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Cardiology 2
*Cardio II MI_ACS and More Examing the Heart
68
Medical
Professional
07/13/2005

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Term
Which Cardiac Meds prolong survival Post MI?
Definition
Beta-blockers./.Carvedilol./.ACE inhib./.ARBs./.ASA
Term
Which Cardiac Meds Prolong Survival in Heart Failure?
Definition
Beta-blockers...Carvedilol ...ACE inhib ...ARBs Amlodipine...Nitrates... Hydralizine Spironolactone...(Add the ANHS and drop the ASA for Post MI survival Meds)
Term
What effect does Nitrates have on 02 demand?
Definition
Decreases myocardial O2 demand.
Term
List meds that decrease O2 myocardial demand.
Definition
Nitrates...Beta Blockers...Calcium Channel Blockers
Term
True or False.....Ventricular tachycardia or fibrillation within 48 hours of an MI imply a worse prognosis.
Definition
FALSE
Term
Conduction disturbances are most common with what type of MI?
Definition
Inferior Wall MI
Term
Which MI is more likely to have a new bundle branch block or high grade AV block?
Definition
Anterior MI
Term
Which MI is more likely to have primary or secondary Type I block (usually temporary)
Definition
Inferior
Term
Which MI is known to have LESS myocardium lost?
Definition
Inferior Wall MI
Term
Which cardiac marker is released most rapidly from injured muscle cells?
Definition
Myoglobin
Term
Which Cardiac Marker peaks in the first 12-24 hours
Definition
CKMB
Term
Which Cardiac Marker is highly specific for an acute MI
Definition
Troponin I (slightly better than T)... Useful for patients who present more than 24-48 hrs out.
Term
What is the best combo for Cardiac Markers?
Definition
Troponin I (or T) and CKMB1
Term
When do you NOT give Clopidogrel?
Definition
If CABG is anticipated.
Term
Name a Platelet GP IIb/IIIa Antagonist
Definition
eptifibatid_(Integrilin)...tirofiban_(Aggrastat)
Term
In patients for whom PCI is planned what agents should be give?
Definition
Eptifibatide or tirofiban should be given, in addition to ASA and heparin (and perhaps clopidogrel), to patients in whom PCI is planned. These agents should be given, in addition to ASA and haparin, in high-risk patients in whom an invasive strategy is NOT planned.
Term
Fibrinolytics should be given within how many hours after the onset of pain?
Definition
6 hours.
Term
ABSOLUTE Contraindications for Fibrinolytic Agents?
Definition
Previous hemorrhagic stroke at ANY time or other cerebrovascular events within 1 year...Intracranial neoplasm...Active internal bleeding...Suspected Aortic dissection.
Term
When is fibrinolytic therapy indicated in patients with Unstable angina or NSTEMI?
Definition
NEVER!!!
Term
Contraindications to Beta Blocker in MI?
Definition
Bradycardia...2nd or 3rd degree block... Hypotension...h/o bronchospasm...pulmonary congestion... but NOT Diabetes.
Term
When should ACE inhibitors be started post MI?
Definition
In anyone with a large MI or an LVEF <40%. The worse the LV function the better response from ACE inhibitors. They should be continued indefinitely.
Term
Summary of Post MI Medications...
Definition
Beta blockers are continued indefinitely.. ASA is continued indefinitely.. ACE inhibitors are continued indefinitely if there is LV dysfunction.. CLOPIDOGRIL is continued for NINE MONTHS... Lipid lowering drugs should be given to bring LDL below 100mg/dl
Term
When is Left Heart Catheterization not accurate?
Definition
When there is valvular stenosis in low output states or with conconmitant regurgitation; the Left Heart Cardiac Catheterization lacks accuracy.
Term
What are the contraindications for Left Heart Catheterization?
Definition
Contraindications are all relative for Left Heart Cath.
Term
How do you measure the PCWP and what value is normal?
Definition
Do a Right heart cath...normal is <12.
Term
PCWP > 12 suggests
Definition
LV Failure
Term
PCWP 15 - 20 causes:
Definition
Dyspnea on Exertion
Term
PCWP 25 - 35 causes:
Definition
Dyspnea at Rest
Term
PCWP > 35 causes:
Definition
Pulmonary Edema
Term
When is a Stress Test + ?
Definition
A Positive Stress Test is at least 1mm of horizontal or downsloping ST depression 80 msec from the J-point.
Term
What is this? Right Heart Cath Pressures:... RA = 18.... PA = 40/30...PCWP = 30....BP = 70/50
Definition
RV infarction
Term
What is this? Right Heart Cath Pressures: ...RA = 18.... PA = 90/32... PCWP = 30... BP = 110/70
Definition
Mitral Stenosis
Term
What is this? Right Heart Cath Pressures: ...RA = 18... PA = 90/32... PCWP = 10.... BP = 110/70
Definition
Pulmonary Htn.
Term
What is this? Right Heart Cath Pressures: ... RA = 18... PA = 32/18 ... PCWP = 17 ... BP = 70/50
Definition
Tamponade (note the equaliation of diastolic pressures) also see this with constrictive pericarditis.
Term
What is this? Right Heart Cath Pressures: ...RA = 4 ... PA = 15/5 .... PCWP = 9 ...BP = 110/70
Definition
This is NORMAL.
Term
What is Pulsus Parvus et Tardus caused by?
Definition
Aortic Stenosis (AS). May not be present in the elderly in spite of severe AS.
Term
A delay in RV emptying causes what change to the S2?
Definition
Fixed Split (Persistently Split) S2
Term
A delay in LV emptying causes what change to S2?
Definition
Paradoxically Split S2.
Term
List four causes of a Fixed or Persistently Split S2.
Definition
PE...PS...RBBB...Extopic LV rhythm
Term
What is this:....Heard in early diastole with rapid passive filling of a stiff ventricle.
Definition
S3
Term
When is S3 normal?
Definition
Children and usually in pregnant women. Abnormal over the age of 40.
Term
What causes a S3?
Definition
TR...MR...AR...(LV or RV) dysfuction.
Term
CONCENTRIC coronary plaques cause what type of Angina?
Definition
STABLE
Term
RUPTURED plaques cause what type of Angina?
Definition
UNstable
Term
What percentage of patients with ischemic ST changes have angina?
Definition
20%
Term
What causes painless ST segment changes on stress testing.
Definition
Silent Myocardial Ischemia and it is caused by inadequate perfusion.
Term
With regard to the prognosis of CAD what is most closely related to Longevity?
Definition
LV function (this is the most powerful risk stratification parameter in all of cardiology)..... Severity of the angina ....Exercise capacity: the duration of exercise on a stress test (measured in METs) is highly predictive of prognosis. Note that none of these parameters requies coronary angiograpy.
Term
When an area of the myocardium has enough perfusion to maintain myocardial viability, but not enough to contract what do you call it?
Definition
Hibernating Myocardium
Term
What Test is the GOLD STANDARD for Hibernating Myocardium?
Definition
Positron Emission Tomography (PET)
Term
What is this? Hypotension, clear lung fields, and elevated JVP (Kussmaul's sign)
Definition
RV infarction....avoid nitrates (preload reducing agents) ...give IV fluids and frequently Dobutamine.
Term
How do you treat STABLE VT?
Definition
Lidocaine bolus of 1.0 - 1.5 mg/kg followed by 2 - 4 mg/min infusion....... Amiodrone 150 mg infused over 5 minutes followed by a constant infusion of 1.0 mg/min for 6 hours.
Term
AV High-grade block is usually seen with:
Definition
Anterior MI (usually infraHisian)
Term
How do you treat a High-grade AV block?
Definition
Temporary pacing. Anterior infarcts which produce new AV block have a very high mortality.
Term
When is valve surgery better than no surgery?
Definition
When the patient is symptomatic at rest.
Term
Which is better Valve Replacement or Repair?
Definition
Repair
Term
What is the best test for mitral valve prostheses function?
Definition
Transesophageal Echo
Term
Areas of the heart with poor uptake of thallium both at rest and exercise indicate what?
Definition
Infarcts or Aneurysms
Term
S3 is abnormal in patients greater than what age?
Definition
40 yo
Term
What type of coronary artery lesions are associated with UNSTABLE ANGINA?
Definition
Irregular, ulcerated plaques
Term
Which Ca. channel-blocker has the most NEGATIVE INOTROPIC effect?
Definition
Diltiazem/Verapamil (this is why they are not used with beta-blockers).
Term
Which does NOT require Heparin: t-PA or streptokinase?
Definition
Streptokinase does NOT NEED HEPARIN TO MAINTAIN VESSEL PATENCY.
Term
How long should elective surgery be delayed after an MI?
Definition
6 months
Term
What percentage of MI patients develop unstable angina within the 1st week after an MI?
Definition
10%
Term
What is the best prognostic factor after an MI?
Definition
Left-ventricular fxn.
Term
List two lifestyle habits and one hormone that INCREASES HDL?
Definition
Exercise...Drinking a little EtOH...and being Female (Estrogen increases HDL)
Term
Does Balloon angioplasty affect survival?
Definition
NO
Term
Infrahisian block
Definition
Type 2 Second degree heart block, also known as Mobitz II heart block is a disease of the distal conduction system. This is also known as Infrahisian block because the level of block is below the bundle of His. Mobitz II heart block is characterized on a surface ECG by a fixed PR interval with a dropped QRS complex after a certain number of P waves. For instance, for every 4 P waves, there are only 3 QRS complexes.
Term
A heart block can be a blockage at any level of the electrical conduction system of the heart. Clinically speaking, most of the important heart blocks are which type?
Definition
Blocks that occur within the sinoatrial node (SA node) are described as SA nodal blocks. Blocks that occur within the atrioventricular node (AV node) are described as AV nodal blocks. Blocks that occur below the AV node are known as infra-Hisian blocks (named after the bundle of His). Clinically speaking, most of the important heart blocks are AV nodal blocks and infrahisian blocks.
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