the blood system and that is called the "parenteral route of infection."** (board)
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