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CH. 06 Energy, Enzymes & Metabolism - (Biology 1A)
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14
Biology
Undergraduate 1
04/29/2012

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Term
Catabolic pathway
Definition
Result in the breakdown of molecules into smaller components. (exergonic)
Term
Anabolic pathway
Definition
Involves the synthesis of larger molecules from small. (endergonic)
Term
Exergonic reaction
Definition
Chemical reactions that release free energy and occur spontaneously.
Term
Endergonic reaction
Definition
Chemical reactions that require an addition of free anergy and do not proceed spontaneously.
(ADP+P -> ATP)
Term
ATP hydrolysis in driving other reactions
Definition
Coupling ATP hydrolysis with other reactions can change a reaction that would have been endergonic to one that is exergonic.
Term
Enzymes as catalysts
Definition
Enzymes lower the activation energy needed for the substrates to reach a transition state.
(APT + glucose -> Glucose-phosphate + ADP)
Term
Enzyme shape changes in enzyme-catalyzed reactions
Definition
Enzymes may donate amino acids to catalyze reactions, but the amino acids are returned to the enzyme after the reaction is complete.
Term
Cause of substrate specificity in enzymes
Definition
Conformational changes in the enzyme-substrate complex cause the substrate to bind tightly with the enzyme called an induced fit. Only after this can the reaction take place.
Term
Affects on enzymes - temperature
Definition
High temperatures may inhibit an enzyme's ability to function properly. Very high temperatures my cause it to become denatured and not at all functional.
Term
Affects on enzymes - pH
Definition
Enzymes may not functional as well if the pH is altered from that which they normally function in.
Term
Affects on enzymes - inhibitors (competitive)
Definition
Molecules that bind to the active site on an enzyme and inhibit the ability of the substrate to bind.
Term
Affects on enzymes - inhibitors (noncompetitive)
Definition
Binds to noncovelently an enzyme at a location outside the active site (allosteric site) and inhibits the enzyme's function.
Term
NAD+
Definition
Can be used to make NAHD which can be used to produce ATP
Term
End of chapter 6
Definition
Beginning of chapter 7
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