Term
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Definition
Narrowed or constricted orifice |
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Term
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Definition
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Term
Which is the most common form of stenosis? |
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Definition
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Term
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Definition
Aortic valve doesn't fully open which decreases flow from the heart |
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Term
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Definition
SOB Angina Syncope Palpitations |
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Term
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Definition
Valve leaflets or cusps do not shut o r close completely |
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Term
What valves can cause regurgitation? |
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Definition
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Term
Mitral regurgitation can be caused by? |
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Definition
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Term
What is the most common valve disorder in the US? |
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Definition
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Term
Mitral Valve Prolapse (MVP) |
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Definition
Valve doesn't close properly during systole |
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Term
True or False: Most cases of MVP are asymptomatic? |
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Definition
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Term
MVP may pose an increased risk of? |
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Definition
Infective endocarditis Stroke (cardiac source) Sudden death |
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Term
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Definition
Palpitations Angina SOB Fatigue |
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Term
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Definition
Systemic inflammatory disease |
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Term
Rheumatic Fever is a delayed reaction to? |
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Definition
Group A beta hemolytic streptococcus |
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Term
Rheumatic fever is inflammation of? |
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Definition
Joints Skin Nervous system HEART |
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Term
How does rheumatic fever cause rheumatic heart disease? |
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Definition
Causes scarring and deformity of cardiac structures |
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Term
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Definition
General term for infection and inflammation of endocardium |
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Term
Where do you most commonly see infective endocarditis? |
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Definition
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Term
Causes of infective endocarditis |
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Definition
Bacteria (most common) Viruses, fungi rickettsiae and parasites |
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Term
What is infective endocarditis commonly associated with? |
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Definition
Prosthetic valves Indwelling catheters Heart surgery |
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Term
When you have a pathogen that enters the bloodstream and causes bacteremia, you will get growth of vegetation that leads to? |
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Definition
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Term
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Definition
Localized manifestation related to another disease |
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Term
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Definition
Acute inflammation of pericardium |
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Term
What causes acute pericarditis? |
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Definition
Virus (hepatitis, influenza, HIV) Trauma |
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Term
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Definition
fluid accumulation in pericardial cavity; can occur in all types of pericarditis |
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Term
Constrictive/Restrictive Pericarditis |
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Definition
loss of pericardial fluid due to scaring and fibrosis of tissue; layers adhere |
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Term
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Definition
Disease that affects the myocardium Many causes |
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Term
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Definition
Dilated Hypertrophic Restrictive |
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Term
Types of Hypertrophic cardiomyopathy |
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Definition
Asymmetric septal hypertrophy Hypertensive or valvular hypertrophic cardiomyopathy |
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Term
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Definition
Heart is unable to generate adequate cardiac output |
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Term
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Definition
inadequate tissue perfusion or increased diastolic filling pressure of left ventricle, increasing pulmonary capillary pressures |
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Term
Primary risk factors for heart failure? |
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Definition
Ischemic heart disease Hypertension |
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Term
What is another name for left heart failure? |
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Definition
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Term
What are 2 types of left heart failure |
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Definition
Systolic heart failure Diastolic heart failure |
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Term
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Definition
Inability of the left ventricle to generate adequate cardiac output to perfuse tissues |
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Term
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Definition
Pulmonary congestion despite normal stroke volume and cardiac output |
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Term
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Definition
Inability of right ventricle e to provide adequate blood flow into pulmonary circulation |
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Term
Right heart failure causes an increase in? |
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Definition
left ventricular filling pressure that reflects back to pulmonary circulation |
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Term
What causes right heart failure |
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Definition
Diffuse hypoxic pulmonary disease (COPD, CF, and ARDS |
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Term
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Definition
Stroke Volume X Heart Rate |
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Term
What affects stroke volume? |
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Definition
Preload Afterload Contractility |
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Term
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Definition
End systolic volume Venous return |
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Term
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Definition
Aortic pressure Aortic vavular function |
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Term
What affects contractility |
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Definition
End diastolic volume Sympathetic stimulation Myocardial oxygen supply |
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Term
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Definition
Volume of blood flowing through systemic or pulmonary circulation |
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Term
How is cardiac output measured? |
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Definition
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Term
What is another name for cardiac output |
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Definition
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Term
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Definition
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Term
Ejection fraction formula |
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Definition
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Term
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Definition
Volume and pressure in ventricle at the end of diastole |
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Term
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Definition
Volume of blood in the ventricle AFTER atrial contraction AFTER ventricular filling (end diastole) |
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Term
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Definition
Stretch of ventricular muscle fibers |
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Term
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Definition
Describes relationship between wall tension and radius |
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Term
Law of Laplace states that contractile force within a chamber depends on? |
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Definition
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Term
According to Law of Laplace, smaller chambers and thicker chamber walls equals? |
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Definition
Increased contraction force |
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Term
Frank-Starling Law of the Heart describes? |
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Definition
-Length-tension relationship to myocardial contractility -Mechanism that allows for right and left ventricles to maintain equal minute outputs despite stroke (beat) output variations |
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Term
In Frank-Starling Law, increased preload increases? |
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Definition
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Term
In Frank-Starling Law, myocardial stretch determines? |
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Definition
Force of myocardial contraction -Thus with more stretch = increased force of contraction -Excessive stretch causes decreased stroke volume |
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Term
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Definition
The pressure the ventricular muscles must generate to overcome the higher pressure in the aorta to get the blood out of the heart |
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Term
What is the index of afterload? |
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Definition
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Term
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Definition
load or resistance that the ventricle must eject its volume of blood against during a contraction |
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Term
Resistance is produced by? |
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Definition
Volume of blood and constriction of blood vessels within the system |
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Term
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Definition
-Change in tension at a given resting fiber length -Ability of the heart muscle to shorten |
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Term
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Definition
Thin actin filaments slide of thick myosin filaments |
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Term
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Definition
Chemicals that affect contractility |
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Term
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Definition
epi norepinephrine thyroid hormone dopamine |
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Term
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Definition
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Term
Myocardial contractility is affected by? |
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Definition
Oxygen and carbon dioxide levels |
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Term
Cardiovascular control center of cardiac output |
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Definition
Main = medulla in brainstem Secondary = hypothalamus, cerebral cortex, thalamus, and connecting neurons |
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Term
Baroreceptor reflex and cardiac output |
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Definition
-Blood pressure and heart rate changes -Tissue pressure receptor or pressoreceptors |
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Term
Where are baroreceptors located? |
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Definition
Aortic arch Carotid arteries |
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Term
Atrial receptors and cardiac output |
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Definition
-Receptors that influence heart rate |
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Term
Where are atrial receptors found? |
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Definition
Right and left atria chemoreceptors |
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Term
What does distension of atria stimulate? |
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Definition
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Term
Atrial receptors stimulate what? |
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Definition
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Term
Hormones and biochemicals that affect cardiac output? |
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Definition
Norepinephrine Epinephrine Thyroid hormones |
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Term
What does norepinephrine do? |
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Definition
Increases heart rate Enhances myocardial contractility Constricts the blood vessels |
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Term
What does epinephrine do? |
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Definition
Dilate vessels of liver and skeletal muscle Increased myocardial contractility |
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Term
What do thyroid hormones do? |
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Definition
Enhance sympathetic activity Increase cardiac output |
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Term
What factors affect blood flow? |
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Definition
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Term
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Definition
Force exerted on a liquid (i.e. blood) per unit area |
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Term
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Definition
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Term
What contributes to resistance |
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Definition
Diameter and length of the blood vessels |
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Term
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Definition
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Term
Factors Affecting Blood Flow |
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Definition
Velocity Laminar vs. turbulent flow Vascular compliance |
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