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CELL CYCLE/MITOSIS & CELL DIVISION
n/a
65
Biology
Undergraduate 1
11/15/2011

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Term
what are chromatids?
Definition
attached chromosomes
Term
what is a centromere?
Definition
attaches two chromosomes
Term
what are homologous pairs (homologues)?
Definition
carry genes for the same traits
Term
what is a diploid?
Definition
have a homologous chromosome PAIR (2n)
Term
what is a haploid?
Definition
cells that don’t have homologous pairs (n)
Term
what is karyotyping?
Definition
putting homologous pairs together
Term
what is the Cell Cycle?
Definition
the “life span” of a cell
Term
Are the time-frames of all cell types the same?
Definition
NO
Term
what are the 3 periods of INTERPHASE?
Definition
- Gap 1 period
- Synthesis period
- Gap 2 period
Term
What happens in the Gap 1 phase of interphase?
Definition
cell growth before dna is duplicated
Term
what happens in the synthesis period of interphase?
Definition
DNA synthesis
Term
what happens in the Gap 2 period of interphase?
Definition
further growth & preparation for mitosis
Term
Will you see chromosomes in the interphase period?
Definition
No, you will only see chromatin
Term
Mitosis is basically what?
Definition
cell division
Term
4 stages of mitosis?
Definition
- prophase
- metaphase
- anaphase
- telophase
Term
what 3 things happen in prophase?
Definition
- chromosomes condense and become visible
- microtubules start to assemble to form spindle fibers
- cell membrane begins to break up
Term
what 3 things happen in metaphase?
Definition
- sister chromatids become oriented toward opposite ends of cell
- spindle fibers attach to chromosomes
- line up on equator
Term
which stage of mitosis is rapid?
Definition
anaphase
Term
what 2 things happen in anaphase?
Definition
- sister chromatids separate and move to opposite poles
- cell elongates
Term
what 3 things happen in anaphase?
Definition
- begins when chromosomes reach opposite ends of cell
- chromosomes de-condense
- nucleaur envelope forms
Term
What is cytokinesis?
Definition
physical division of cell
Term
What period usually overlaps anaphase and telophase?
Definition
cytokinesis
Term
how is cytokinesis different in plants and animals?
Definition
- animals form cleavage furrow
- plants form a cell plate
Term
in what kinds of cells does mitosis/cytokinesis occur?
Definition
somatic (body cells of animals
Term
what are the 3 reasons that mitosis/cytokinesis occurs?
Definition
o for growth of embryo
o for body growth
o for repair & replacement
Term
Mitosis/cytokinesis is limited to what kind of organisms?
Definition
eukaryotes
Term
what is the result of mitosis/cytokinesis?
Definition
2 cells with the same number of chromosomes as the original cell
Term
what are telomeres?
Definition
region of repetitive DNA sequences at the end of a chromosome
Term
what is the function of telomeres?
Definition
protect the end of the chromosome from deterioration or from fusion with neighboring chromosomes
Term
what is telomerase and what does it do?
Definition
- It is an enzyme that adds/replenishes telomeres on the DNA
Term
How do telomeres and telomerase relate to the process of mitosis/cytokinesis?
Definition
- telomeres are dissolved in cell division
- telomerase allows for further cell division by replenishing/adding telomeres when they are depleted
Term
Where does Meiosis occur?
Definition
in germ cells (testes/ovaries)
Term
what is the one purpose of meiosis?
Definition
to form gametes (egg/ovum and sperm)
Term
During meiosis, the chromosomes number will be reduced by how much?
Definition
by 1/2
Term
Does meiosis have one or two cell divisions?
Definition
2
Term
Germ cells have _______ number of chromosomes
Definition
dilpoid
Term
how many autosome chromosomes do humans have?
Definition
22
Term
how many pairs of sex chromosomes do humans have?
Definition
1
Term
male genotype?
Definition
XY
Term
female genotype?
Definition
XX
Term
what are the two meiotic divisions?
Definition
- meiosis I
- meiosis II
Term
What are the 4 stages of Meiosis I?
Definition
- prophase I
- metaphase I
- anaphase I
- telophase I
Term
What are the 4 stages of Meiosis II?
Definition
- prophase II
- metaphase II
- anaphase II
- telophase II
Term
what is the function of Meiosis I?
Definition
separation of homologous pairs
Term
what is the function of Meiosis II?
Definition
separations of sister chromatids
Term
what 4 things happen in prophase I?
Definition
- Individual replicated chromosomes become visible
- Spindle fibers form
- Nuclear membrane disintegrates
- homologous chromosomes pair with each other
Term
In prophase I, what happens when the homologous chromosomes pair together?
Definition
- synapse/crossing over occurs
Term
what is the result of synapse and crossing over?
Definition
genetic variability
Term
what happens in metaphase I?
Definition
- homologous pairs line up on equator of cell
Term
what happens in anaphase I?
Definition
homologous pairs separate and move toward opposite poles
Term
what 2 things happen in telophase I?
Definition
- spindle fibers disintegrate
- cytokinesis begins
Term
what is the result of Meiosis I?
Definition
2 haploid cells
Term
After meiosis, what is the number of chromosomes compared to the original cell?
Definition
1/2 the number of chromosomes
Term
what happens between meiosis I and II?
Definition
INTERPHASE
Term
what 2 things happen in prophase II?
Definition
- chromosomes condense
- sister chromatids still attached at centromeres
Term
what happens in metaphase II?
Definition
-chromosomes line up on equator with each sister chromatid oriented toward a pole
Term
what 2 things happen during anaphase II?
Definition
- chromosomes separate
– sister chromatids move to opposite poles
Term
what happens in telophase II?
Definition
-4 daughter nuclei form
Term
what is the overall result o Meiosis?
Definition
4 daughter cells with haploid number of chromosomes
Term
what is spermatogenesis?
Definition
formation of sperm
Term
what is oogenesis?
Definition
formation of ovum or egg
Term
what are 3 types of chromosomal abnormalities?
Definition
- deletion
- translocation
- non-disjunction
Term
explain the chromosomal abnormality: deletions
Definition
A portion of the chromosome is missing or deleted
Term
explain the chromosomal abnormality: translocations
Definition
When a portion of one chromosome is transferred to another chromosome
Term
Explain the chromosomal abnormality: translocations
Definition
failure of chromosome pairs to separate properly during meiosis stage 1 or stage 2
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