Shared Flashcard Set

Details

Cell Bio: Cell Signaling
N/A
16
Biology
Undergraduate 3
05/09/2009

Additional Biology Flashcards

 


 

Cards

Term
Endocrine
Definition
Long distance, blood stream
Term
Paracrine
Definition
Short distance, extracellular space
Term
Autocrine
Definition
Self-signal (same cell)
Term
GPCR: extracellular terminus?
Definition
N-terminus
Term
GPCR: extracellular terminus?
Definition
C-terminus
Term
Kd
Definition
Concentration of ligand at which 1/2 of its receptors are occupied
Term
Trimeric G-Protein: GTPase Activity in which unit?
Definition
alpha
Term
G-Protein: GTP Bound
Definition
On state
Term
G-Protein: GDP Bound
Definition
Off state
Term
GEF
Definition
Guanine nucleotide-exchange factor. Catalyze dissocation of GDP, enabling GTP to bind to G protein.
Term
cAMP Mediated Glycogen Metabolism: Increaed cAMP leads to?
Definition
Less glycogen, more glucose.
Term
cAMP Mediated Glycogen Metabolism: Decreased cAMP leads to?
Definition
Less glucose, more glycogen.
Term
Activation of GPCR that activates Gαs. Higher or lower levels of cAMP?
Definition
Increased cAMP.
Term
Activation of GPCR that activates Gαi. Higher or lower levels of cAMP?
Definition
Lower levels of cAMP
Term
Binding of this ligand leads to reduction in # of cell-surface receptors and reduced sensitivity to hormone?
Definition
β-arrestin
Term
Activation of Gαo or Gαq subunits activate?
Definition
Phospholipase C
Supporting users have an ad free experience!