Term
| What are the risk factors for Coronary Artery disease |
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Definition
1. High LDL 2. Obestiy 3. Diabetes 4. Smoking 5. HTN |
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Term
| What's the number one cause of CAD |
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Definition
Decrease coronary flow due to: 1. Stenosis 2. Chronic narrowing or MI 3. Acute lesions |
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Term
| Which coronary artery is a occulsion likely to occur |
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Definition
Left Anterior Descending (40-50%) followed by the Right coronary artery |
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Term
| what are the 4 manifestations of Ischemic artery disease |
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Definition
1. Angina 2. Myocardial infarction 3. Sudden cardiac death due to lethal arrythmia 4. Chronic ischemic heart disease |
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Term
| What are the markers for an MI |
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Definition
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Term
| How do you diagnosis an MI w/in 4 hours? |
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Definition
| ECG: ST elevation & T-wave inversion |
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Term
| How would an MI look after 12-24 hr grossly and histologically |
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Definition
Grossly: Dark Mottling Histologically: Contraction band necrosis & neutrophilic infiltrate |
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Term
| Describe an how a heart would look post MI 24-48 Hours |
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Definition
Gross: Mottling w/ yellow-tan infarct center Histology: Neutrophil infiltrate, coagulation necrosis and loss of striations & nuclei |
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Term
| How would a heart look post MI 3-10? |
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Definition
Gross: Hyperemic border w/ celtral yellow-brown softening, maximum yellow & soft by 10 days Histologically: monocytic infiltrate |
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Term
| How would an infarct look 7 weeks after |
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Definition
Gross: Gray-white Histo: Increased collagen deposition w/ decressed cellularity |
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Term
| After an infract when is the time for risk of arrhythmias |
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Definition
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Term
| 5 to 10 days after an infarct what are you at risk for? |
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Definition
| Risk for free wall rupture |
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Term
| When are you at risk for ventricular aneurysm following an infarct? |
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Definition
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Term
| What are the complications of an MI |
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Definition
1. Cardiac arrhythmias: Cause of death before they reach the hospital 2. LV failure & pulmonary edema 3. Cardiogenic shock 4. Rupture of ventricular free wall, interventricular septum or papillary muscle that lead to cardiac tamponade 5. Aneurysm formation: decrease CO, risk of arrythmia 6 Fibrinous pericardits: friction rub 7. Dressler syndrome: autoimmune resulting in fibrinous pericarditis |
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