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Cardiac Ms Dysfunction & Failure
Exam 2
166
Medical
Graduate
03/10/2012

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Cards

Term
What describes the most common cause of CHF?
Definition
Cardiac Ms Dysfunction
Term
This is due to underlying abnormality of cardiac structure of function
Definition
Cardiac Ms Dysfunction
Term
What Practice Pattern is cardiac ms dysfunction located under?
Definition
6-D: Impaired Aerobic Capacity/Edurance Associated with Cardiovascular Pump Dysfunction or Failure
Term
Increased arterial pressure leads to what?
Definition
L ventricular hypertrophy
Term
This leads to overstretched contractile fibers and a less-efficient pump
Definition
HTN
Term
Name 5 medications that help with HTN
Definition
ACE inhibitors
Calcium Channel Blockers
Diuretics
Beta-Blockers
Term
What is the second most common cause of CHF?
Definition
Coronary Artery Dz (Myocardial Infarction/Ischemia)
Term
This is related to dysfunction of the L or R ventricle or both as a result of injury.
Definition
CAD (Myocardial infarction/ischemia)
Term
Abnormal heart rhythms
Definition
Cardia arrhythmia
Term
Rapid or slow arrhythmias can impair functioning of L and/or right ventricle. What do these two speeds of arrhythmias do to CO?
Definition
Both decrease
Term
Acute or chronic renal insufficiency produces fluid ___
Definition
Overload
Term
What is the primary tx for renal insufficiency?
Definition
To decrease reabsoorption of fluid from kidneys
Term
Would you likely be on diuretics if you had renal insufficiency?
Definition
Yes
Term
Can be ischemic, hypertrophic, or dilated
Definition
Cardiomyopathy
Term
This is where contraction or relaxation of myocardial ms gibers are impaired.
Definition
Cardiomyopathy
Term
What is the primary cause of cardiomyopathy?
Definition
Pathological process in heart ms
Term
What are the secondary causes of cardiomyopathy?
Definition
Result of systemic dz process (autoimmune conditions)
Term
What is another term for a blocked valve?
Definition
Stenotic
Term
Blocked or incompetent (regurgitative) valves cause the heart ms to contract more ____ which makes the heart work harder.
Definition
Forcefully
Term
Associated with myocardial dilation and hypertrophy
Definition
Heart valve abnormalities
Term
Name 4 common surgeries done for heart valve abnormalities.
Definition
Valve replacement
Valvuloplasty
Valvulotomy
Commissurotomy
Term
When talking about stenotic valvues, which 2 are the most problematic?
Definition
Aortic and Pulmonic
Term
Injury to the pericardium of heart may cause inflammation of the pericardial sac which is known as what?
Definition
Pericarditis
Term
What does pericarditis lead to?
Definition
Pericardial effusion
Term
Elevated intracardiac pressures, limited ventricular diastolic filling, reduced SV
Definition
Cardiac tamponade
Term
This is where the heart cannot expand to let blood come in
Definition
Limited ventricular diastolic filling
Term
What are some medical management techniques for pericardial effusion or myocarditis?
Definition
Nonsteroidal anti-inflammatory agents or corticosteroids
Term
This resulting dysfunction is due to elevated pulmonary artery pressures that increase right ventricular work.
Definition
Pulmonary embolism
Term
Name 4 S&S of PE
Definition
SOB
Chest pain
Pale
Diaphoresis
Term
Is pulmonary embolism life threatening?
Definition
Yes and it comes on very quickly
Term
Name 4 medical management techniques for pulmonary embolism
Definition
-Rapidly acting fibrinolytic agent
-Sedative to decrease anxiety and pain
-Oxygen
-Occasionally embolectomy
Term
Defined by mean pulmonary artery pressure
Definition
Pulmonary HTN
Term
Abnormal if >25 mmHg or in pts with COPD if >20 mmHg
Definition
Mean pulmonary artery pressure
Term
Typical in cervical spinal injuries (transection). Causes imbalance in parasympathetic and sympathetic control. Lack cardiovascular adaptations. Neurogenic edema. Cardiac filling pressures must be monitored.
Definition
SCI effects on Cardiac Ms Dysfunction
Term
Age appears to decrease ___ by altering contraction and relaxation of cardiac ms
Definition
CO
Term
With age there is a higher prevalence of __, __, and other pathological processes.
Definition
Heart dz
HTN
Term
The result of altered embyronic development of normal structure or failure of structure to develop.
Definition
Congenital or Acquired Heart Dz
Term
What are the 2 most common congenital or acquired heart dzs?
Definition
-Congenital bicuspid aortic valve
-Leaflet abnormality assoc. with mitral valve
Term
Name 5 age-associated changes in cardiac performance.
Definition
-Increased systolic arterial pressure
-Decreased aortic distensibility
-May develop L ventricular hypertrophy
-Selective decrease in beta-adrenergic receptor
-Increased pericardial and myocardial stiffness and delayed relaxation
Term
When the aorta becomes stiff, what ventricle has to then work harder?
Definition
L
Term
A common clinical manifestation of heart failure is what?
Definition
Pulmonary edema
Term
What is the most common cause of an increase in pulmonary capillary pressure?
Definition
L Ventricle Failure
Term
The function of this is dependent on several factors that create the dysfunction or can be used to treat.
Definition
Cardiac ms
Term
A syndrome with many pathophysiological and compensatory mechanisms
Definition
CHF
Term
R-sided heart failure means that the RV is not working properly and this will cause back up into where?
Definition
Periphery
Term
Left sided heart failure causes a back up into where?
Definition
Lungs
Term
What type of heart failure is most common?
Definition
Left
Term
What is cachexia?
Definition
wasting
Term
Length-tension ratio
The hearts ability to contract and fill
-The relationship between ventricular filling pressure and ventricular contraction ability.
Definition
Frank-Starling Mechanism
Term
Name 7 influences on Stretch
Definition
1. Atrial contribution to ventricular filling
2. Total blood volume in body
3. Body position
4. Intrathoracic pressure
5. Intrapericardial pressure
6. Venous tone
7. Pumping action of skeletal ms
Term
Why/How does body position effect stretch?
Definition
Sitting is harder for return. Supine is better for venous return to heart. The best way to get venous return is to elevate feet. Never do this with CHF pt because their heart can't handle it
Term
What is the formula for CO?
Definition
CO= HR X SV
Term
What is the equation for SV?
Definition
CO/HR = SV
Term
The result of the degree of myocardial stretch and myocardial contractility
Definition
Strok Volume
Term
2 things that are released from arterial and cardiac myocytes in response to increased stretch
Definition
ANP
BNP
Term
Natriuretic Peptides released by cardiac muscle have effects to reduce __ volume are minor. Used to diagnose and manage disease states.
Definition
Fluid
Term
Levels of ___ are increased with heart disease, heart failure, and acute coronary syndrome.
Definition
BNP
Term
What is normal BNP levels?
Definition
<100
Term
For a pt to be discharged, what must their BNP level be under?
Definition
<500
Term
What levels of BNP are indicative of decompensated CHF?
Definition
>700
Term
Issues with the lungs related to the heart
Definition
Cardiogenic
Term
What does non-cardiogenic mean?
Definition
Issues in the lungs themselves (no heart involvement)
Term
Name the 3 distinct stages of pulmonary function.
Definition
1. Hard to detect; subtle
2. Accumulation of fluid in lungs (pulmonary congestion)
3. Edema; fluid in alveoli; big problems with gas exchange (frothy sputum)
Term
What does ionotropic mean?
Definition
Contractility of the heart
Term
What does chronotropic mean?
Definition
Heart Rate
Term
What is the term used for too much CO2?
Definition
Hypercapnia
Term
Are neural effects rapid or slow?
What about hormonal effects?
Definition
Neural - rapid
Hormonal - slow
Term
Are beta blockers negative or positive chronotropes?
Definition
Negative because they decrease HR
Term
The most influential receptor agonists are sympathetic neurotransmitters __ and __
Definition
Norepi
Epi
Term
Alpha-adrenergic receptors have a __ effect on the heart.
Definition
Ionotropic
Term
Beta-adrenergic receptors have a ___ effect on the heart.
Definition
Chronotropic
Term
Parasympathetic via vagus nerve and neurotransmitter acetylcholine are __
Definition
Inhibitory
Term
Name 2 alpha-adrenergic receptors?
Definition
Alpha 1 and 2
Term
Marginally increases ionotropic effect
Definition
Alpha 1
Term
Activates inhibitory G protein, which decreases ionotropic effect
Definition
Alpha 2
Term
Name 2 beta-adrenergic receptors
Definition
Beta 1 and 2
Term
__ Stimulation promotes vasodilation of capillary bed and ms relaxation of bronchial tracts
Definition
Beta 2
Term
___Stimulation increases HR and myocardial force of contraction
Definition
Beta 1
Term
__ proteins transmit stimulatory (Gs) or inhibitory (G1) signals to catalytic unit
Definition
G
Term
Activation of __ __ leads to an increase in myocardial force of contraction
Definition
Adenylate cyclase
Term
Sympathetic neural function of heart is profoundly affected in __
Definition
CHF
Term
Falling ___ complex function in CHF is related to insensitivity of falling heart to beta-adrenergic stimulation
Definition
RGC
Term
Can result in cirrhosis if long term
Definition
Hepatomegaly
Term
Increased fluid volume leads to __ __ __, preventing adequate perfusion of O2.
Definition
Hepatic venous congestion
Term
Body stimulated erythropoeitin to get more RBC b/c the heart needed more oxygen
Definition
Polycythemia
Term
severe, long standing HF can be caused by this
Definition
Anemia
Term
Thrombocytopenia - low platelets
Definition
Hemostasis
Term
CHF without cardiomyopathy tends to have a __ in average diameter of type 1 and 2
Definition
Decrease
Term
CHF with cardiomyopathy tends to have Type 1 and 1 muscle fiber __
Definition
atrophy
Term
Isometric maximal ms strenth of persons with CHF is reduced by __ %
Definition
50%
Term
Sympathetic neural function can reduce blood flow to the pancreas and impair __ secretion and __ tolerance.
Definition
Insulin
Glucose
Term
What is the importance of sympathetic neural function on the pancreas?
Definition
Importance is related to hypoxic and dysfunctional heart ms and depends on glucose metabolism
Term
Sympathetic neural function causes a an increase in __ by the pancreas which increases the synthesis of triglycerides.
Definition
Acetyl-CoA
Term
Name 5 nutritional and biochemical aspects
Definition
1. Stomach and intestinal abnormalities occur
2. Anorexia and malnutrition
3. Protein-calorie deficiency
4. Persons with CHF may demonstrate a decreased production of erythropoeitin, decreased synthesis of 1,25-dihydroxycholecalciferol, and impaired intermediary metabolism
5. Persons with CHF may benefit from enteral and parenteral products
Term
Persons with CHF may demonstrate what 3 things?
Definition
1. Decreased production of erythropoietin
2. Decreased synthesis of 1,25-dihydroxycholecalciferol
3. Impaired intermediary metabolism
Term
Breathlessness or air hunger
Definition
Dyspnea
Term
Unexplained episodes of shortness of breath occur in the supine position
Definition
Paroxysmal Nocturnal Dyspnea
Term
The development of dyspnea in recumbent position
Definition
Orthopnea
Term
Name 3 symptoms of abnormalities in sympathetic neural function
Definition
Orthopnea
Dyspnea
Paroxysmal Nocturnal Dyspnea
Term
Name 10 S&S of CHF
Definition
1. Breathing patterns
2. Rales (Crackles)
3. Heart Sounds
4. Peripheral Edema
5. Jugular Venous Distension
6. Pulsus alternans
7. Changes in extremeties
8. Weight gain
9. Sinus tachycardia
10. Decreased exercise tolerance
Term
What might breathing patterns look like in a pt with CHF?
Definition
Rapid respiratory rate at rest with quick and shallow breaths (short shallow breaths are not engaging the diaphragm)
Term
Abnormal breath sounds that occur during inspiration reflecting fluid in alveoli
Definition
Rales (crackles)
Term
What actually makes the crackles sound?
Definition
Alveoli popping open
Term
__ heart sound indicates a noncompliant left ventricle and is associated with CHF
Definition
S3
Term
Retention of fluid/pitting edema
Definition
Peripheral edema
Term
Jugular venous distention results from what?
Definition
Fluid overload
Term
A mechanical alteration of femoral or radial pulse. Characterized by a regular rhythm and alternating strong or decreased pulse.
Definition
Pulsus Alternans
Term
How might the extremeties change with CHF?
Definition
May become cold and appear pale and cyanotic. Indicative of hypoxia or venous insufficiency
Term
Why might a person with CHF have weight gain?
Definition
As total body fluid volume increases, so does body weight
Term
Why will a person with CHF have decreased exercise tolerance?
Definition
Decreased CO
Term
Name 4 S&S of Pulmonary Congestion
Definition
1. Dyspnea, dry cough - hard to bring air in b/c of fluid in lungs
2. Orthopnea
3. Paroxysmal nocturnal dyspnea
4. Crackles and wheezing
Term
Name 7 S&S of Acute Pulmonary Edema
Definition
1. Marked dyspnea
2. Pallor or cyanosis
3. Diaphoresis
4. Tachycardia
5. Anxiety
6. Agitation
7. Pink/frothy sputum
Term
Name 6 S&S of low CO
Definition
1. Hypotension (because of low CO and BV)
2. Tachycardia
3. Lightheadedness, dizziness (not getting enough O2 to brain)
4. Fatigue (not getting good O2 to tissues)
5. Weakness
6. Poor exercise tolerance
Term
What are the 2 adventitious heart sounds?
Definition
S2, S3
Term
Name 4 clinical manifestations associated with CHF.
Definition
Low CO
Adventitious heart sounds
Enlarged heart
Possible functional mitral and tricuspid regurgitation
Term
Why might a person with CHF have an enlarged heart?
Definition
Because of the volume overload overtime stretches out the heart
Term
What is the most common cause of R ventricle heart failure
Definition
LV failure
Term
Nae 2 things that right ventricular failure can result from
Definition
Mitral valve disease
Acute or chronic lung disease
Term
Name 7 Clinical Manifestations of RV failure.
Definition
1. Dependent edema
2. Jugular Venous Distension
3. Weight gain (3 lbs in 1 day is a lot)
4. Hepatomegaly
5. Ascites (truncal edema - makes it hard to breath)
6. Cyanosis
7. Anorexia, nausea, bloating
Term
Elevated pressures caused by LV failure end up causing RV failure as well.
Definition
Biventricular failure
Term
Various compensatory mechanisms and therapeutic intervention allow the heart to return to a functional, albeit reduced, CO. This scenario is defined as what?
Definition
Compensated heart failure
Term
Exercise tolerance is usually markedly limited with what?
Definition
Compensated heart failure
Term
Used to evaluate effects of pharmacological agents and exercise training in CHF. Looks at how the pt thinks they are responding to the medication.
Definition
Minnesota Living with Heart Failure Questionnaire
Term
Depression is associated with __ risk of functional decline in pts with congestive heart failure.
Definition
Increased
Term
What are some radiological findings in CHF?
Definition
Evaluation of size and shape of cardiac silhouette (L VEDV) and the presence of interstitial, perivascular, alveolar edema (fluid in lungs)
Term
What lab findings will be noted in CHF?
Definition
Proteinuria
Elevated uring specific gravity
Elevated BUN
Elevated Creatine levels
Decreased erythrocyte sedimentation rate
Elevated liver enzymes
Term
What will an echocardiography look at in pts with CHF?
Definition
Left Ventricular EF
Structure of LV
Other structual abnormalities
Term
Name 5 treatments for heart failure.
Definition
-Depends if its chronic or acute
-Correction of underlying cause is possible
-Aggressive management of HTN and CAD
-Pharmacologic therapies
-Sx intervention
Term
There are several medications used to treat CHF, what are they trying to fix?
Definition
-Directed at underlying cause(s)
-Improve heart pump
-Reduce workload
-Control sodium intake and water retention
Term
If you are taking too many fat-soluble vitamins your body can't get rid of them as easily as what type of vitamins?
Definition
H20 Soluble
Term
What dietary changes and nutritional supplementation should a person with CHF do?
Definition
-Supplement vitamins, minerals, and amino acids
-Decreased sodium intake
-Fluid restrictions
-Eating heart healthy foods with low cholesterol/fat
Term
What all types of pharmacological treatments would a person with CHF need?
Definition
1. Diuretics
2. Aldosterone agents
3. Digoxin and other positive ionotropic agents
4. Dopamine
5. Dobutamine
6. Amrinone/Milrinone
7. Vasodilators/Venodilators
8. Angiotensin-converting enzyme inhibitors and alpha receptor blockers
9. Beta-adrenergic antagonists and partial agonists
10. Anticoagulation (INR, PT, PTT)
Term
What 3 types of medications can exacerbate heart failure
Definition
Antiarrhythmic agents
Calcium channel blockers
NSAIDs
Term
When is ICD (implantable cardioverter defibrillator) recommended?
Definition
When EF is less than or equal to 35% and mild to mod symptoms
Term
Electrical stimulation of R and L ventricles in synchronized manner provided by biventricular pacemaker device. Improves cardiac function and hemodynamics.
Definition
Cardiac Resynchronization Therapy
Term
Name 3 types of mechanical treatment that can be done on CHF pts?
Definition
1. Dialysis and ultrafiltration
2. Assisted circulation
3. Ventricular assist device
Term
These remove fluid from pleural and abdominal cavities
Definition
Dialysis and ultrafiltration
Term
An intraaortic balloon counterpulsation using a pump (IABP)
Definition
Assisted circulation
Term
This device provides force to eject blood (helps heart to contract)
Definition
Ventricular Assist Device
Term
Name 3 surgical treatments for pts with CHF
Definition
-LV muscle flap - cardiomyoplasty; assists with LV contraction
-Cardiomyoplasty (partial left ventriculectomy) - ms flap that helps ventricles contract
-Cardiac transplantation
Term
Name methods of cardiac transplantation
Definition
-Xenograft - non-human primate
-Allograft - human
-Orthotopic - take a heart out and put another in
-Heterotopic - use of 2 hearts
Term
Name 11 significant predictors of survival and prognosis for CHF pts.
Definition
1. Decreased LVEF
2. Worsening NYHA functional status
3. Degree of hyponatremia
4. Decreasing peak exercise oxygen uptake
5. Decreasing hematocrit
6. Widening QRS on 12-lead ECG
7. Chronic hypotension
8. Resting tachycardia
9. Renal insufficiency
10. Intolerance to therapy
11. Refractory volume overload
Term
What are the benefits of exercise training with CHF pts?
Definition
Improvement in symptoms, clinical status, and exercise duration.
Term
In pts with CHF, qualify of life is related to what?
Definition
The ability to exercise.
Term
Exercise training during continuous intravenous __ fusion. This helps to improve heart contractility. There are no adverse effects and no clinically significant differences.
Definition
Dobutamine
Term
How does ventricular assist devices help with exercise training?
Definition
Improved technology has enabled pts to exercise
Term
What 2 ventilation techniques can improve exercise performance
Definition
CPAP and BiPAP
Term
What is the difference between CPAP and BiPAP?
Definition
CPAP is continuous and BiPAP alternates air pressure
Term
What are some types of ventilatory muscle training that help faciliate diaphragmatic breathing.
Definition
Breathing exercises
Expiratory ms training
Inspiratory ms training
Term
What is the goal of exercise training in pts with CHF
Definition
To decrease workload on heart without the loss of function
Term
Name 8 self-management techniques for muscle training.
Definition
1. Assisting pt with taking responsibility for their own health
2. Individualized and family education and counseling
3. Optimization of medical therapy
4. Vigilant follow-up
5. Increased access to health care professionals
6. Early attention to fluid overload
7. Coordination with other agencies
8. Physician directed care
Term
In pts with CHF, the PT should assess for S&S of __ at each visit.
Definition
Decompensation
Term
What is chronotropic?
Definition
Heart rate
Term
Name 4 S&S of L HF
Definition
SOB
Irritable
Aggitation
Increased respiratory effort
Term
Name 4 S&S of exercise intolerance
Definition
Fatigue easily
SOB
Dizziness
Diaphoresis
Term
What are 2 things to watch that might suggest pt has decompensation
Definition
Increased HR and low BP at rest
Chronotropic incompetence
Term
PT must know to terminate exercise early if any of the following are observed (5)
Definition
1. Acute decrease in BP
2. Onset of angina
3. Significant dyspnea or fatigue
4. Feeling of exhaustion
5. Serious exercise-induced arrhythmias
Term
Name 4 treatment modifications that are frequently indicated in CHF pts.
Definition
1. Low level initially and progress slowly
2. Frequent 1-2 min. rests interspersed with activity will reduce cost of more demanding activities
3. Caution positioning pt in supine or prone due to complaints of orthopnea
4. Avoid breath holding and Valsalva maneuver because of decreased CO
Term
Acute CHF can occur due to __ or __ drug levels
Definition
Inadequate or toxic
Term
Many drugs used to treat CHF are associated with what 3 things?
Definition
1. Orthostatic and postexercise hypotension
2. Caution against quick changes to upright positions
3. Exercise cooldown imperative so blood doesn't pool in legs
Term
What is the ultimate exercise-related goal in CHF pts.
Definition
Exercise duration of 30 min of continuous exercise
Term
How should exercise be progressed in pts with HF?
Definition
-Low level, gradually progressive aerobic exercise improves exercise capability (starting intensity often based on symptomatology)
2. Interval training with brief rest periods as needed allows to accumulate greater volume of exercise
3. Warm-up and cooldown are VERY important
Term
Low to moderate intensity resistance training is often beneficial for patients with what type of HF?
Definition
Stable
Term
Is inspiratory ms training advantageous for pts with HF?
Definition
Yes
Term
Pt education includes what 4 things?
Definition
-Weight 1st thing in the morning
-Take action if 3lbs or more is gained
-Symptoms of decompensation and exercise intolerance
-Side effects of meds and symptoms of toxicity
Term
What precaution should you take when working with a pt on telemetry?
Definition
YOu can leave the room but be sure to stay within range!
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