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CD660 Module 5 Flash Cards
Study Terms
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Graduate
09/06/2012

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Term
Ectoderm
Definition
• Ectoderm is the outermost layer and it gives rise to:
• the entire nervous system (PNS, CNS)
• all hair, nails and skin (epidermis)
• sensory epithelium of the eye, ear and nose
• the pharynx
• the dental enamel
Term
Mesoderm
Definition
• Mesoderm is the middle layer and it gives rise to:
• muscle
• connective tissue [primordial embryonic connective tissue] is also
called mesenchyme
• bone and cartilage
• blood vessels
Note: CL+CP results from a disturbance to mesoderm
Term
Endoderm
Definition
• Endoderm is the innermost layer and it gives rise to:
• the linings of the digestive and respiratory tracts
Term
Primordia/Primordium
Definition
The term
primordial means the original tissue from which something is formed,
derived.

The anterior neuropore, which is the anterior opening
of the developing neural tube. This neural tube is the primordium for
the central canal of the spinal cord.
Term
Branchial Apparatus:
Buccopharyngeal Membrane
(aka Orophyaryngeal membrane)
Definition
the oropharyngeal membrane separates the
stomodeum (the primitive mouth opening) from the primitive
pharynx; this membrane ruptures at about 4 weeks gestation,
allowing communication between the primitive gut and the
amniotic cavity
Term
Stomodeum
Definition
Primitive mouth opening
Term
Frontonasal Process
Definition
The frontonasal process differentiates to form the nasolateral and
nasomedial processes.
Term
Nasal Placode
Definition
The nasal placode is a thickening of the primordial ectoderm, around which the
lateral nasal and medial nasal processes develop.
[
Term
Otic Pit
Definition
The otic pit will migrate medially and become the external auditory meatus
Term
Intermaxillary Segment
Definition
The medial nasal (aka nasomedial) processes fuse in midline
and form the primary palate; the primary palate is also called
the intermaxillary segment, the premaxilla, or the pre-palate; it
gives rise to:
*the philtrum and mid-portion of the upper lip
*the four incisor teeth and
*associated maxillary alveolus
Term
Maxillary Process
Definition
the maxillary processes form the bulk of the [lateral parts of the] upper
lip;
the upper lip is formed by the merging of the maxillary processes with
the nasomedial processes;
Term
Mandibular Process
Definition
The mandibular processes differentiate to form the mandible, the anterior 2/3 of the tongue** [aka the oral tongue] and the lower lip

** the posterior part of the tongue comes from the 2nd through 4th branchial arches

structures derived from the mandibular process are innervated
by the mandibular division of CN V, the trigeminal nerve
Term
Nasal Pit
Definition
The nasal pit will migrate medially and become the nostril. The nasal pit is part of the frontonasal process
Term
Naso-optic Furrow
Definition
The naso-optic furrow is where the maxillary and lateral nasal processes meet, and therefore the site of oblique clefting.
Term
Branchial Arches
Definition
Four branchial arches can be seen on the surface of the head and neck area
in the 4 week-old embryo;they are separated from each other by branchial grooves
• branchial arches are numbered in a cephalad to caudal direction as
arches 1 through 6; the branchial arches support the lateral walls of the anterior foregut, primitive pharynx; the pharyngeal pouches evaginate from the primitive pharynx;Note: Each branchial arch differentiates and gives rise to muscles, cartilages,
bones, and blood vessels; certain cranial nerves [CNs] (V, VII, IX, X)
grow from the brain into specific branchial arches. In fact, CNs V, VII, IX and X are associated with arches 1, 2, 3, and 4, respectively. (see pg. 30 of lecture 5 for detailed photo and explanation of arches.
Term
Primary Palate
Definition
If we draw an imaginary wedge from the incisor teeth back to the incisive foramen, that segment of prolabium, incisor teeth, alveolus and palate is the primary palate.the medial nasal (aka nasomedial) processes fuse in midline and form the primary palate; the primary palate is also called the intermaxillary segment, the premaxilla, or the pre-palate. for the primary palate, the direction of closure is downward and
forward with the lip closing last; therefore, the mildest form of
primary palate clefting is a lip notch, often considered a microform of
clefting
Term
Secondary Palate
Definition
secondary palate closure starts between the 7th and 8th weeks and is completed by the 12th week of gestation; it includes:
• the hard palate posterior to the incisive foramen
• the soft palate and
• the uvula
The secondary palate develops from the two (2) lateral palatine processes,
which are shelf-like outgrowths of the maxillary processes.
Term
Secondary Palate Closure
Definition
See pg. 16-19 of module 5. Too much info for this card!
Term
Macrostomia
Definition
Lateral clefts [aka transverse clefts] occur because of lack of fusion
between maxillary and mandibular processes; they are often seen as a
component of a syndrome, especially the spectrum of “hemifacial
microsomia.” Clinically, the mouth appears large due to the
lateral/labial corner extension which can be unilateral or bilateral; and
the lateral facial cleft is, therefore, often labeled as macrostomia [note
the relationship between stomodeum and macrostomia]
Term
Congenital
Definition
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