Term
| Electric current reulsts from_____ |
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Definition
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Term
| Antibacterial and Antiprotozoals are more active as____whereas anesthetics are more active when_____ |
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Definition
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Term
| What is the van't Hoff equation for electrolytes? |
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Definition
∏V= inRT
i= number of ions |
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Term
What are buffers?
T/F
High buffers are always good |
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Definition
Solutions that resist pH changes
FALSE |
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Term
| Why is buffering important? |
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Definition
Minimizes irritation
Enhances stability
Improves solubility
Enhances drug bioavilability |
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Term
What is the normal pH of lacrimal fluid?
Most opth. drugs are weakly____and have___buffering capacity. |
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Definition
pH=7.4
weakly acidic and low buffering capacity |
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Term
| What are the components of a buffer? |
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Definition
weak acid and its conjugate base
weak base and its conjugate acid |
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Term
| What is the buffer equation for acids? |
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Definition
pH= pKa + log(salt/acid)
p means -log[x]
pKw= pH+pOH |
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Term
| What is the buffer equation for bases? |
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Definition
| pH= pKw-pKb+log (base/salt) |
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Term
What molar ratio of sodium acetate and acetic acid should we suse to prepare an acetate buffer of pH 5.0?
pKa of acetic acid =4.76 |
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Definition
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Term
What is the pH of a solution containing 0.1 mole of ephedrine and 0.01 mole of ephedrine HCl per liter of solution?
pKb of ephedrine= 4.64, T= 25 C |
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Definition
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