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Cardiology 3
Infective Endocarditis
30
Medical
Graduate
09/30/2010

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Cards

Term
Infective Endocarditis
Definition
 Localized infection consisting of fibrin, platelets and microorganisms that adhere to cardiac valves or other endothelial surfaces.
Term
Over 50 y/o
Definition
What age group would you expect to see someone with infective endocarditis?
Term
drugs
Definition
A person presents with infective endocarditis that is 29 y/o, what would you expect the epidemiology to be from?
Term
Mitral Valve
Definition
Which valve is most commonly involved in infective endocarditis?
Term
Step Viridans
Definition
If a pt has mitral regurgitation and a fever, what organism would you suspect?
Term
Tricuspid Valve
Definition
Which valve is most commonly involved in drug users with infective endocarditis?
Term

More at risk!

 

 

*along with Rheumatic Fever, Hypertrophic cardiomyopathy, MVP, IVDA, & Immunocompromised pts

Definition
Is a pt with a prosthetic heart valve more or less at risk for Infective endocarditis?
Term

Less at risk

 

*also pacemakers, syphilitic aortitis, ASD, MVP without regurg, and innocent heart murmurs are NOT risk factors

Definition
Is a pt with CAD more or less at risk for IE?
Term
Fever & changing or new murmurs
Definition
What is the main physical findings of a pt with IE?
Term
Osler's Nodes
Definition
What are painful bumps on the fingers and toes caused by IE called?
Term
Roth Spots
Definition
What are Fuzzy spots seen on the retina caused by IE?
Term
Janeway lesions
Definition
What are non-tender spots on the feet and hands caused by IE called?
Term
Streptococci
Definition
What is the most common organism responsible for IE?
Term
Gram Negative bacilli
Definition
What type of organism would you expect to see with a pt with a prosthetic valve or who uses drugs?
Term
Staphylococci
Definition
What organism would you expect to see with a pt with native valve endocarditis?
Term
Strep Viridans
Definition
What organism would you expect to see in a pt with a hx of Rheumatic heart disease?
Term
Staph Aureus OR enterococci
Definition
What organism would you expect to see in a pt with nosocomia endocarditis?
Term
Mixed pathogens: Staph, yeast, fungi
Definition
What organism would you expect to see in a pt who uses drugs?
Term
Strep Pneumonia
Definition
What organism would you expect to see in a pt with a hx of alcoholism?
Term
CHF
Definition
A pt with IE and what other disease needs to be taken to the OR immediately??
Term

2 Major

 

 

 

Definition
How many major criteria are needed for Duke's Criteria?
Term
>12 hours apart
Definition
To be a major criteria for IE, microorganisms from 2 separate blood counts must be taken how many hours apart?
Term
5 Minor Criteria
Definition
How many minor criteria are needed for Duke's criteria?
Term
4-6 weeks
Definition
How long is IV antimicrobial treatment needed for a pt with IE?
Term

PCN-G + Gentamycin

 

 

*for Strep Viridans

Definition
Which two drugs can be put together to give a pt with IE that will only need to be given for 2 weeks?
Term

4 weeks

 

 

*only for strep viridans & UNCOMPLICATED endocarditis

Definition
How long does a pt being treated with only PCN-G need to be treated for?
Term

Ampicillin + Gentamycin

 

 

*Must be in combo!

Definition
For a pt with IE caused by enterococci, what drugs must be given in combination?
Term

Nafcillin OR oxacillin (4-6wks)

+

Gentamycin (1st 5-7days)

Definition
What drugs would you give for a pt with IE caused by Staph. Aureus?
Term
Take anticoagulants
Definition
What does a pt with a mechanical valve replacement have to do for the rest of their lives?
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