Term
Mendel's law of independent assortment |
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Definition
allele pairs separate independently during the formation of gametes---traits are transmitted to offspring independently of one another |
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Term
mendel's law of segregation |
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Definition
allele pairs separate or segregate during gamete formation, and randomly unite at fertilization. |
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Term
4 main concepts of mendels law of segregation |
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Definition
1. genes can exist in more than 1 form 2. organisms inherit 2 alternate forms of a gene for each trait (one from each parent)...called alleles 3. when gametes (sex cells) are produced, allele pairs separate or segragate leaving them with a single allele for each trait. ie sex cells contain only 1/2 the compliment of genes 4. dominant always masks recessive |
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Term
relationship genes and proteins |
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Definition
inherited diseases reflect a patient's inability to make a particular enzyme aka inborn errors of metabolism |
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Term
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Definition
deoxyribonucleic acid -consists of 4 bases (amount of bases always the same in dna) -polynucleotide, organized into chromosomes base+sugar=nucleoside nucleoside+phosphate=nucleotide |
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Term
bacterial genetic elements |
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Definition
-chromosomes: 1. most often one 2. circular 3. between 0.5-10 million base pairs long 4. organized in a nucleoid -plasmids (extra chromosomal dna...replicate by themselves) 1. some have several plasmids, some have none. 2. usually circular 3. btwn 1 thousand and 1.5 million base pairs 4. copy number between 1 and 1,000 5. carrying genes for antibiotic resistance 6. toxins 7. carrying info for conjugation 8. not usually required for cell survival 9. cloning |
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Definition
eukaryotic cell: around 10,000 replication origins bacteris: 1-5 origins -one strand follows each daughter cell |
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Definition
-dna carries genetic info -thru transcription the info is copied to rna -thru translation, the info in rna is translated into a polypeptide chain/protein |
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Definition
genetic info in the nucleus -proteins are synthesized on ribosomes in cytoplasm -alternative of non-specialized ribosomes that translate unstable rna's are called messenger rna |
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Definition
-transcription factors bind to promoter region -promoters important regulatory domains -rna polymerase is recruited w the help of sigma factors -dna helix is unwound -promoter is cleared -transcription begins |
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Term
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Definition
-rna polymerase copies the template strand into a single stranded mrna ==makes an exact copy of the coding strand -mrna contain the same bases as dna except using uracil in place of thymine |
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Definition
-rho-independent: transcription stops when the rna molecule forms a g-c rich hairpin loop, followed by a string of u's -rho-dependent: the protein rho destabilizes the interaction between mrna and template and releases the new mrna -3 codons are called "stop codons" they code for no amino acid and all protein coding regions end in a stop codon -when the ribosome reaches a stop codon, release factor proteins bind and cause the ribosome, the mrna and the new polypeptide to separate |
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Definition
requires the insertion or deletion of 3 bases |
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Definition
-structural rna molecules that transfer the amino acid to the ribosome based on the correct codon use |
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Term
amino acids & peptide bonds |
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Definition
*there are 20 amino acids-theyre the building blocks to make all proteins -they all have an amino group (nh2-) on one end, and an acid group (cooh) on the other end -attached to the central carbon is an R group, which differs for each of the different amino acids. -when polypeptides are synthesized, the acid group of one amino acid is attached to the amino group of the next amino acid, forming a peptide bond |
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Definition
-mrna binds thru the ribosomal binding site |
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Definition
changes in the dna sequence that may be passed along to future generations |
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Definition
a single base substitution -silent mutation |
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Definition
injection of dna by phages (bacterial viruses) |
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Definition
cell-mediated transfer of host genetic material |
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Definition
donor dna fragments and binds to surface of bacteria -dna is imported and becomes single-stranded -single stranded dna incorporates into host chromosome |
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