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Ch. 10
Molecular Biology of Inheritance
14
Biology
Undergraduate 4
02/14/2012

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Term
DNA
Definition
Nucleic acid polymer produced from covalent bonding of nucleotide monomers that contain the sugar deoxyribose; the genetic material of nearly all organisms
Term
Hershey and Chase
Definition
Experiment that relied on a chemical difference between DNA and protein. In DNA, phosphorus is present but sulfur is not, and in protein, sulfur is present but phosphorus is not.
Term
Adenine
Definition
one of the four bases in the structure of nucleotides in DNA.
Term
guanine
Definition
one of the four bases in the structure of nucleotides in DNA. pairs with cytosine.
Term
cytosine
Definition
one of the four bases in the structure of nucleotides in DNA. pairs with guanine
Term
thymine
Definition
one of the four bases in the structure of nucleotides in DNA. pairs with adenine
Term
complementary base pairs
Definition
hydrogen bonding between particular bases. In DNA, thymine pairs with adenine, and guanine pairs with cytosine. In RNA uracil pairs with adenine and guanine pairs with cytosine
Term
Double Helix
Definition
Double spiral; describes the 3-D shape of DNA
Term
Rosland Franklin
Definition
• Was an expert in x-ray crystallography
• Used this technique to examine DNA
• Concluded that DNA was some sort of helix
• Phosphate bonds were on the outside of the molecule
Term
Watson and Crick
Definition
• DNA consists of two nucleotide strands – Molecule is a double helix
• Strands run in opposite directions – antiparallel
• Strands are held together by hydrogen bonds between bases
Term
antiparallel
Definition
DNA strands run in opposite directions
Term
semiconservative replication
Definition
duplication of DNA resulting in two double helix molecules, each having one parental and one new strand.
Term
DNA replication
Definition
• Each parent strand remains intact
• Every DNA molecule is half “old” and half “new”
Term
3' and 5'
Definition
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