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Cerebellum
Test IV Material
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Graduate
04/10/2011

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Term
Are the following specific or general terms to describe the cerebellum?
Asynergia, Dysmetria, Dysdiadochokinesia, Intention Tremor, Ataxia, Truncal Ataxia, Titubation.
Definition
Specific
Term
Are the following specific or general terms to describe the cerebellum?
Uncoordination, Hypotonia, Dysarthria, Nystagmus, Nausea/Vomiting, Pendular.
Definition
General
Term
As a task or movement gets more complex what gets more involved?
Definition
The cerebellum
Term
Functions mainly to regulate or control movemens, particularly skilled movements that are initiated by the cerebral cortex.
Definition
Cerebellum
Term
Has the ability to compare actual ad intended movement and make adjustments in that movement via connections with other motor system structures.
Definition
Cerebellum
Term
Functions to maintain or regulate postue, muscle tone, and equilibrium.
Definition
Cerebellum
Term
Receives a continuous stream of inputs from receptors in muscles, tendons, and joints and skin and from vestibular, visual, and auditory centers.
Definition
Cerebellum
Term
Is the cerebellum involved in conscious perception?
Definition
No
Term
Receives input from cortical association and motor areas
Definition
Cerebellum
Term
Cerebellar ___ reach the brain stem, the spinal cord, and the cortex via the VL and VA nuclei of the thalamus which also receie basal ganglia efferents
Definition
Efferents
Term
Pathologies involving this structure include disturbances of voluntary movement, gait, muscle tone and equilibrium
Definition
Cerebellum
Term
The inability to adjust to the impulses innervating various muscles participating in a movement so that the range, direction, and force of movements is altered
Definition
Asynergia
Term
Name the 3 things that the cerebellum structurally consists of
Definition
Cerebellar Cortex
Medullary Substance
Deep Cerebellar Nuclei
Term
Superficial mantle of gray matter, composed of numerous transverse oriented folia that serve to increase surface area.
Definition
Cerebellar Cortex
Term
Internal white matter
Definition
Medullary substance
Term
How many pairs of deep cerebellar nuclei are there?
Definition
4
Term
Name the 4 pairs of deep cerebellar nuclei in order from lateral to medial.
Definition
Dentate
Globose
Emboliform
Fastigial
Term
What are the globose and emboliform nuclei referred to together?
Definition
Interposed Nuclei
Term
Embedded in the white matter
Definition
Deep Cerebellar Nuclei
Term
Name the 3 lobes of the cerebellum
Definition
Anterior
Posterior
Flocculonodular
Term
What is the largest lobe of the cerebellum?
Definition
Posterior
Term
The part of the cerebellum that lies rostral to the primary fissure.
Definition
Anterior Lobe
Term
Divides the anterior and posterior lobes of the cerebellum
Definition
Primary Fissure
Term
The largest and phylogenetically newest part of the cerebellum
Definition
Posterior Lobe
Term
Phylogenetically the oldest part of the cerebellum and most closely related to the vestibular system
Definition
Flocculonodular Lobe
Term
A highly infolded structure with a large surface area but idential morphology throughout
Definition
Cerebellar cortex
Term
Name the 3 layers of the cerebellar cortex
Definition
Molecular Layer
Purkinje Cell Layer
Granular Layer
Term
The molecular layer of the cerebellar cortex contains 2 types of neurons.
Definition
Basket Cells
Stellate Cells
Term
Which layer of the cerebellar cortex contains processes of other neurons, particularly dendrites of the Purkinje cells?
Definition
Molecular Layer
Term
Other than the cerebellum, where else can you find Purkinje Cells?
Definition
Nowhere
Term
Contains great numbers of large, flask-shaped neurons whose extensive dendrites reach cloe to the surface of the molecular layer.
Definition
Purkinje Cell Layer
Term
Regularly arranged with elaborate dendritic trees spread out on a plane at right angles to the longitudinal axis of the folia, enabling purkinje cells to receive input from connection with climbing fibers and granule cells
Definition
Purkinje cell bodies
Term
Where do purkinje cells receive input from?
Definition
Connection with climbing fibers and granule cells
Term
The output cell of the cerebellar cortex
Definition
Purkinje cells
Term
Most axons of purkinje cells penetrate what layer?
Definition
Granular Layer
Term
Most axons of purkinje cell penetrate the granular layer and extend into the white matter to terminate where?
Definition
The deep cerebellar nuclei
Term
Some pukinje cell axons bypass the deep cerebellar nuclei to terminate where?
Definition
Vestibular nuclei
Term
Inhibitory to their target nuclei
Definition
Purkinje cells
Term
The granular layer of the cerebellar cortex contains 2 types of neurons.
Definition
Granule cells
Golgi cells
Term
Main cell type in the granular layer that is densely packed
Definition
Granule cells
Term
The axons of granule cells extend into the molecular layer and split into a t-shape to form what?
Definition
Parallel fibers
Term
The parallel fibers runa long the longitudinal axis of the folia, making synapses with what?
Definition
Purkinje dendrites
Term
Afferents to the cerebellum convey impulses primarily to where?
Definition
Cerebellar cortex
Term
Inputs to the cerebellum arrive primarily via what?
Definition
1. Inferior cerebellar peduncle (dorsal spinocerebellar, vestibulocerebellar, reticulocerebellar, olivocerebellar, and cuneocerebellar fibers)
2. Middle Cerebellar Peduncle (corticopontine/pontocerebellar fibers)
3. Superior Cerebellar Peduncle (ventral spinocerebellar fibers)
Term
Cerebellar afferent fibers include __ fibers which are thin fibers originating in the inferior olivary nuclei
Definition
Climbing fibers
Term
Cerebellar afferent fibers include climbing fibers which wind along purkinje dendrites, and thick __ fibers which end in the granular layer where the synapse with what?
Definition
Mossy
Granule Cell Dendrites
Term
Cerebellar efferent fibers arise from all of the deep cerebellar nuclei and from specific regions of the cerebellar cortex and take one of the following 3 routes.
Definition
1. Cortex to vestibular nuclei
2. Efferentsin Superior Cerebellar Peduncle
3.Efferents in the infeior cerebellar peduncle
Term
Direct projections arising from the cortex of the vermis and from the flocculonodular lobe pass to the ipsilateral vestibular nuclear complex
Definition
Cortex to vestibular nuclei
Term
These fibers arise in the deep cerebellar nuclei (dentate, emboliform, and globose)
Definition
Efferents in te superior cerebellar peduncle
Term
Can either:
1. ascend through the contralateral red nucleus of the thalamus (VL) and ultimately to the primary motor corte (area 4) (dentatorubrothalamic tract, interpositorubral tract)
2. Descend to areas in the brain stem such as the contralateral inferior olive (via red nucleus) in the central tegmental tract.
Definition
Efferents in the superior cerebellar peduncle
Term
These fibers originate in the fastigial nucleus and descend (crossed and uncrossed) primarily to vestibular and reticular nuclei in the brain stem
Definition
Efferents in the inferior cerebellar peduncle
Term
ALL impulses arriving (afferents) in the cerebellum are ___ on purkinje cells, granule cells, o on deep cerebellar nucli
Definition
Excitatory
Term
ALL impulses leaving (efferents) te cerebellar cortex (purkinje axons) are ___ on deep cerebellar an vestibular nuclei.
Definition
Inhibitory
Term
Axons of deep cerebellar nuclei are __
Definition
Excitatory
Term
There exists a ___ organization within the cerebellum such that certain areas of the cerebellar cortex send projections to certain nuclei
Definition
Somatotopic
Term
The cerebellar cortex has been divided functionally into 3 regions.
Definition
Vestibulocerebellum
Spinocerebellum
Cerebrocerebellum
Term
Function term for flocculonodular lobe
Definition
Vestibulocerebellum
Term
Has reciprocal connections with the vestibular nuclei
Definition
Vestibulocerebellum
Term
Concerned with influencing eye movement and controlling posture and equilibrium via efferent connections with the vestibular system.
Definition
Vestibulocerebellum
Term
Consists of vermal and paravermal areas of the cerebellar cortex which send projections primarily to the fastigal (vermis) and interposted nuclei
Definition
Spinocerebellum
Term
This regions receives extensive input from the spinal cord an is concerned with control of proximal limb movements via descending spinal pathways (vestibulospinal, reticulospinal, rubrospinal, and medial corticospinal)
Definition
Spinocerebellum
Term
Also exerts control over muscles involved in speech production
Definition
Vermal area
Term
Consists of lateral cerebellar hemispheres which send projections primarily to the dentate nuclei
Definition
Cerebrocerebellum
Term
This system has the most extensive thalamocortical projections and is concerned with the coordination of distal limb movements via connections with corticospinal and rubrospinal tracts
Definition
Cerebrocerebellum
Term
The most common type of cerebellar lesion seen in humans
Definition
Lateral Cerebellar Hemispheres OR Dentate Nucleus
Term
Affects primarily skilled voluntary movements
Definition
Lesion to lateral cerebllar hemispheres or dentate nucleus
Term
Lesion to the lateral cerebellar hemisphere or dentate nucleus, are the symptoms ipsi or contra?
Definition
Ipsi
Term
Name 6 symptoms of a lesion to the lateral cerebellar hemispheres or dentate nucleus
Definition
1. Hypotonia
2. Asynergia
3. Dysmetria
4. Dysdiadochokinesia
5. Decomposition of movement
6. Intention Tremor
Term
Decreased muscle tone. Deet tendon reflexes are decreased and possess a pendular quality.
Definition
Hypotonia
Term
When you kick out and it kicks back, like a swinging motion
Definition
Pendular
Term
Range, direction, and force of muscle contractions are inappropriate.
Definition
Asynergia
Term
Name 3 symptoms of asynergia
Definition
Dysmetria
Dysdiadochokinesia
Decomposition of movement
Term
Inability to gauge distances (over/undershoot)
Definition
Dysmetria
Term
Inability to perform rapidly alternating movements of the extremities
Definition
Dysdiadochokinesia
Term
Inability to perform compound movements
Definition
Decomposition of movement
Term
Tremeor with movement; not present at rest
Definition
Intension tremor
Term
This type of pathology is generally seen secondary to chronic alcohol abuse which, for unknown reasons, causes effects primarily in the anterior lobe of the cerebellum.
Definition
Anterior lobe of cerebellum lesion
Term
Symptoms for this pathology are typical of spinocerebellar damage
Definition
Anterior lobe of cerebellum
Term
If you have a lesion to the anterior lobe of the cerebellum name 2 common symptoms.
Definition
Ataxia
Dysarthria
Term
Irregular muscle contractions involving the axial and proximal extremity muscles; evident during stance and gait
Definition
Ataxia
Term
Controls proximal limb movement and speech
Definition
Spinocerebellar
Term
Cannot maintain balance on a narrow surface
Definition
Ataxia
Term
Incorrdination of speech
Definition
Dysarthria
Term
Most commonly due to tumors of young children known as medulloblastomas
Definition
Lesion to flocculonodular lobe
Term
Such tumors arise in the roof of the 4th ventricle
Definition
Medulloblastomas
Term
Name 4 symptoms of a lesion t the flocculonodular lobe
Definition
1. Nystagmus at rest
2. Truncal ataxia
3. Titubation
4. Nausea/Vomiting
Term
Seen primarily during upright activities; disappears when lying down
Definition
Truncal ataxia
Term
Head oscillations, cannot be still, contant movement
Definition
Titubation
Term
Are cerebellar issues seen contralaterally or ipsilaterally?
Definition
Ipsilaterally
Term
Ventral spinocerebellar information goes through what?
Definition
Superior cerebellar peduncle
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