Term
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Definition
| Use: Adjuvant w/statin b/c high LDL |
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Term
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Definition
| Use: Primary and secondary prevention of CAD, use in combo |
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Term
| Cholesterol Absorption Blockers |
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Definition
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Term
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Definition
| Use: High triglycerides, high LDL, and low HDL-C levels |
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Term
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Definition
| Use: Severe high TGs and low HDLs like in metabolic syndromes (Type II Diabetes) |
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Term
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Definition
Use: under tongue or IV to terminate angina episode OR oral, patch or ointment for prophylaxis (angina)
HF: IV or sublingual for acute decomp, limited w/hydralazine or in acute decomp (because decrease preload) |
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Term
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Definition
Use: orally for chronic prophylaxis of stable, unpredictable in variant
HT: low and high dose works same, younger and middle-age HT's (non-blacks) respond best |
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Term
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Definition
| Use: Chronic prophylaxis of stable or variant angina |
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Term
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Definition
| Use: Alone as oral prophylaxis of chronic stable angina OR combo w/nitrates, b-blocks, or Ca channel blocks |
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Term
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Definition
| Use: oral, use low dose to minimize bleeding potential |
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Term
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Definition
| Use: Oral, slow onset (b/c pro-drug), long duration (4-8 days), combo w/aspirin |
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Term
| GP IIb/IIIa Receptor Inhibitor |
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Definition
| Use: IV, short duration of action (use in surg), oral doesn't work, combo w/aspirin and hep, Unstable angina |
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Term
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Definition
| Use: IV (hep) SC (LMWH - more reliable absorption and plasma 1/2 life) |
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Term
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Definition
| Use: specific and selective, long 1/2 life, 100% bioavailable (sq) = once-daily x-coat w/out needing to monitor clotting time (unlike close monitor in heparin) |
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Term
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Definition
| Use: IV, combo w/aspirin or other x-plates |
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Term
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Definition
| Use: IV w/in 2 hrs of MI symptoms |
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Term
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Definition
| Use: IV till pain relieved or toxic, some need LARGE cumulative doses but can tolerate them |
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Term
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Definition
Use: post aspirin, b-blockers and reperfusion therapy (w/in 24 hrs of event)
HT: less effective in blacks and old, use w/diuretic, use ARBs (BEST SE PROFILE OR ALL HT DRUGS, but costs), excellent in protecting against nephropathy (esp diabetics), CAD and HF |
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Term
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Definition
| Use: takes days for optimal onset, monitor dose via prothrombin time |
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Term
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Definition
Use: No survival, both chronic heart failure (oral) and acute decomp (IV). Most effective diuretic
HT: pts w/renal insufficiency or resistant HT |
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Term
|
Definition
| Use: No survival, only chronic stable heart failure (oral), combo w/loop diuretics, wide use as 1st line monotherapy for hypertension (esp blacks and old), low Na diet |
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Term
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Definition
| Use: No survival. Combo w/loop and/or thiazide diuretics to prevent K loss |
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Term
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Definition
Use: Yes survival in combo w/standard tx for SEVERE chronic HF (independent of diuretic effects of drug)
HT: comb w/thiazide or loop diuretics to prevent hypokalemia, benefit in HF indicate potential use in HT + HF |
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Term
| Renin Angiotensin Inhibitors (HF) |
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Definition
| Use: yes survival, important in current tx of systolic dysfunction, not as efficient as aldosterone inhib, decrease sx and hospitalizations |
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Term
Direct Arterial Vasodilators
Hydalazine |
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Definition
| Use: Yes survival in combo w/isosorbide dinitrate in chronic HF, most vasodilators (unless also neurohormonal inhibs) NO to survival |
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Term
|
Definition
| Use: low therapeutic index (esp in hypokalemia), restrict to severe HF or pts w/A fib, decrease sx and hospital, no survival, ventricular rate control in pts w/heart fail and A fib |
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Term
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Definition
| Use: Restricted to acute decomp, decrease Sx, maintain circulatory stability, no survival |
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Term
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Definition
| Use: Acute decomp HF only, decrease Sx, maintain circulatory stability, no survival |
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Term
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Definition
| Use: restricted to acute decomp HF, decrease Sx, maintain circulatory stability, NO survival |
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Term
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Definition
| Use: wide-spectrum for both supraventricular and ventricular arrhythmias due to re-entry or ectopic automaticity, term A fib or flutter, comb w/stuff to tx serious ventricular arrhythmia |
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Term
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Definition
| Use: Ventricular aryth b/c re-entry or ectopic automaticity, use against digoxin-induced arryth and long Q-T syndrome (mexiletine and phenytoin), good at suppressing aryth caused by ischemia (MI) |
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Term
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Definition
| Use: SERIOUS VENTRICULAR ARRYTHS b/c re-entry, A fib and flutter, AV nodal re-entry tachy |
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Term
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Definition
| Use: Arryth w/surg, anesthesia, exercise, coke or other xs SNS states, ventricular rate control (so vent can slow when atria going nuts) in A fib and flutter, long Q-T syndrome |
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Term
|
Definition
| Use: broad supraventricular and ventricular aryths b/c of re-entry or ectopic automaticity, term A fib/flutter, combo w/devices for tx serious ventricular arryth, DRUG OF CHOICE for ventricular arryth in cardiac resuscitation, good @ tx arryth in pts w/heart fail (cause less arryths than other drugs) |
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Term
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Definition
| Use: AV nodal re-entry tachy, VENTRICULAR RATE CONTROL in A fib/flutter |
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Term
|
Definition
| Use: AV nodal re-entry tachy (can mistake for anxiety attack) |
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Term
|
Definition
| Use: less in blacks, STRONGLY better w/diuretic, additive w/ACEI or ARB but alone has same efficacy as either of the other two alone |
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