Term
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Definition
| showed no difference in all cause mortality and nonfatal MIs between pts with STABLE ANGINA treated with MAXIMAL MEDICAL THERAPY ALONE vs MEDICAL THERAPY WITH PCI. (there is no difference between the two) |
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Term
| PRECOMBAT TRIAL and SYNTAX TRIAL |
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Definition
| shown PTCA with stenting MAY be as good as CABG even in pts with left main coronary artery disease |
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Term
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Definition
shoed that in USA (unstable angina) and NSTEMI, risj of death, MI, or recurrent angina was LOWER IN the ENOXAPARIN GROUP at 14 days, 30 days, and one year.
(although unfractionated heparin may still be used if the pt is to be stented right away bc it has a much lower half life) |
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Term
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Definition
pts with prior history of MI were randomized to TREATMENT WITH STATINS and placebo.
The STATIN GROUP HAD A. . .
- REDUCED RISK OF DEATH BY 24%,
- REDUCED RISK OF STROKE (by31%)
- REDUCTION in need for CABG or angioplasty (by 27%) |
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Term
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Definition
| showed that the B-blocker CARVADEDILOL redcues risk of death in pts WITH POST-MI LV DYSFUNCTION |
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Term
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Definition
Heart Outcomes Prevention Evaluation
showed that the ACE inhbitor RAMIPRIL redcues mortality, MI, stroke, and renal disease in a broad range of pts with high risk cardiovascular disease. |
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Term
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Definition
| showed that PTCA reduces mortality more than t-PA |
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Term
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Definition
| showed that SPIRONOLACTONE redcues morbidity and mortality in pts with CLASS III and CLASS IV HEART FAILURE. (it is contraindicated in renal failure) |
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Term
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Definition
| compared two B-blockers in thre treatment of CHF and showed that CARVEDILOL led to significant improvement compared to metoprolol. |
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Term
CAST I and CAST II
(Cardiac Arrhythmia Suppression Trial) |
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Definition
| shoed that the USE OF ANTIARRHYTHMIC DRUGS to suppress pvcs after MI INCREASES THE RISK OF DEATH |
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Term
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Definition
| showed the RATE CONTROL is SUPERIOR to rhythm control in TREATMENT OF A-FIB |
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