Term
What are the MI biochemical markers that fell out of practice and why did they fall out of practice? |
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Definition
AST: Not specific
LDH: Not Specific
Myoglobin: Not Specific
LDH Isoenzymes(LD1/LD2): Takes too long
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Term
What Biomarkers are currently use to eval MI and when are they used |
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Definition
CPK: Used to cal CK-MB fraction
CPK-MB: Confirmation in early MI, Reinfarction Assesment
Troponin: Standard to evaluate possible MI |
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Term
What biochemial marker is being used to evaluate the likelihood of ischemic injury in Unstable Angina? |
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Definition
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Term
What MI Markers would be increased by:
Exercise/Trauma/Muscle Disease
Renal Disease
Hemorrhagic Stoke |
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Definition
Exercise: CPK, CPK-MB
Renal: Troponin T
Stroke: CPK-BB |
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Term
What are the common markers used to evaluate CAD risk in Patients? |
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Definition
total Cholesterol
Triglycerides, LDL, HDL, Apo(A1), Apo(B), App(A) |
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Term
Preanalytical problems in measuring lipids |
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Definition
Position: Standing(Higher) vs Sitting(lower)
Venous Stasis: Increases
Biovariation
Dietary Variation
Medications
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Term
When is the Friedwald Equation invalid |
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Definition
Glycerides over 400, Dyslipidproteinemias |
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Term
What are the CAD equivelents? |
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Definition
AAA, PVD, DM, Chronic Kidney, Coratid Artery Disease, >20% on Framingham's |
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Term
Major Risk factors for CAD |
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Definition
Low HDL, Smoking, HPTN, Family History, Age |
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Term
LDL Goals of Treatment For
0-1 Risks
2+ Risks
Equiv |
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Definition
0-1: <160
2+: <130
Equiv: <100 |
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Term
What are some diseases that will increase your lipids |
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Definition
Hypothyroid
DM
Obstructive Liver
Nephrotic Syndrome |
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Term
What are some new markers for CAD Risk factor |
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Definition
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