Term
| three implications of frank starling relationship |
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Definition
1- CONTROL OF END SYSTOLIC VOLUME (PREVENTS ESV FROM INCREASING THEREFORE PREVENT CLOTTING)
2- MATCHING OF LV AND RV OUTPUT
3- PREVENTION OF RISE IN VENOUS PRESSURE
(PREVENT BLOOD FROM BACKING UP IN VEINS/CAPS... BC VR= PRELOAD
AND VR DETERMINES EDV |
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Term
| HOW TO INCREASE FORCE OF CONTRACTION |
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Definition
| INCREASE EDV AND FILL MORE! |
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Term
3 WAYS TO ALTER MYOFILAMENTS
BIGGER TRIGGER
BIGGER RESPONSE |
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Definition
CHANGE AFFINITY OF TROPONIN FOR CA++
INCREASE AMOUNT OF CA++ RELEASED MORE TROPONIN SATURATION
INCREASE Pi RELEASE THUS INCREASING CYCLING RATE AND INCREASING SR PUMP ACTIVITY THUS AIDING IN FASTER RELAXATION |
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Term
| HOW DOES PARASYM INHIBIT SYMPATHETIC CASCADE |
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Definition
INHIBIT PRODUCTION OF cAMP BY ADENYLATE CYCLASE.
(M-ACH--> Gi----> AC ) |
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Term
| AFTERLOAD AFFECTS STROKE VOLUME |
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Definition
AFTERLOAD IS DUE TO MABP
IF YOU ASSUME EQUAL CONTRACTILITY AND EDV... HIGH MABP DECREASES STROKE VOLUME.
SO... HIGH MABP REDUCES CARDIAC OUTPUT ULTIMATELY. |
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