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Cartilage, from top down: perichondrium (fibrous layer and then cellular layer), matrix (lacunae with chondrocytes) |
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Fibrocartilage in vertebral disc |
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Bracket: perichondrium (fibrous, cellular layers)
Arrow: chondrocytes and lacunae |
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Elastic cartilage (pinna) |
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Elastic cartilage (more opaque, pinna) |
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Fibrocartilage (top to bottom arrows: nucleus, collagen, fibers, lacuna) |
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Joint! Hyaline cartilage on both sides of synovial fluid, bone marrow in the bone |
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Perichondrium --> chondrogenic cell --> chondroblast --> chondrocytes |
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Arrow (black): Howship's Lacunae, or resorption bays |
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Circled: osteon
Top arrow: Volkmann's canal
Bottom arrow: Haversian canal |
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Compact bone on left, cancellous bone right |
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Lacunae between lamellae of matrix, canaliculi between the lacunae |
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Left to right: matrix, osteoid, osteoblast |
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Left to right: OBs, OCs, osteocyte, mesenchyme, bone matrix, osteoid |
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Mesenchymal stem cells
Osteoprogenitors
OBs
Osteocytes
OCs |
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Top to bottom: osteocyte, osteoprogenitors and osteoblasts, haversian canal
Circle: osteon |
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Top to bottom: odontoblasts, odontocytes, odontoclasts |
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Blue: collagen fibrils
Purple: osteoblasts
Red: matrix vesicles |
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Heterogenous Nucleation, collagen fibers with gap regions in between |
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Left to right: inflammation, soft callus formation, hard callus formation, remodeling |
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Intramembranous ossification |
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Top to bottom: zones of... resting, proliferation, hypertrophy/maturation, calcification, ossification |
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Top to bottom: primary center (calcified cartilage), periosteal bud |
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B3 knockout in bone, shows more trabecular bone |
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Src knockout bone, arrow pointing out trabecular bone increase |
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Green arrow: ruffled border! |
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Formation of sealing ring during bone resorption |
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