Term
What are the metabolically important linear polysaccharides? |
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Definition
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Term
The free C4 end of a polysaccharides is what? |
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Definition
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Term
The Free C1 end of a polysaccharides is what? |
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Definition
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Term
Cellulose has what kind of carbon bonding? |
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Definition
Beta 1-4 glycoside bonding |
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Term
Amylose has what kind of carbon bonding? |
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Definition
Alpha 1-4 glycoside bonding |
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Term
Amylopectin has what kind of carbon bonding? |
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Definition
Alpha 1-4 and Alpha 1-6 glycoside bonding |
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Term
The formation of an alpha 1-6 bond is indicative of what in a polysaccharide? |
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Definition
branching. The area of the alpha 1-6 bond is coined the branching point |
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Term
How many reducing and non-reducing ends does a linear polysaccharide have? |
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Definition
One reducing and one non-reducing end |
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Term
How many reducing and non-reducing ends do branched polysaccharides have? |
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Definition
1 reducing end and a variable amount of non-reducing ends |
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Term
What is the structural difference between amylopectin and glycogen? |
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Definition
While both are branched polysaccharides the glycogen has many more branch points and non-reducing ends |
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Term
What is the significance of a higher number of non-reducing ends in a branched polysaccharide? |
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Definition
The more branched a branched polysaccharide the faster it is metabolized |
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Term
Dietary starch is composed of what polysaccharides? |
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Definition
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Term
Dietary fiber is composed of what polysaccharides? |
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Definition
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Term
What enzymes work in the digestion of amylose? |
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Definition
alpha-amylase and maltase |
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Term
What enzymes work in the digestion of amylopectin? |
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Definition
alpha amylase, maltase, and alpha dextrinase |
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Term
Where does alpha amylase function? |
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Definition
active alpha amylase will digest polysaccharides in the mouth (within saliva) and in the duodenum of the small intestine (within pancreatic juices) |
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Term
How does active alpha-amylase get to the duodenum of the small intestine? |
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Definition
alpha-amylase is secreted by the pancrease along with other digestive enzymes and bicarb |
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Term
What bonds do alpha-amylase cleave? |
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Definition
alpha 1-4 glycoside bonds but will not cleave terminal alpha 1-4 glycoside bonds |
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Term
what bonds does maltase cleave? |
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Definition
alpha 1-4 glycoside bonds |
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Term
What is the product of Amylopectin cleaved by alpha amylase? |
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Definition
Maltose, maltriose, and alpha-dextrins |
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Term
What is the product of amylose cleaved by alpha-amylase? |
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Definition
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Term
What is the rate-limiting step in the digestion of polysaccharides? |
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Definition
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Term
What does maltase act on? |
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Definition
maltose (disaccharide) and maltotriose (trisaccharide) |
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Term
what does alpha-dextrinase act on? |
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Definition
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Term
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Definition
alpha-dextrins are the branch chain products of the degradation of amylopectin by alpha-amylase |
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Term
what bonds does alpha-dextrinase cleave? |
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Definition
alpha 1-4 bonds and alpha 1-6 glycoside bonds |
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Term
What enzymes of polysaccharide digestion are endoglycosidases? |
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Definition
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Term
What enzymes of polysaccharide digestion are exoglycosidases? |
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Definition
alpha-dextrinase and maltase |
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Term
What are abnormally high levels of alpha-amylase in the blood indicative of? |
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Definition
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Term
Where in the body is maltase and alpha-dextrinase found? |
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Definition
Brush border: epithelial cells of the intestine |
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Term
What is the chemical mechanism by which the alpha 1-4 and alpha 1-6 bonds are cleaved? |
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Definition
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Term
What defines active transportation? |
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Definition
Transportation of substances against a concentration gradient |
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Term
What transporter is responsible for insulin-stimulated uptake of glucose? |
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Definition
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Term
What transporter is responsible for the transport of fructose? |
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Definition
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Term
What tissue responds to insulin for glucose uptake? |
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Definition
Skeletal and cardiac muscle, adipose tissue |
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Term
What transporter is involved in the basal uptake of glucose and has a low Km value? |
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Definition
Glut1 and Glut 3. The low Km drives the preferential uptake of glucose to these cells |
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Term
What glucose transporter targets the liver, pancreatic beta cells, the kidney, and the small intestine? |
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Definition
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Term
Glut 2 has a high Km value which means that it will absorb glucose when? |
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Definition
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Term
What is the SGLT1? What is it's function? |
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Definition
Sodium linked transporter of glucose. It participates in active transport of glucose in the small intestine and kidneys |
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Term
What type of glucose transporters does liver have? |
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Definition
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Term
What is the effect of decreased insulin on glucose transporters? |
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Definition
decreased the number of active Glut-4 transporters |
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Term
What sort of glucose transporters are found in the Kidneys? |
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Definition
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Term
What sort of Glucose transporters are found in the Small Intestine? |
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Definition
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