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Cardio: Arrhthmias
Step 1 Review
67
Biology
Graduate
12/29/2007

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Cards

Term
Conductivity is associated w/ which phase?
Definition
0
Term
Automatcity is the property of cardiac cells that allows them to _______ ______
Definition
spontaneously depolarize
Term
Automaticity occurs in which phase
Definition
4
Term
The AP of Phase 0 is due to which channels opening
Definition
Fast sodium channels
Term
Phase 1 is known as the
Definition
Early Rapid Repolarization
Term
Phase 1 occurs due to inactivation of _______ & the movement of ______ out of the cell
Definition

Fast Na channels

Potassium 

Term
Phase 2 is the ______ of the AP and is due to an inward ______ _____
Definition

Plateu

Calcium current 

Term
At phase 2 _______ & ______ currents are equal
Definition
inward & outward
Term
Phase 3 is
Definition
repolarization
Term
Phase 3 is ______ and is due to a high ____ conductance resulting in a outwards _____ current
Definition

Repolarization

Potassium

Potassium 

Term
Phase 4 is the
Definition
Resting membrane potential
Term
In a ECG the P wave represents
Definition
Atrial depolarization
Term
Which phase in ventricular AP best represents QRS in an ECG
Definition
Phase O due to influx of Na
Term
Which phase in ventricular AP best represents the T wave in a ECG
Definition
Phase 3 due to efflux of Potassium
Term
In a ECG the QRS complex is
Definition
Ventricular depolarization
Term
The PR interval is the time it takes the AP to travel from the ______ to the _______
Definition

1.  Atrium

2.  Ventricles 

Term
the PR interval is increased by the ____ & decreased by the ____
Definition

1.  PSN

2.  SNS 

Term
The ST segment of a ECG corresponds to phase ___ of ventricular AP. 
Definition
Phase 2 due to outward and inward currents being equal
Term
The T wave is ______ repolarization
Definition
Ventricular
Term
Phase 0 of Pacemaker AP is caused by inward __ ______ and is the ______ of the AP
Definition

1.  Calcium current

2.  Upstroke 

Term
Phase 3 of the pacemaker AP is _____ and caused by an outward __ current
Definition

1.  repolarization

2.  Potassium 

Term
Which phases are not present in Pacemaker AP
Definition
1 & 2
Term
In pacemaker AP phase 4 is a slow depolarization and accounts for ____
Definition
automaticity
Term
Phase 4 in SA node AP is a result of inward __ current
Definition
sodium
Term
Normal AV conduction is dependent on __ channels at the AV node and __ channels at this His bundle
Definition

1.  Calcium

2.  Sodium 

Term
Bradycardia is defined as
Definition
< 60 bpm
Term

Bradycardia is due to abnormal function of ion channels reponsible for automaticty.  Name those channels

 

Definition

1.  If (Na+)

2.  Phase 0 calcium spike or slow channel

Term
Bradycardia involves failure of _____ ____ to generate escape rhythms
Definition
Escape foci
Term
Tachycardia is defined as
Definition
> 100 bpm
Term
Name the 3 mechanism of Tachyarrythmias
Definition

1.  Automaticity

2.  Reentry

3.  Triggered activity 

Term
Name the 2 causes of Automaticity trachycardia
Definition

1.  Enchanced normal automaticity at rates faster than usual

2.  Abnormal automaticity due to activity in channels  or cells that normally do not produce automatic depolarizatoin

Term
Name the 3 requirements for reentry
Definition

1.  Unidirectional block

2.  Slow conduction

3.  Retrograde conduction 

Term
Define 1st degree AV block
Definition
1.  Prolong PT interval > 200ms
Term
1st degree AV block implies a conduction delay at the __ ____
Definition
AV node
Term
Name the 2 types of 2nd degree AV block
Definition

1.  Morbitz I (Wenchkebach)

2.  Mobitz II 

Term
Describe how a EGC would look like for Wenchkebach
Definition
PT interval length gradually increases until an absence of QRS and then it repeats
Term
where is conduction impaired in a Mobitz I block
Definition
Impairment is in the AV node
Term
What's the treatment for Wenckebach
Definition
Usually not necessary
Term
Describe how a Mobitz II block would look like on a ECG
Definition
Normal PT internal lenght w/ a QRS being dropped suddenly, such as 2 P waves for every 1 QRS
Term
Where is conduction impaired in a Mobitz II block
Definition
Beyond the AV nodes, like the His bundles or purkinje fibers
Term
What's the treatment for a Mobitz II
Definition
1.  Pacemaker becaues it can turn into a 3rd degree block
Term
The definition of 3rd AV block is
Definition
complete heart block, it's a failure of conduction between the atria and ventricles
Term
How would an ECG of 3rd degree heart block look like
Definition
No relationship between P-P intervals and QRS intervals
Term
What are the causes of 3rd heart block
Definition
MI and drug toxicity like digitalis
Term
3rd degree heart blocks presesnts w/
Definition
syncope and lightheadedness
Term
What's atrial flutter?
Definition

Rapid regular atrail activity at 180-350 bpm

 

Term
An ECG of atrial flutter has a __ _____ appearances
Definition
saw tooth
Term
Atrial flutter is treated by
Definition
Catheter ablation at isthmus
Term
What's the definition of Atrial Fibrillation
Definition
350-600 bpm
Term
Patients Atrial fibrillation are at a high risk for ______ _______
Definition
Thrombus formation
Term
How does atrial fibrillation appear on a ECG
Definition
Complete erratic rhythm w/ no identifable waves
Term
What's the first line for A fib
Definition
anticoagulants (warfarin) to prevent thrombus formation
Term
After administrering anticoagulants to a person w/ A fib what do you do next
Definition
Give beta blockers
Term
Define Premature Ventricular Contraction (PVC)
Definition
Ectopic ventricular focus firing creating large, wide QRS complex
Term
Define Ventricular trachycardia (V-Tach)
Definition
3 or more PVC in a row
Term
On an ECG had does V tach present
Definition
Wide QRS at 100-200 bpm
Term
How long does V-tach last?  Why is immediate intervention required?
Definition

30 s

Can turn into V fib 

Term
What's the first line treatment for V-tach
Definition
Beta blockers
Term
Define Torsades des Pointes
Definition
Polymorphic VT w/ varying amplitudes of QRS complexes that are twisting about the baseline
Term
Tordes de pointe is ___ ______
Definition
self limited
Term
what can cause tordes de pointes
Definition

Anything that prolongs the QT interval

1.  Hypokalemia

2.  Quinidine

3.  Erythromycin w/ antihistamines 

Term
How do you treat Torsades de Pointes
Definition

1.  beta adrenergic

2.  beta blocker 

Term
Define Ventricular fibrillation (V-fib)
Definition
The most life threatening arrhythmia, there's disordered rapid stimulation of the ventricles
Term
V-fib leads to
Definition

1.  severe drop in CO

2.  Death 

Term
How does v-fib present in a ECG
Definition
Chaotic irregular appearance
Term
how do you treat V-fib
Definition
Electrial defibrillation
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