Shared Flashcard Set

Details

Cardio-Path
Valvular Heart Diseae
28
Pathology
Graduate
10/12/2010

Additional Pathology Flashcards

 


 

Cards

Term
What are the common causes of death is aortic stenosis?
Definition

CHF

Leathal Arrythmia

Term
What are the major causes of Aortic Stenosis
Definition

Senile Degeneration (Most common)

Bicuspid

Rheumatic

Post-Inflamatory Scarring

Congenital

Term
When does senile degeneration occur in a patient with normal Aortic Valve vs a bicuspid aortic valve
Definition

Normal: 8th or 9th decade

Bicuspid: 6th or 7th

Term
Causes of Aortic Insufficiency
Definition

Root Dialation

marfan's

Chronic Rheumatic

Endocarditis

Term
What are the causes of mitral Insufficiency
Definition

Leaflets: Endocarditis, Chronic Rheumatic

Tensor/Papillary: Ischemia, Endocarditis

Ventricular: Dialation

Annulus: Calcification

Term
What sex is mitral Prolapse more common in
Definition
Females
Term
How is the molecular composition of a floppy valve different from a normal one?
Definition
More Mucopolysacchirides and less Type III collagen
Term
What syndrome is mitral prolapse strongly associated with?
Definition
Marfan's Syndrome
Term
What are some complications of mitral calcifications
Definition

Thromboembolism

Infective Endocarditis

Term

Causes of Mitral Valve Stenosis

Definition

Rheumatic

Endocarditis

Calcification

Tumor

Term
Diagnosis of Rhematic Fever
Definition

ASO with 2 Major or 1 Major and 2 Minor

Majors: Erythema Marginatum

Subcutaneous Nodules

Chorea

Carditis

Polyarthritis

Minor: Fever

CRP/ESR

Prolong PR

Arthalgia

Term
What demographics have a higher incidence of Rheumatic fever
Definition

High pop density

Poverty

Poor living conditions

Undernourishment

Term
Pathogensis of Acute rheumatic Fever
Definition

Pancarditis

Peri:Bread and butter

Myo: Ashoff Bodies

Endocarditis: Valve vegitations

Occasional: Mitral Insufficiency, Arrythmias

Term
Where does chronic Rheumatic heart disease typically manifest
Definition
Left Heart valves
Term
Histology of chronic rhematic fever
Definition

Thicken, shortened Chordae

Valve: Commissural fusion, fibrous thickening

Term
What sex does infective endocarditis typically affect?
Definition
Males
Term
Typical organisms in early and late Prostetic valve endocarditis
Definition

Early: epidermidis

Late: streptococci

Term
Most common organism for native valve endocarditis in an IV drug abuser
Definition
S. aureus
Term
Diagnosis of Endocarditis by Duke's Criteria
Definition

3 Major or 2 major, 3 minor or 1 major, 5 minor

Major: New Regurg

Echo Indicating Valve

Typical Blood organism

Minor: Fever

Atypical organism

Immune Lesions

Vascular Lesions

Irregular Echo

Heart lesion, IV Abuser

 

Term
What side of which valves are vegitations likely to be found?
Definition

Atrial Side of AV valves,

Ventricular Side of Semilunar valves

Term
Complications of Infective Endocarditis
Definition

Insufficiency/Stenosis

Cardiac Abcesses

Suppurative Pericarditis

Embolisms

Renal: Glomerulonephritis, Embolism, Abcess

Term
What are some clinical observations helpful in diagnosing Infective Endocarditis
Definition

Roth Spots

Janeway Lesions

Splinter Hemorrhages

Term
What is the physiological cause of Nonbacterial Infective Endocarditis
Definition
Hypercoaguability
Term
What is another autoimmune endocarditis besides Rheumatic fever and what is the mechanism?
Definition

Libman Sacks Endocarditis (SLE Endocarditis)

Antiphospholipid antibodies

Term

What are complications of Prosthetic valves?

Definition

Infective Endocarditis

Obstuction

Hemolysis

Unbalanced Healing

 

Term
What type of prosthetic valve requires anti-coagulation?
Definition
Mechanical
Term
What part of prosthetic valve is the most common site of infective endocarditis growth?
Definition
Prosthesis-Valve Interface
Term
What is the most common complication of prosthetic heart valves?
Definition
Long-term Calcification and Stenosis
Supporting users have an ad free experience!