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Central Nervous System
Brain and Spinal Cord
141
Anatomy
Undergraduate 3
01/21/2014

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Term
What are the two components of the CNS?
Definition
1. Brain
2. Spinal cord
Term
What are the 3 main parts of the brain?
Definition
1. Cerebrum
2. Cerebellum
3. Brainstem
Term
Name the 3 poles of the brain?
Definition
1. Frontal pole
2. Temporal pole
3. Occipital pole
Term
What are the two components of the cerebrum?
Definition
1. Telencephalon
2. Diencephalon
Term
(T/F) The telencephalon is the largest, most recently evolved portion of the brain
Definition
True
Term
Name the 3 fissures of the cerebrum?
Definition
1. Sagittal fissure/sulcus
2. Horizontal Fissure
3. Lateral fissure
Term
What structures does the sagittal divide?
Definition
The left and right hemispheres of the brain
Term
What structures does the horizontal divide?
Definition
Separates the telencephalon from the cerebellum
Term
What structures does the lateral divide?
Definition
Separates the temporal lobe from the more superior portions of the cerebrum
Term
Name the 4 lobes of the telencephalon?
Definition
1. Frontal
2. Temporal
3. Parietal
4. Occipital
Term
What is the outer covering of the telencephalon?
Definition
The cortex
Term
(T/F) It has low surface area and is barely folded
Definition
False
Term
What gives the cortex its high surface area, and why is this important?
Definition
Gyri (ridges) and sulci (valleys) create folds; important because more area of cortex = more brain power
Term
Name the 7 sulci of the telencephalon
Definition
1. Central sulcus
2. Pre-central
3. Post-central
4. Parieto-occipital
5. Calcarine
6. Cingulate
7. Callosal
Term
What lobe is the central sulcus associated with/which lobes does it divide?
Definition
Separates frontal and parietal lobes
Term
What lobe is the precentral sulcus associated with/which lobes does it divide?
Definition
Within the frontal lobe (more anterior)
Term
What lobe is the postcentral sulcus associated with/which lobes does it divide?
Definition
Within the parietal lobe (more posterior)
Term
What lobe is the pareito-occipital sulcus associated with/which lobes does it divide?
Definition
Separates parietal and occipital
Term
What lobe is the calcarine sulcus associated with/which lobes does it divide?
Definition
Occipital lobe
Term
What lobe is the cingulate sulcus associated with/which lobes does it divide?
Definition
Above the cingulate gyrus
Term
What lobe is the callosal sulcus associated with/which lobes does it divide?
Definition
Above corpus callosum
Term
Name the 3 main gyri of the telencephalon?
Definition
1. Precentral
2. Post central
3. Cingulate
Term
What does the precentral gyrus contain?
Definition
The motor cortex
Term
What does the postcentral gyrus contain?
Definition
The sensory cortex
Term
What is the insula (insular cortex) and where is it found?
Definition
Portion of the cortex found within the lateral fissure
Term
What is the insula believed to be involved in?
Definition
Consciousness and emotion/regulation of body homeostasis
Term
(T/F) The Diencephalon is located central to the telencephalon at the base of the cerebrum
Definition
True
Term
Name the 4 components of the diencephalon?
Definition
1. Thalamus
2. Hypothalamus
3. Subthalamus
4. Epithalamus
Term
What is the function of the thalamus? Where is it located?
Definition
It is the main sensory nucleus; on either side of the third ventricle
Term
(T/F) It involves sensory input from every sense
Definition
False, it does not handle smell
Term
What is the function of the hypothalamus?
Definition
Hormone creation for certain hormones
Term
Where is it found?
Definition
Below the thalamus and connected to the pituitary gland
Term
Where is the subthalamus located?
Definition
Small nucleus located below the thal
Term
Where is the epithalamus located?
Definition
Small nucleus behind the thal
Term
What is found in the grey matter of the cerebrum?
Definition
All of the cell bodies of the neurons
Term
Where is the grey matter in the cerebrum found?
Definition
1. Cortex
2. Basal ganglia
Term
(T/F) The ganglia deep in the cerebrum are mostly involved in motor control
Definition
True
Term
Name the 3 nuclei that make up the basal ganglia
Definition
1. Lentiform
2. Caudate
3. Amygdala
Term
What two things make up the lentiform nucleus, and which is located more medially?
Definition
Putamen and the Globus Pallidusl the GP is more medial
Term
What is the amygdala involved in?
Definition
Emotional control
Term
(T/F) The basal ganglia are located inferiorly to the internal capsule and the thalamus
Definition
False, they are on the same horizontal level
Term
Name the 3 types of fibers that make up the cerebral white matter? What is the most important white matter in the brain?
Definition
1. Association fibres
2. Commusural fibres
3. Projection fibres

- corpus callosum = most important
Term
What is the function of association fibers?
Definition
They allow communication within one hemisphere
Term
(T/F) All association fibers are the same length
Definition
False, they can be long, intermediate or short
Term
What do the shortest association fibers connect?
Definition
Adjacent gyri
Term
What is the function of commisural fibers?
Definition
Communication between the hemispheres
Term
Name the 3 sets of commisural fibers in the brain? Which is the largest, and which is the smallest?
Definition
1. Corpus Callosum (largest)
2. Anterior commisure
3. Posterior commisure (smallest)
Term
Where is the corpus callosum located?
Definition
Below the saggital fissure, runs from the frontal lobe to the occipital lobe
Term
What is the function of the CC?
Definition
Communication between hemispheres
Term
Name the 3 parts, and which is located where?
Definition
1. Genu (anterior)
2. Body
3. Splenium
Term
What is the function of projection fibers?
Definition
Communicate between different levels of the CNS
Term
(T/F) They are confined to the cerebrum
Definition
False
Term
(T/F) The pyramidal tract is an example of this
Definition
True
Term
Describe the pathway of the pyramidal tract?
Definition
Starts at motor cortex, through CC, through cerebral peduncles, through pons and medulla down to spinal cord
Term
Name the 3 components of the brainstem
Definition
1. Midbrain (mesencephalon)
2. Pons
3. Medulla (oblongata)
Term
What is found on the anterior of the midbrain? Which is the fiber bundle
Definition
1. Cerebral peduncles (fiber bundle)
2. Mamillary bodies
Term
What is found on the posterior of the midbrain? Are these fiber bundles?
Definition
The superior and inferior colliculi (little bumps); yes
Term
What is the apparent function of the pons?
Definition
Appears to bridge the cerebellar hemispheres?
Term
What exists posteriorly to the pons?
Definition
4th ventricle and the cerebellum
Term
What is the structure below the pons?
Definition
Medulla
Term
What two structures are on the anterior of the medulla? Are they paired
Definition
1. Pyramids
2. Olives
- Yes; two pyramids and two olives
Term
Which set of structures is more medial?
Definition
The pyramids
Term
(T/F) The cerebellum is strictly restricted to the brainstem
Definition
False
Term
What is the cerebellum responsible for?
Definition
Coordination
Term
What serves as the main connection between the cerebellum and the brainstem?
Definition
The middle cerebellar peduncles
Term
What is the structure that is located below he medulla?
Definition
The spinal cord
Term
What are the boundaries of the spinal cord?
Definition
Starts at the foramen magnum, ends at the level of L1/L2
Term
How many sets of spinal nerves are there?
Definition
32
Term
What is the conus medullaris? What level is it at?
Definition
The pointy end of the spinal cord; at L1/L2
Term
How do the spinal nerves leave the vertebral column?
Definition
Through intervertebral foramen between each vert.
Term
What attaches the conus medullaries to the sacrum?
Definition
The filum terminale
Term
What other structure is located below L2? Why does it exist?
Definition
The cauda equina; the cord is shorter than the column, so spinal nerves need to travel downward to exit at the proper location
Term
Name the 2 enlargements of the cord?
Definition
1. Cervical
2. Lumbar
Term
What causes the cervical enlargement? The lumbar?
Definition
Cerv: nerves leaving to join the brachial plexus and innervate the arms
Lumb: nerves leaving to the lower limbs exit here
Term
Where is grey matter located in the SC?
Definition
Interiorly, in an H shaped pattern
Term
What is the function of the anterior horns of the grey matter?
Definition
Motor function
Term
What is the function of the posterior horns of the grey matter?
Definition
Sensory function
Term
What attaches to the anterior horn? The posterior horn?
Definition
Anterior root and posterior root, respectively
Term
(T/F) All levels of the spinal cord have an intermediate horn
Definition
False, only levels between T1 and L2
Term
What is the function of this intermediate horn?
Definition
Serves the sympathetic nervous system
Term
What is the anterior groove of the SC called? The posterior groove? Which is deeper/larger?
Definition
Anterior sulcus (deeper/larger); posterior groove
Term
How is the white matter arranged around the grey matter in the SC?
Definition
Into 3 columns (funiculi)
Term
Name the 3 funiculi?
Definition
1. Anterior
2. Lateral
3. Posterior
Term
(T/F) The CNS is essentially hollow
Definition
True
Term
What are the fluid filled chambers of the CNS called? What is in them?
Definition
Ventricles; CSF
Term
(T/F) The ventricles of the brain are continuous with the central canal of the spinal cord
Definition
True
Term
Name the 3 ventricles, and how many of each are there?
Definition
1. Lateral (ventricles 1 and 2, 1 for each hemisphere)
2. 3rd
3. 4th
Term
Name the 4 parts of the lateral ventricles, and which lobe each is assoicated with?
Definition
1. Anterior horn (frontal)
2. Posterior horn (occipital)
3. Inferior horn (temporal)
4. Body (parietal)
Term
What is the atrium of the lateral ventricle?
Definition
The portion of the lateral ventricle body that connects the posterior and inferior horns
Term
What do the lateral ventricles contain? (2)
Definition
1. Choroid plexuses 2. CSF
Term
What is the function of the foramina of monro?
Definition
Connects the lateral ventricles to the 3rd ventricle
Term
Describe the third ventricle
Definition
Thin and sagitally oriented
Term
Where is it located?
Definition
Between the two halves of the thalamus
Term
What is the function of the aqueduct of sylvius?
Definition
Connects the 3rd and 4th ventricles; passes through midbrain
Term
What is the shape of the 4th ventricle? Where is it located?
Definition
Diamond shaped; in between the pons/medulla (anterior) and the cerebellum (posterior)
Term
(T/F) The 4th vent is continuous with the central canal of the spinal cord
Definition
True
Term
What are the 3 foramina in the 4th ventricle?
Definition
1. Foramen of Luschka (2)
2. Foramen of Magendie
Term
What is the function of these foramina?
Definition
CSF travels from here into the subarachnoid space
Term
What is the meninges?
Definition
The CT that covers the CNS
Term
Name the 3 layers of the meninges from outermost to innermost?
Definition
1. Dura mater
2. Arachnoid mater
3. Pia mater
Term
(T/F) The dura is multilayered and the layer located closest to the skull
Definition
True
Term
What is the falx cerebri?
Definition
The invagination of the dura mater into the sagittal fissure
Term
What is the tentorium cerebelli?
Definition
The invagination of the dura mater into the horizontal fissure
Term
What are the chanels within the dira called?
Definition
The Dural Venous Sinuses
Term
How far down the SC does the dura mater extend?
Definition
To the level of the sacrum
Term
(T/F) Although the dura is the closest layer to the bone, it has no actual attachment to the bone
Definition
False, it is firmly attached to the skull
Term
What is the epidural space?
Definition
The fat filled space between the dura and the vertebral column
Term
(T/F) the arachnoid matter is much thicker than the dura
Definition
False, it is much thinner
Term
What is contained within this layer?
Definition
Blood vessels
Term
(T/F) Unlike the dura, the arachnoid mater extends a short way into the sulci as well as invaginating the fissures
Definition
True
Term
(T/F) The arachnoid is always firmly attached to the pia
Definition
False, it is only attached loosely to the pia in the cranial vault
Term
What does this attachment create? What circulates here?
Definition
The subarachnoid space, where CSF circulates
Term
Where is the arachnoid attached to the dura? Is that the only attachment of the arachnoid in this instance?
Definition
In the VC
Term
What attaches the arachnoid and pia mater in the VC?
Definition
Denticulate ligaments
Term
(T/F) The pia is firmly attached to the superficial cortex and outer surface of the spinal cord, so it is essentially the outer layer of the CNS
Definition
True
Term
What structure produces CSF? What is it produced from?
Definition
The choroid plexuses; filtered arterial blood
Term
(T/F) It has both metabolic and protective functions
Definition
True
Term
Where does the CSF circulate in the CNS? How does it get here?
Definition
- Subarachnoid space
- Travels through the ventricular system, then through the foramina of luschka and magendie in the 4th ventricle
Term
What structure allows CSF passage into the sinuses?
Definition
Arachnoid villi
Term
What forms these structures?
Definition
Where the arachnoid mater penetrates through the dura layer that extends into the saggital fissure
Term
Where are the arachnoid villi located?
Definition
Superior sagittal sinus
Term
(T/F) The sinuses only contain CSF
Definition
False, they contain venous blood as well
Term
What blood vessel do the sinuses eventually enter into?
Definition
The internal jugular vein
Term
What are cisterns?
Definition
Large openings in the subarachnoid space
Term
Which is the largest cistern? What is its significance?
Definition
- Lumbar cistern (L2 level)
- Most common place for physicians to sample CSF
Term
What are the two sources of blood for the brain?
Definition
1. Carotid arteries
2. Vertebral arteries
Term
How does the carotid artery enter the skull?
Definition
Carotid canal
Term
How do the vertebral arteries enter?
Definition
Foramen magnum
Term
What happens to the vertebral arteries once they enter the skull?
Definition
Then anastomose (join)
Term
What artery does this form? Where is this artery found?
Definition
The basilar artery; runs up the pons
Term
What vessels does the basilar artery turn into?
Definition
It bifurcates into the posterior cerebral arteries
Term
What vessels give rise to the two anterior cerebelar arteries and the middle cerebral arteries? Where does this vessel split into the anterior/middle vessels?
Definition
The internal carotids; level of sella turcica
Term
What vessel connects the two anterior arteries?
Definition
The anterior connecting artery
Term
What vessel(s) connect(s) the middle and posterior cerebellar arteries?
Definition
The posterior communicating (2x)
Term
Where is the circle of willis formed?
Definition
Around the pituitary gland
Term
What do the anterior and posterior arteries supply?
Definition
The sagittal surface of the brain and the periphery of the outer cortex
Term
What does the middle artery supply?
Definition
The centre of the brain
Term
How does it do this?
Definition
By traveling through the lateral fissure
Term
What vessels supply the cerebellum?
Definition
Superior and inferior cerebellar arteries
Term
What vessels supply the spinal cord?
Definition
The vertebral arteries
Term
Describe venous drainage of the brain?
Definition
Blood drains into the dural venous sinuses, and then into the internal jugular
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