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Cell Structure
Important words and concepts
35
Biology
Graduate
09/17/2014

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Term
functional organization of the body
Definition
Cells, tissues(epithelium, muscle, connective, nervous) organs (stomach, heart, lung, skin), organ sys (digestive, repiratory, excretory), you and me DAWG! Ie a humanbeing broseph! Go CERTS!
Term
how to cells vary generally speaking
Definition
Size/Shape, internal structure, life span/rate of self renewal
Term
Glycocalyx
Definition
complex of carbohydrates on the external surgace of the plasma membrane which are covalently attached to proteins or lipids
Term
endocytosis
Definition
internalizations of small membrain vesicles less then one micron from the plasma memrane
Term
pinocytosis
Definition
"cell drinking" uptake of fluid by a continuous process also provides a mechanism for membrane recycling
Term
Receptor mediated endocytosis
Definition
requires receptor ligand binding for vesicle formation and internalization, ligand bound receptor initiates requitement of adaptin which initiates formation of clathin coat responsible for invagination, dynamin pinches membrane completeing internalization
Term
exocytosis and the two types
Definition
fusion of cytoplasmic vesicles with the plasma membrane and release of the vesicle contents 1)regulated requires extracellular signal for vesicle fusion and released regulated secrtion ie hormones and schtuff! 2) constituative exocytosis- secretion is a continous process
Term
transcytosis
Definition
uptake of material on the basal or apical side is take from one of the cell and released on the other
Term
nuclear envelope
Definition
composed of two unit membranes inner and out which are seperated by parinuclear space, membranes space are contunous with ER. Outer layer has ribosomes, nuclear pores are large highly regulatory protein (octet) structures that cross both membranes
Term
nuclear lamina
Definition
intermediate filament on the inner nuclear membrane which provide support for nuclear membrane
Term
nucleolus, nucleolar organizing centers (aka?), pars fibrosa, pars granulosa
Definition
nucleolus: site of ribosomal RNA syn and intial ribo subunit assebly, NOC aka fibrillar centers: are pale staining regions containing DNA encoding rRNA, Pars fibrosa: electron dense fribrillar region compased of ribo RNA transcripts, Pars granulosa: granular appearing region compased of maturing ribo partiples
Term
Chromatin
Definition
DNA + protein but mostly histone protein, chromatin exist in transciptinally active and inative states
Term
euchromatin
Definition
transciptionally active dispersed light staining
Term
heterochromatin
Definition
transciptionally inavtive condensed dark staining
Term
nucleoplasm
Definition
cytoplasmo of the nucleous
Term
Rough ER, breifly describe and types of proteins made here
Definition
falttened membranes sacs that are continuous with nuclear membrane, proteins for secretion, lysosomal proteins, proteins that function in the ER and golgi, some membrane lipds/proteins
Term
Smooth ER breigly describe form and function with the types of things synthesized
Definition
tubular memranous structure contuous with endoplasmic reticulum, no ribos, responsible for syn: triglycerides, cholesterol, steroid hormones, functions to detox, and calcium storage
Term
unboud ribo what kind of proteins do the syn
Definition
cytoplasmic prots, mitochdial prots peroxisomes and nuclear proteins
Term
fates of golgi vescles
Definition
fuse with plasma membrane there by delivering membrane lipids and proteins, form secretory vescles,
Term
zymogen granuales
Definition
secretory vevsciles with enzymes
Term
peroxisomes
Definition
single membrane vesicles with oxidative enzymes important roles in detox
Term
2 common forms of pigment
Definition
Lipofuscin pigment: indigestible residues of oxidation prouctions of lipid catabolism, melanin, primary syn by melanocytes
Term
cytoskeleton function and 3 primary components
Definition
gives shape support for the cell provides cell motility and facilitates intracellular transport microfilament, intermediate filaments, microtubes
Term
Microfilaments size function make up
Definition
4-6nm filaments composed of actin function in cell movement and extensio nof cellular processses
Term
intermediate fillament size function make up
Definition
structurally and chemically heterogenous, 8-10nm filaments which are cell type specific function in structual support
Term
microtobules size function make up inaddition to structures commonly seen in the cell
Definition
18-20 nm tubules composed of β and α tubulin multiple functions structures include Centriole, basal body, axome mitotic spindle
Term
centriole
Definition
short rod structure compsed of 9 sets of three microtubles centroles cocur in pairs (diplosome) need the nucleus function in navigating chromosome to opposing sides during mitosis
Term
basal body
Definition
same structure as the centriole located at the base of cilia and flagell providing support and MT's seving as the source of core for the stuctures 9 pairs of 2 MT's with 2 in the center
Term
axomes
Definition
forms the core of cilia and flagell and provides for the movement made of MT's
Term
mitotic spindle
Definition
individual MT's which extend from the centrioles to the kinetochore of chromatid durig cell division
Term
interphase
Definition
Longest phase of the cycle.
Includes Go, G1, S, G2
Term
prophase
Definition
Replicated DNA condenses into chromosome pairs. These chromatids are attached at the centromere.
Term
metaphase
Definition
•Centrosomes at the opposite poles of the cell. •Sister chromatids align at the equatorial plate.
Term
anaphase
Definition
Sister chromatids separate, each moving towards an opposite pole.
Term
telophase
Definition
Cleavage furrow forms, and separation occurs with a contractile ring of actin and myosin filaments. We see the nucleolus reforming and the ultimate division of the two daughter cells.
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