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Ch1-5,7-9
Microbiology Author:Talaro
43
Microbiology
Undergraduate 2
09/18/2011

Additional Microbiology Flashcards

 


 

Cards

Term
Genetics
Definition
The study of heredity
Term
Genome
Definition
total of genetic material of an organism
Term
Genome of Cell is ___
Definition
DNA
Term
Genome of virus
Definition
DNA or RNA
Term
What shape are bacterial chromosome?
Definition
Single circular loop
Term
What is the shape of eukaryotic chromosomes?
Definition
Multiple and linear
Term
Chromosomes are subdivided into
Definition
GENES
Term
Fundamental unit of heredity resonsible for a given trait
Definition
GENES
Term
3 basic categories of genes
Definition

Structural Genes (proteins)

Code for RNA

Regulatory genes (gene expression)

 

Term
All types of genes that constitute the genetic makeup is called
Definition
genotype
Term
The expression of the genotype creates observable traits called
Definition
phenotype
Term
Basic unit of DNA stucture
Definition
Nucleotide
Term
3 parts of a nucleotide
Definition

deoxyribose (sugar)

Phosphate group

Nitrogenous base : ATCG

Term
The backbone of nucleotide
Definition
Sugar-phosphate linkage
Term

# of bonds between A & T in DNA

 

Definition
2 bonds
Term
# of bonds between C & G in DNA
Definition
3 bonds
Term
_____ unwinds and unzips the DNA double helix
Definition
Helicase
Term

______ adds nucleotides during DNA Replication.

2 types:

Definition

DNA polymerase III

- leading strand

- lagging strand

Term
______ links DNA fragments during DNA replication
Definition
Ligases
Term
Semi-conservative
Definition
Term used to describe DNA replication b/c each chromosome ends up with a new and old DNA
Term
Transcription
Definition
Info transfer from DNA to RNA molecules
Term
Translation
Definition
Info contained in RNA used to produce protein
Term
1 amino acid = ____ nucleotides on RNA
Definition
3
Term
A protein's structure determines...
Definition
it's shape and function
Term
3 steps of translation
Definition
initiation, elongation, termination
Term
Describe translation
Definition
Start codon (AUG); tRNA molecules matches it's anticodon to codon of mRNA
Term
Introns
Definition
intervening non-coding DNA segments in mRNA transcription segments
Term
Operons
Definition
A set of genes that regulate when genes need to be activated
Term
2 types of operons:
Definition
Inducible operons & repressible operons
Term
Inducible operons
Definition
Operon turned ON by substrate
Term
repressible operon
Definition
operons that are turned OFF by substrates; generally ON but turned off when there's enough
Term
Mutation
Definition
change in phenotype due to change in genotype
Term
Wild type mutation
Definition
natural, nonmutated characteristic
Term
Cause of mutations (2 types)
Definition
Spontaneous mutations & Induced mutations
Term
Spontaneous Mutations
Definition
random change in DNA due to error in replication
Term
Induced Mutations
Definition
result from exposure to known Mutagens
Term
Mutagens
Definition
causes "induced mutation" thru physical or chemical agents
Term
Categories of Mutations: Large mutations?
Definition
whole DNA segments are gained / lost
Term
Categories of Mutations: Point Mutations?
Definition
addition, deletion, substitution of few bases
Term
Categories of Mutations: Missense mutation?
Definition
change in single amino acid
Term
Categories of Mutations: nonsense mutation?
Definition
change normal codon to stop codon
Term
Categories of Mutations: Silent Mutation?
Definition
alters a base but doesn't change amino acid
Term
Categories of Mutations: Back-mutation?
Definition
mutated gene reverses to its original base composition
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