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Cardiovascular Ch 29-31
Slides 46-69
86
Nursing
Graduate
02/26/2012

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Term
Stenosis
Definition
Narrowed or constricted orifice
Term
2 types of stenosis
Definition
Aortic
Mitral
Term
Which is the most common form of stenosis?
Definition
Aortic
Term
Aortic Stenosis
Definition
Aortic valve doesn't fully open which decreases flow from the heart
Term
Aortic Stenosis Symptoms
Definition
SOB
Angina
Syncope
Palpitations
Term
Regurgitation
Definition
Valve leaflets or cusps do not shut o r close completely
Term
What valves can cause regurgitation?
Definition
Aortic
Mitral
Tricuspid
Term
Mitral regurgitation can be caused by?
Definition
Mitral Valve Prolapse
Term
What is the most common valve disorder in the US?
Definition
Mitral Valve Prolapse
Term
Mitral Valve Prolapse (MVP)
Definition
Valve doesn't close properly during systole
Term
True or False: Most cases of MVP are asymptomatic?
Definition
True
Term
MVP may pose an increased risk of?
Definition
Infective endocarditis
Stroke (cardiac source)
Sudden death
Term
Symptoms of MVP
Definition
Palpitations
Angina
SOB
Fatigue
Term
Rheumatic Fever
Definition
Systemic inflammatory disease
Term
Rheumatic Fever is a delayed reaction to?
Definition
Group A beta hemolytic streptococcus
Term
Rheumatic fever is inflammation of?
Definition
Joints
Skin
Nervous system
HEART
Term
How does rheumatic fever cause rheumatic heart disease?
Definition
Causes scarring and deformity of cardiac structures
Term
Infective Endocarditis
Definition
General term for infection and inflammation of endocardium
Term
Where do you most commonly see infective endocarditis?
Definition
Cardiac valves
Term
Causes of infective endocarditis
Definition
Bacteria (most common)
Viruses, fungi
rickettsiae and parasites
Term
What is infective endocarditis commonly associated with?
Definition
Prosthetic valves
Indwelling catheters
Heart surgery
Term
When you have a pathogen that enters the bloodstream and causes bacteremia, you will get growth of vegetation that leads to?
Definition
Infective endocarditis
Term
Pericardial disease
Definition
Localized manifestation related to another disease
Term
Acute pericarditis
Definition
Acute inflammation of pericardium
Term
What causes acute pericarditis?
Definition
Virus (hepatitis, influenza, HIV)
Trauma
Term
Pericardial effusion
Definition
fluid accumulation in pericardial cavity; can occur in all types of pericarditis
Term
Constrictive/Restrictive Pericarditis
Definition
loss of pericardial fluid due to scaring and fibrosis of tissue; layers adhere
Term
Cardiomyopathy
Definition
Disease that affects the myocardium
Many causes
Term
Types of cardiomyopathy
Definition
Dilated
Hypertrophic
Restrictive
Term
Types of Hypertrophic cardiomyopathy
Definition
Asymmetric septal hypertrophy
Hypertensive or valvular hypertrophic cardiomyopathy
Term
Heart Failure
Definition
Heart is unable to generate adequate cardiac output
Term
Heart failure causes?
Definition
inadequate tissue perfusion or increased diastolic filling pressure of left ventricle, increasing pulmonary capillary pressures
Term
Primary risk factors for heart failure?
Definition
Ischemic heart disease
Hypertension
Term
What is another name for left heart failure?
Definition
Congestive heart failure
Term
What are 2 types of left heart failure
Definition
Systolic heart failure
Diastolic heart failure
Term
Systolic heart failure
Definition
Inability of the left ventricle to generate adequate cardiac output to perfuse tissues
Term
Diastolic heart failure
Definition
Pulmonary congestion despite normal stroke volume and cardiac output
Term
Right Heart failure
Definition
Inability of right ventricle e to provide adequate blood flow into pulmonary circulation
Term
Right heart failure causes an increase in?
Definition
left ventricular filling pressure that reflects back to pulmonary circulation
Term
What causes right heart failure
Definition
Diffuse hypoxic pulmonary disease (COPD, CF, and ARDS
Term
Cardiac Output formula
Definition
Stroke Volume X Heart Rate
Term
What affects stroke volume?
Definition
Preload
Afterload
Contractility
Term
What affects preload
Definition
End systolic volume
Venous return
Term
What affects afterload
Definition
Aortic pressure
Aortic vavular function
Term
What affects contractility
Definition
End diastolic volume
Sympathetic stimulation
Myocardial oxygen supply
Term
Cardiac Output
Definition
Volume of blood flowing through systemic or pulmonary circulation
Term
How is cardiac output measured?
Definition
Liters per minute
Term
What is another name for cardiac output
Definition
Minute volume
Term
Ejection fraction
Definition
Amount ejected per beat
Term
Ejection fraction formula
Definition
Stroke volume/EDV
Term
Preload
Definition
Volume and pressure in ventricle at the end of diastole
Term
Preload refers to?
Definition
Volume of blood in the ventricle AFTER
atrial contraction
AFTER
ventricular filling (end diastole)
Term
Preload relates to?
Definition
Stretch of ventricular muscle fibers
Term
Law of Laplace
Definition
Describes relationship between wall tension and radius
Term
Law of Laplace states that contractile force within a chamber depends on?
Definition
Wall thickness
Radius
Term
According to Law of Laplace, smaller chambers and thicker chamber walls equals?
Definition
Increased contraction force
Term
Frank-Starling Law of the Heart describes?
Definition
-Length-tension relationship to myocardial contractility
-Mechanism that allows for right and left ventricles to maintain equal minute outputs despite stroke (beat) output variations
Term
In Frank-Starling Law, increased preload increases?
Definition
Stroke Volume
Term
In Frank-Starling Law, myocardial stretch determines?
Definition
Force of myocardial contraction
-Thus with more stretch = increased force of contraction
-Excessive stretch causes decreased stroke volume
Term
Afterload
Definition
The pressure the ventricular muscles must generate to overcome the higher pressure in the aorta to get the blood out of the heart
Term
What is the index of afterload?
Definition
Aortic systolic pressure
Term
Afterload refers to?
Definition
load or resistance that the ventricle must eject its volume of blood against during a contraction
Term
Resistance is produced by?
Definition
Volume of blood and constriction of blood vessels within the system
Term
Myocardial contractility
Definition
-Change in tension at a given resting fiber length
-Ability of the heart muscle to shorten
Term
Cross bridge theory
Definition
Thin actin filaments slide of thick myosin filaments
Term
Inotropic agents
Definition
Chemicals that affect contractility
Term
Positive Inotropes
Definition
epi
norepinephrine
thyroid hormone
dopamine
Term
Negative Inotropes
Definition
Acetylcholine
Term
Myocardial contractility is affected by?
Definition
Oxygen and carbon dioxide levels
Term
Cardiovascular control center of cardiac output
Definition
Main = medulla in brainstem
Secondary = hypothalamus, cerebral cortex, thalamus, and connecting neurons
Term
Baroreceptor reflex and cardiac output
Definition
-Blood pressure and heart rate changes
-Tissue pressure receptor or pressoreceptors
Term
Where are baroreceptors located?
Definition
Aortic arch
Carotid arteries
Term
Atrial receptors and cardiac output
Definition
-Receptors that influence heart rate
Term
Where are atrial receptors found?
Definition
Right and left atria chemoreceptors
Term
What does distension of atria stimulate?
Definition
Atrial receptors
Term
Atrial receptors stimulate what?
Definition
Bainbridge reflex
Term
Hormones and biochemicals that affect cardiac output?
Definition
Norepinephrine
Epinephrine
Thyroid hormones
Term
What does norepinephrine do?
Definition
Increases heart rate
Enhances myocardial contractility
Constricts the blood vessels
Term
What does epinephrine do?
Definition
Dilate vessels of liver and skeletal muscle
Increased myocardial contractility
Term
What do thyroid hormones do?
Definition
Enhance sympathetic activity
Increase cardiac output
Term
What factors affect blood flow?
Definition
Pressure
Resistance
Term
Pressure
Definition
Force exerted on a liquid (i.e. blood) per unit area
Term
Resistance
Definition
Opposition to force
Term
What contributes to resistance
Definition
Diameter and length of the blood vessels
Term
Poiseuille Law
Definition
Viscosity
Radius
Length
Term
Factors Affecting Blood Flow
Definition
Velocity
Laminar vs. turbulent flow
Vascular compliance
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