Term
4 types of obstructive disorders? |
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Definition
Adhesions, Intessusception, Volvus, Hernias |
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Term
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Definition
Defect in peritoneal wall |
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Term
If you have had surgery, infxn or peritoneal inflammation which of the obs d/o do you prob have? |
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Definition
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Term
What obs d/o is MC in kids esp after a rotovirus infxn? |
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Definition
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Term
For intussusception what is the tx for kids and for adults? |
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Definition
Kids: barium enema Adults: Surgery |
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Term
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Definition
Redudant sigmoid colon, then cecum, then sml bowel, then stomach |
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Term
What are poss complications of obstructive d/o? |
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Definition
Ischemia, obstruction, infarcation |
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Term
What are causes of Hemorrhoids? |
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Definition
Venous statis of preg, Potal HTN, straining at stool in constipated pts |
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Term
Ext hemorrhoids involve what? Internal hemorrhoids? |
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Definition
Ext: inf hemorrhoidal plexus, below anorectal line
Inf: Superior hemorrhoidal plexus, in distal rectum |
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Term
What is assoc w low fiber diets? |
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Definition
Sigmoid diverticulitis, hemorrhoids, colonic adenoma and colonic adenocarcinoma |
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Term
Where do diverticulae occur? |
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Definition
Where nerves and & BVs penetrate colonic wall |
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Term
Sml Bowel Adenomas are MC located |
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Definition
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Term
What is more common small bowel adenomas or colon adenomas? |
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Definition
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Term
Carinoid tumors arise from |
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Definition
Neuroendeocrine cells that release hormones (5HT) |
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Term
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Definition
Periumbilical pain, N/V, dilated loops of bowel |
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Term
When do you get Carcinoid s/o and what are the Sx? |
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Definition
When the Carcinoid tumor has metastasize so the products enter the systemic ciruclation. Sx: Flushing, diarrhea, colicky abd pain bronchospasm, sweating. |
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Term
What is the most impt feature of carcinoid tumor? |
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Definition
Where it is located! Anything above the ligament of trietz or below colon (+appendix) are better Px. Bt ligament of trietz & rectum, they may grow large, X, be aggressive or mets. |
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Term
Syaptophysin, chrmogranin A |
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Definition
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Term
If you have a tumor in appendix what is the most likely cause? |
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Definition
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Term
What can cause pseudomyxoma peritoneii? |
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Definition
Mucinous cystadenocarcinoma in the appendix |
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Term
If you see a 65yo w X small polyps in the L colon what is the most likely cause? |
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Definition
Hyperpastic Polps of the colon. |
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Term
Serrated surface archietecture w/ mature goblet & absorptive cells |
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Definition
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Term
Pulmonary AVM, age and what dz? |
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Definition
<5yo w Juvenile Type harmartomatous polyp |
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Term
3yo w a polyp causing rectal bleeding/proplase |
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Definition
Juvenile type Harmartomatous polyp |
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Term
Which non neoplastic polyp of the colon has cystically dilated gland filled w mucin & inflamm debris? |
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Definition
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Term
Which non neoplastic polyp of the colon has large polyp w a lobulated contour and Arborhizing archituecture? |
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Definition
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Term
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Definition
Cowden s/o or Bannayan Rubulacaba Riley s/o |
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Term
Pt w marcocephaly, benign skin tumors & colon polpys has what? Inc risk of what? |
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Definition
Cowden s/o. Inc risk of breast CA, endomeatrial CA, follicular thyroid CA. NOT inc risk of GI CA! |
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Term
Pt has colon polpys and mental deficiences, what do they have? |
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Definition
Bannayan-Rubulcaba-Riley s/o |
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Term
>50 you pt w GI polpys. ON PE you also see splitting and atrophy of the nails, hair loss, and hyper/hypo pigmentation of the skin; what do they have? |
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Definition
Cronkite-Canada s/o. 50% fatal. They might also have diarrhea, weakness, abd pain, wt loss. |
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Term
What type of colonic adenoma can secrete lg amt of protein & K? |
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Definition
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Term
Does the architecture types of colonic adenoma give any Px info? |
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Definition
Not really, just the assoc w size. The larger the adenoma (usu villous) the more likley you will get colon CA. |
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Term
Do intramucosal adenocarcinoma spread? |
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Definition
Not really, they will just invade further into the wall. There are no lymphatic channels so not likley to spread far. |
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Term
what is the MC malignancy of the GI tract? |
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Definition
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Term
Why are colonic adenoCA very firm? |
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Definition
They have a strong desmoplastic response when they invade into intestinal wall. IF they produce mucin that is a bad px |
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Term
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Definition
EBV and immuno compromised. |
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Term
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Definition
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Term
What s/o iss assoc with prophlatic colectomy bc there is a 100% chance of colon CA? |
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Definition
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Term
FAP+tumors of skull/long bones, epidermal cysts, desmoid tumors, thryoid tumors, dental abn? |
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Definition
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Term
FAP + Medulloblastoma (MC) or gliobastoma |
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Definition
Turcot s/o
Medulloblastoma assoc w FAP mutation
Glioblastoma assoc w DNA repiar gene mutations |
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Term
A 40 year old is dx w colon CA; but they have no polps and its in R colon. |
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Definition
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Term
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Definition
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Term
What is the MC site for colonic adenoCA |
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Definition
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Term
There are two types of hereditary polyps in the GI tract that have an AR/AD assoc? which ones are they? |
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Definition
AD Cowden s/o, Bannayan-Rubulcaba-Riley, AFP |
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Term
What polyp dz is mostly in the L colon? Mostly in the rectum? Mostly in the small intestine? |
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Definition
L colon= Hyperplastic polyps of the colon Rectum= Juvenile type harmartomatous Small intestine= Puetz Jughers |
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Term
Salt and pepper chromatin |
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Definition
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