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Cardiac: Hypertension Drugs
Diuretics: Drugs for Hypertension
16
Health Care
Undergraduate 2
01/06/2009

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Cards

Term

DRUG CLASS: Loop Diuretic

 

Furosemide

(Lasix)

 

Action

Definition

Acts primarily on the ascending limb of the loop of Henle but also on the proximal and distal portions of the tubule to prevent sodium and chloride reabsorption.

 

Results in enhanced excretion of sodium, chloride, potassium, hydrogen, calcium, magnesium, ammonium, bicarbonate, and possible phosphate.

 

Term

DRUG CLASS: Loop Diuretic

 

Furosemide

(Lasix)

 

USES

Definition

Treats edema caused by heart failure. Also treats hypertension alone or in combination with other antihypertensive therapy.

Term

DRUG CLASS: Loop Diuretic

 

Furosemide

(Lasix)

 

Implementation

Definition
  • Administer with food or milk to reduce gastric irritation.
  • DO NOT administer after midafternoon to prevent nocturia.
  • Monitor I & O's.
Term

DRUG CLASS: Loop Diuretic

 

Furosemide

(Lasix)

 

Side Effects To Expect

Definition
  • Oral irritation, Dry Mouth
  • Orthostatic Hypotension
Term

DRUG CLASS: Loop Diuretic

 

Furosemide

(Lasix)

 

Side Effects to Report

Definition
  • Electrolyte Imbalance, Dehydration. (electrolytes most commonly altered are potassium, sodium and chloride.)
  • Hypokalemia is most likely to occur.
  • Hyperuricemia
  • Hyperglycemia
  • Hives, pruritus, rash.
Term

DRUG CLASS: Loop Diuretic

 

Furosemide

(Lasix)

 

Nursing Considerations

Definition
  • Obtain baseline vital signs before therapy.
  • Patients with diabetes require baseline blood glucose levels.
  • DO NOT administer after midafternoon to avoid nocturia.
  • Administer with food or milk to reduce gastric irritation.
  • Monitor Intake Out put
  • Monitor for electrolyte imbalance, dehydration
  • Monitor for digitalis toxicity if given with Digoxin.
Term
DRUG CLASS:  Thiazide Diuretics
 
 
ACTION
Definition
Thiazideds act primarily on the distal tubules of the kidney to block the reabsorption of sodium and chloride ions from the tubule.
 
The unreabsorbed sodium and chloride ions are passed into the collecting ducts, taking molecules of water with them, thus resulting in diuresis. 
Term
DRUG CLASS:  Thiazide Diuretics
 
 
USES
Definition
Antihypertensive properties of the thiazides result from a direct vasodilatory action on the peripheral arterioles.
Term
DRUG CLASS:  Thiazide Diuretics
 
 
THERAPEUTIC OUTCOME
Definition
  • Diuresis with reduction of edema and improvement in symptoms related to excessive fluid accumulation
  • Reduction in elevated blood pressure
Term
DRUG CLASS:  Thiazide Diuretics
 
 
IMPLEMENTATION
Definition
  • DO NOT administer after midafternoon to prevent nocturia
  • Administer with food or milk to reduce gastric irritation. 
Term
DRUG CLASS:  Thiazide Diuretics
 
 
Side Effects To Expect
Definition
  • Orthostatic Hypotension
Term
DRUG CLASS:  Thiazide Diuretics
 
 
Side Effects To Report
Definition
  • Gastric Irritation, Nausea, Vomiting,Constipation
  • Electrolyte Imbalance, Dehydration, (Hypokalemia most likely to occur)
  • Hyperuricemia
  • Hyperglycemia
Term
DRUG CLASS:  Thiazide Diuretics
 
 
NURSING CONSIDERATIONS
Definition
  • Obtain baseline data before administation.
  • DO NOT administer after midafternoon.
  • Give with food or milk
  • Monitor I & O's.
  • Monitor electrolyte levels.
  • May induce hyperglycemia. Monitor blood sugar.
  • Monitor for digitalis toxicity if given with digoxin.
Term
DRUG CLASS:  Thiazide Diuretics
 
 
bendroflumethiazide
 
(Naturetin) 
Definition
Action: Blocks reabsorption of sodium and chloride taking water with them resulting in pee.
 
Uses: Antihypertensive from direct vasodilatory action on the peripheral arterioles.
 
Outcome: Reduces elevated BP
 
Side Effects Expect:Orthostatic hypotension
 
Side Effects Report: Gastric irrritation, nausea, vomiting, constipation, Electrolyte imbalance, dehydration, hyperuricemia, hyperglycemia
 
Nursing Consid:
  • Baseline vital signs.
  • DO NOT administer after midafternoon to prevent nocturia
  • Give with food or milk
  • Monitor for digitalis toxicity if given with digoxin

Term
DRUG CLASS:  Thiazide Diuretic
 
 
chlorothiazide
 
(Diuril)
Definition
Action: Blocks reabsorption of sodium and chloride taking water with them resulting in pee.
 
Uses: Antihypertensive from direct vasodilatory action on the peripheral arterioles.
 
Outcome: Reduces elevated BP
 
Side Effects Expect:Orthostatic hypotension
 
Side Effects Report: Gastric irrritation, nausea, vomiting, constipation, Electrolyte imbalance, dehydration, hyperuricemia, hyperglycemia
 
Nursing Consid:
  • Baseline vital signs.
  • DO NOT administer after midafternoon to prevent nocturia
  • Give with food or milk
  • Monitor for digitalis toxicity if given with digoxin.

Term
DRUG CLASS:  Potassium-Sparing Diuretics
 
 
amiloride
 
(Midamor)
Definition
Action: Acts at the distal renal tubule to retain potassium and excrete sodium resulting in diuresis.
 
Uses:  Usually used in combo with other diuretics in patients with hypertension or heart failure to help prevent hypokalemia.
 
Outcome:  Reduces BP
 
Side Effects Expect: Anorexia, nausea, vomiting, flatulence, headache.
 
Side Effects Report: Electrolyte imbalance, dehydration.
 
Nursing Consid:
  • Baseline vital signs.
  • DO NOT administer after midafternoon to prevent nocturia
  • Give with food or milk
  • DO NOT administer with potassium supplements or salt substitutes.
  • Monitor I & O's.
  • NSAID's reduce diuretic effect.

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