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CD markers
CD markers
23
Medical
Graduate
10/30/2010

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Cards

Term
CD1
Definition
Category: Antigen presentation
Function: Presentation of glycolipids to NKT cells
Expression: Dendritic cells
Term
CD3
Definition
Category: Antigen presentation
Function: Pan-T cell marker: Mediates signaling of the TCR
Expression: T cells
Term
CD4
Definition
Category: Antigen presentation
Co-receptor
Function: Marker for helper T cells; Co-receptor for MHC class II-restricted cells- co-activates with TCR-CD3; Binding site for HIV
Expression: T cells
Term
CD8
Definition
Category: Antigen presentation
Function: Marker for killer/suppressor T cells; Co-receptor for MHC class I-restricted cells
Expression: T cells
Term
CD11
Definition
Caegory: Adhesion molecule
Function: α chain of the β2 integrin family
Expression: Leukocytes
Term
CD14
Definition
Category: Differentiation antigen
Function: Non-signaling component of the LPS receptor
Exression: Monocytes, Macrophages
Term
CD18
Definition
Category: Adhesion molecule
Function: β chain of the β2 integrin family; adhesion to endothelium
Expression: Leukocytes
Term
CD19
Definition
Category: Co-receptor
Function: Signal transducer on B cells
Expression: B cells
Term
CD20
Definition
Category: Complement receptor
Function: Chain of the CR2 receptor
Expression: B cells
Term
CD21
Definition
Category: Complement receptor
Function: Chain of the CR2 receptor
Expression: B cells
Term
CD25
Definition
Category: Cytokine receptor
Function: α chain of the IL-2 receptor - binds IL-2
Expression: B cells
Term
CD28
Definition
Category: Co-receptor
Function: Co-receptor on T cell that binds B7
Expression: T cells
Term
CD32
Definition
Category: Ig Binding receptor
Function: Binds Ig-Ag complexes
Expression: Macrophages
Term
CD34
Definition
Category: none specified
Function: Hematopoietic stem cell marker
Expression: Stem cells
Term
CD40
Definition
Category: Co-receptor
Function:Co-receptor on B cells
Expression: B cells
Term
CD45
Definition
Category: Enzyme
Function: Tyrosine phosphatase of T and Expression: B cells
Many cells
Term
Definition
Category: Complement receptor
Function: Membrane Decay Accelerating Factor (DAF)
Expression: Many cells
Term
CD59
Definition
Category: Complement receptor
Function: Membrane receptor of MAC assembly
Expression: Many cells
Term
CD62L
Definition
Category: Homing receptor
Function: Homing to lymph nodes
Expression: B and T cells
Term
CD80/86
Definition
Category: Ligands
Function: Also known as B7-1/B7-2. These molecules are ligands for the CD28 co-receptor.
Expression: none specified
Term
CD120
Definition
Category: Death-inducing receptor
Function: TNF-induced apoptosis
Expression: Many cells
Term
CD154
Definition
Category: Co-receptor
Function: Ligand on T cells for CD40
Expression: T cells
Term
CD240D
Definition
Category: Blood group markers
Function: Major Rh antigen
Expression: Erythrocytes
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