Term
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Definition
Classification: Parasympatholytic, Anticholinergic, Vagolytic
Mechanism: Via direct vagolytic action enhances SA node Automaticity, AV node Conduction
used for: hemodynamically significant bradyarrhythmias and asystole
to speed up heart
Dose: .5mg alive, 1 mg dead up to 3mg |
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Term
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Definition
Classification: Vasopressor, vasoconstrictor
Mechanism: improves coronary and cerebral perfusion, Peripheral vasoconstrictor, produces favorable redistribution of blood flow during cardiac arrest
Dose: 1 mg every 3-5 min during CPR |
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Term
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Definition
Classification: class 1B antiarrhythmic/ Ventricular antiarhythmic
Mechanism: Decreases automaticity thereby supressing ventricular arrhythmias, elevates the V-fib threshold, mild sodium blockage, reduces the slope of phase four diastolic repolarization
Dose: initial bolus 1-1.5 mg/kg drip
2nd bolus of .5 mg/kg after ten minutes
3rd .5 mg/kg max dose of 3mg
start drip of 2-4 mg/min
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Term
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Definition
Classification: Atrial and Ventricular antiarrhythmic
Mechanisms: Effects Sodium, potassium and Calcium channels, alpha and beta adrenergic blockage, coronary and peripheral vasodilation, lengthens refractory period in cardiac tissue
Dose: 300 mg IV Bolus if dying
otherwise 150mg over 10 min(may be repeated as needed)
max dose 2gm/day |
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Term
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Definition
Type: Ventricular Antiarrhythmic
Mechanism: supresses ventricular ectopy, slows intraventricular conduction
extends phase four of action potential
Dose: 20-30 mg/min up to 17mg/kg
maintenance rate is 1-4mg/min |
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Term
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Definition
Type: Ventricular antiarrhythmic
Mechanisms: reduction in post infarction ventricular arrhythmias, precipitate refractory v-fib, hypomagnesemia can lead to cardiac arrhythmias and sudden cardiac death
Dose: V-fib or V-tach-1-2gm in 100ml NS over 1-2 min
Post MI: loading dose 1-2mg in 100 ml over 5-60 min |
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Term
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Definition
Type: Supraventricular antiarrhythmic
Mechanism: bring heart back to normal rhythm,not useful for all types of irregular heartbeats, slows AV node conduction, terminated PSVT, May be used to test the heart for coronary artery disease, has a half-life of 5 seconds, not a fix for A-fib or A-flutter but a great diagnostic tool
Dose: 6mg over 1-3 sec followed by 20ml flush
12mg over 1-3 sec
12mg over 1-3 sec |
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Term
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Definition
Type: Supraventricular anti-arrhythmic, Calcium channel blocker
Mechanisms: Calcium channel Blocker, Relaxs blood vessels, Vasodilatoreffects due to blockade of Ca channels and alpha receptors, decreases inotropy
Dose: initial 2.5 - 5.0 mg IV over 2 min
repeat dose 5 -10 mg 15-30 min until max of 20mg |
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Term
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Definition
Type: Supraventricular Antiarrhythmic, Ca channel blocker
Mechanism: fewer hemodynamic effects than verapamil, slows conduction and prolongs refractoriness in AV node
Dose: .25 mg/kg over 2 min
followed by maintenance infusion of 5-15mg titrated to desired heart rate |
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Term
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Definition
Type: Ca++ channel blocker
Mechanism: Dilates main coronary arteries and arterioles in both normal and ischemic areas of the heart, inhibits spasms of the coronary arteries
Dose: 10-20mg TID to control angina
Max 180mg/day |
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