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Cardiology
Dyslipidemias
32
Medical
Graduate
09/19/2010

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Cards

Term
~20%
Definition
A person with DM has what percent of 10 year risk factor for CHD?
Term
Primary prevention
Definition
What kind of prevention refers to intervention in patients without detected CHD?
Term
Secondary prevention
Definition
What prevention refers to intervention in patients who manifest CHD or have a CHD equivalent ?
Term
Primary Prevention
Definition

Reducing cholesterol levels REDUCES the risk of CHD (less MIs, less angina, less CABGs), proportionate to the reduction in LDL and the increase in HDL.

What kind of prevention is this?

Term

men >35

 

Women >45

Definition
Routine testing for the USPSTF for dyslipidemias occurs at what age for men and women?
Term
20
Definition
Screening for the ATP III starts at what age?
Term
Total cholesterol and HDL
Definition
What cholesterol tests do not need to be fasting?
Term
Fasting lipid Panel
Definition
If a pt comes in with a tuberous xanthoma, what test would you order?
Term
perform a 10-yr risk assessment
Definition
What should you do next for a pt with 2+ risk factors?
Term
>20%
Definition
What is considered high for a 10-yr risk of CAD event?
Term
treating high LDL levels
Definition
Treating what is the primary target of therapy?
Term
TG
Definition
Elevated what is an independent risk factor for CAD?
Term
<100
Definition
What is the LDL goal for someone with CHD or CHD risk equivalents?
Term
<130
Definition
What is the LDL goal for someone with 2+ risk factors?
Term
<160
Definition
What is the LDL goal for someone with zero to one risk factors?
Term
<7% of total calories
Definition
For a TLC diet, what percentage should saturated fats make up of the diet?
Term
<200 mg/day
Definition
In a TLC diet, how much should dietary cholesterol be per day?
Term
Statins
Definition
What is the first line of drugs used to treat dyslipidemias?
Term
Statins
Definition
Myopathy and Myalgias are side effects of what class of drugs?
Term
Statins
Definition
 What is the Drug of choice for elevated LDL cholesterol based on safety and efficacy?
Term
HMG-CoA reductase
Definition
Statins competitively inhibit the ________ enzyme that catalyzes the rate-limiting step in cholesterol biosynthesis.
Term
Bile Acid Sequestrants
Definition
What type of drugs reduce LDL and raise HDL and may raise TG, but not as good as Statins?
Term
Bile acid sequestrants
Definition
What class of drugs Interrupt bild acid reabsorption requiring bile acid synthesis from cholesterol?
Term
Bile acid sequestrants
Definition
 Drug of choice to lower cholesterol in children, women of child bearing age.
Term
Nicotinic Acid (Niacin)
Definition
What type of drugs lower LDL and TG and also increase HDL?
Term
Nicotinic Acid
Definition
What drug has side effects that include flushing, hyperglycemia, hyperuricemia and hepatotoxicity?
Term
Fibric Acid
Definition
Which drugs may lower or raise LDL-C but also lower TG significantly?
Term
Ezetimibe
Definition
What drug Selectively inhibits intestinal absorption of cholesterol and related phytosterols?
Term
Ezetimibe
Definition
What drug reduces LDL, TG and Apolipoprotein B?
Term
Ezetimibe
Definition
What drug does not reduce Coronary events when given by itself?
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