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cardiovascular drugs
pharm...
36
Dentistry
Undergraduate 3
10/22/2014

Additional Dentistry Flashcards

 


 

Cards

Term
what is the # 1 killer in the us
Definition
Heart disease is # 1 killer
Term
cardiovascular contraindications for DH care
Definition

MI in last 6 months

unstable or recent angina

uncontrolled congestive heart failure

uncontrolled arryhtmias

uncontrolled hypertension

 

Infective endocarditis

pace makers (caution)

Term
why limit vasoconstricor for cardiac patient
Definition
due to endogenous epinephrine made already
Term
cardiac glycosides
Definition

digoxin, lanoxin,digitalis

 

used for CHF and to slow heart beat and make beat more effective.

Term
what happens if left side of heart fails
Definition

blood backed into pulmonary artery

lungs fill with blood

Term
right side CHF
Definition

right ventricle fails and is unable to move blood into pulmonary

 

dypsnea

cyanosis

high HR

cough

PITTING EDEMA/pedal edema(swelling of ankles

Term
toxic effects of digitalis glycosides
Definition

 nausea

arrythmia

headache/drowsiness/vision(neurological)

increased salivation

 

when mixed with sympathomimetrics increase in arrythmias can happen

Term
what can increase digoxin levels
Definition
tetracycline and erythromycin can increase digoxin levels by 10%
Term
arrythmias are caused by
Definition

myocardial anoxia-not enough oxygen to heart

arteriosclerosis-narrowing and hardening of blood vessels

heart block

Term
rythm of heart or electrical pattern
Definition

SA

AV

bundle of his

perkinje fibers

cardiac muscle

Term
ectopic foci
Definition
rythm of heart is messed up
Term
examples of anti arrythmics
Definition

verapamil/calan(isoptin)

 

nifedipine(procardia, adalat)

 

propanolol

 

cartizem

 

cause gingival enlargement

Term
what would lidocaine be used for as far as arrthmias
Definition
lidocaine for ventricular arrythmias
Term
antianginal drugs
Definition

amyl nitrite

nitroglycerine

nitrek

beta blockers(propranolol)

 

work to reduce workload on heart

Term
what does nitroglycerine do?
Definition

vasodilates

 

releases free nitrite ion and nitric oxide

 

relaxes vascular smooth muscle

Term
what pretreatments might you use on a angina pt:?
Definition
Nitrous oxide or bensodiazepine to relax pt
Term
pre hypertension
Definition
120-139/80-89
Term
steps for controlling hypertension
Definition

1. lifestyle changes

2. CCB , diaretics(try 1st), adrenergic beta blockers

3. mix agents, adrenergic beta blockers, vasodilators

4. mix 2-3 drugs

Term
thiazide diuretics: hydrocholorothizide
Definition

diuretic agent

reduce extracellular fluid and volume and changes in sodium and calcium concentrations reduce senstitivity to sans.

Term
adverse reactions to thiazides
Definition

hypokalemia-low potassium

hyperglycemia-high blood sugar

hyperlipdemia-high cholesterol

hypercalciemia-high calcium

anorexia

hyperuricemia-increase in uric salts(GOUT!)

Term
tegretol
Definition
treat trigeminal neuralgia, but can make calcium channel blockers toxic in system if pt is taking them.
Term
ace inhibitors
Definition

drugs that act on sodium and water

 

block vasoconstriction which lowers BP

Term
adverse reactions of ace inhibitors
Definition

DRY COUGH

 

taste disturbance

rash, photosensitiviy

diabetic, neuropathy

tetrogenicity: do not give to pregnant women

Term
antihyperlipidemic agents
Definition

statin drugs (atorvastatin simvastatin

 

for high cholesterol

 

inhibit enzyme for cholesterol synthesis

Term
ldl's should be less than
Definition
100mg/dl
Term
HDLs should be
Definition
less than 200 mg/dl
Term
normal triglyceride level
Definition
less than 150 mg/dl
Term
adverse effects of antihyperlidemics
Definition

GI probs

 

impotence

 

muscle weakness

 

elevated liver enzymes

 

destruction of muscle tissue leading to renal failure

 

 

Term

contraindications for statin drugs

 

simvastatin(Zocor)

Atorvastatin (lipitor)

tricor

zetia

vytorin

Definition

renal/liver disease

 

existing muscle weakness

 

pregnancy, breast feeding, children

Term
how do alpha adrenergic blocking agents help men with prostate problems
Definition
blocks resistence in urethra
Term
what can reduce effectiveness of ACE inhibitors
Definition
NSAIDS my reduce effectiveness of ACE inhibitors
Term
what should you know about drug interactions with alpha adrenergic blocking agents
Definition

nsaids may reduce antihypersensive effect of alpha blockers

 

epinephrine may cause sever hypotension and reflex tachycardia(DONT USE IT) with adrenergic blocking agents.

 

 

Term
examples of antihypertensives
Definition

catapress(clonidine) causes xerostomia

 

aldomet

 

reserpine

 

hydralazine

Term
side effects of antihypertensives
Definition

xerostomia

 

dysguesia

 

gingival enlargement

 

orthostatic hypertension

 

constipation

 

CNS sedation

Term
niacin/nicotinic acid
Definition

lowers triglycerides and limits secretions of VLDLS

 

may be used in combo with statin drugs

Term
niacin/nicotinic acid side effects
Definition

GI upset

 

fatigue

 

skin flushing, itching

 

hot flashes(can cause non-compliance)

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