Term
Side effects of Class 1a Anti-arrhythmics |
|
Definition
Refractory Heterogeneity-> Torsades de pointes-> Recurrent lightheadedness-Quinidine Synecopy
Vagolytic
Quinidine- Increases Digitalis levels Procainamide- Transient Lupus Symptoms |
|
|
Term
Side effects of Class 1b Anti-arrhythmics |
|
Definition
CNS Side Effects: Tremor, Nausea, Light-headedness
B-blockers increase lidocaine clearance |
|
|
Term
Side effects of Class 1c Anti-arrhythmics |
|
Definition
|
|
Term
Side effects of Class 2 Anti-arrhythmics |
|
Definition
Hypotension, Bradycardia Increases Clearance of Lidocaine Never with Ca Channel Blockers |
|
|
Term
Side effects of Class 3 Anti-arrhythmics |
|
Definition
Amiodarone- Pulmonary Fibrosis, Hypo/Hyperthyroid, Decreased SA/AV/Inotropy/Tension, Increased Liver enzymes, Tremor/Ataxia/Headaches/Peripheral Neuropathy, Corneal Microdeposits/ Testicular Dysfunction/Skin Discoloration Bretylium- Trans Increase, Perminant Decrease in Catecholamines |
|
|
Term
Side effects of Class 4 Anti-arrhythmics |
|
Definition
Hypotension/Bradycardia, Never with B-blockers |
|
|
Term
Limitations to Adenosine Use |
|
Definition
Short Half-Life
Caffeine/Theophylline Block |
|
|
Term
Indication for Class 1a Anti-Arrhythmics |
|
Definition
Quinidine- All esp A.Fib/A.Flut Procainamide- Ventricular Arrhythmias after MI Disopyramide- Venticular arrhythmias PSVT |
|
|
Term
Indication for Class 1b Anti-Arrhythmics |
|
Definition
Ventricular Arrhythmias,
Digitalis Induced Arrythmias |
|
|
Term
Indication for Class 1c Anti-Arrhythmics |
|
Definition
Paroxysomal Supraventricular Tachycardia Ventricular Tachycardia A.Fib/A.Flut |
|
|
Term
Indication for Class 2 Anti-Arrhythmics |
|
Definition
Stabilize Ventrical in A.Fib/A.Flut Ventricular Re-Entry Arrhythias PAC, PVC, PSVT
Ischemia-Related Ventricular Tachycardia |
|
|
Term
Indication for Class 3 Anti-Arrhythmics |
|
Definition
Amio- A.Fib/A.Flut
Ventricular Tachycardia
Bypass-Tract(Kent) PSVT |
|
|
Term
Indication for Class 4 Anti-Arrhythmics |
|
Definition
Protect Ventrical in A.Fib/A.Flut
Multifocal Atrial Tachycardia
PSVT |
|
|
Term
|
Definition
Paroxisomal Supraventrical Tachycardia |
|
|
Term
Mechanism of Class 1a Anti-arrhythmics |
|
Definition
Decrease Na Conduction Mild Decrease in K conduction |
|
|
Term
Mechanism of Class 1b Anti-arrhythmics |
|
Definition
Decrease Na conduction in Depolarized and Active Heart Tissue, but not Resting Tissue |
|
|
Term
Mechanism of Class 1c Anti-Arrhythmics |
|
Definition
Na: Block Fast Na Conduction
AV: Decrease condution ->
Widen QRS
Prolong AP
Effective on His-Purkinje System |
|
|
Term
Mechanism of Class 2 Anti-arrhythmics |
|
Definition
Decrease AV Node conduction Decrease SA Node Firing Decrease K Conduction |
|
|
Term
Mechanism of Class 3 Anti-arrhythmics |
|
Definition
Amodarone- 1,2,3 Ibutilide- 3 Sotalol- 2,3 |
|
|
Term
Mechanism of Class 4 Anti-Arrhythmics |
|
Definition
Ca Channel Block
Decrease AV/SA Node Conduction |
|
|
Term
|
Definition
Increase K Conduction Decrease Ca Conduction Effective on the AV Node |
|
|
Term
Class 1a Anti-Arrhythmics |
|
Definition
Quinidine, Procainamide, Disopyramide |
|
|
Term
Class 1b Anti-Arrhythmics |
|
Definition
Lidocaine
Tocainide
Mexiletine
Phenytoin |
|
|
Term
Class 1c Anti-Arrhythmics |
|
Definition
Flecainide
Moricizine
Propafenone |
|
|
Term
|
Definition
Sotalol, Propanolol, Acebutylol |
|
|
Term
|
Definition
Amiodarone, Sotalol, Ibutilide, Bretylium |
|
|
Term
|
Definition
|
|
Term
Treatment of Paroxysomal Supraventricular Tachycardia |
|
Definition
Acute: Adenosine, Verapamil, Diltiazem
Chronic: Oral Verapamil, Diltiazem, or Class 2 |
|
|
Term
Treatment of Atrial Fribillation |
|
Definition
Rate: Class 2 or Class 4
Rhythm: Class 1c of 3 |
|
|
Term
Treatment of Ventricular Arrhythmias |
|
Definition
IV Lidocaine, Flecainide, Amiodarone |
|
|
Term
What should you be aware of when using lidocaine with a patient on Beta-blockers |
|
Definition
B-blockers decrease the clearance of lidocaine |
|
|
Term
If a patient is in an arrythmic beat has aslo been taking Digoxin what anti-arrythmic drug is indicated and which anti-arrythmic is contra-indicated? |
|
Definition
Indicated: Class 1b
Contraindicated: Quinidine |
|
|