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Cancer Pain
Overview
22
Astronomy
6th Grade
10/18/2013

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Cards

Term
directly related to the presence of primary or metastatic disease
Definition
2/3 of patients with cancer pain
Term
develop pain syndromes due to cancer treatment or other related causes
Definition
1/3 of patients with surgery, radiation, chemotherapy, etc
Term
rapid titration
Definition
severe pain
Term
slower titration
Definition
moderate pain
Term
very slow titration
Definition
mild pain
Term
treatment for mild cancer pain for patients not on analgesics
Definition
begin with acetaminophen or NSAIDs (non-opioid medications)
Term
generally avoided in mild cancer pain due to irreversible anti-platelet effects
Definition
aspirin
Term
treatment for mild cancer paint for aitnets on analgesics
Definition
consider titrating short-acting opioid and beginning bowel regiment
Term
limits use during myelosuppressive chemotherapy
Definition
antipyretic action of tylenol
Term
treatment of moderate cancer pain
Definition
codeine, hydrocodone, tramadol;
Term
treatment of severe cancer pain
Definition
morphine, hydromorphone, oxycodone, fentanyl, methadone
Term
Multiple dosage forms and administration routes : PO, IV, SQ< SL, IM, R, Epidural
Definition
Morphine
Term
about 1.5 mg per 10 mg of morphine
Definition
Hydromorphone
Term
active metabolite of oxycodone; twice as strong
Definition
Oxymorphone
Term
more potent than morphine; no parenteral formulation available
Definition
Oxycodone
Term
pharmacokinetics do not match pharmacodynamics
Definition
methadone
Term
0.1 mg = 10 mg morphine (intravenous)
Definition
Fentanyl
Term
non-competitive NMDA receptor antagonists; low doses provide analgesia, modulate hyperalgesia opioid tolerance
Definition
IV Ketamine
Term
postoperative pain; cryosurgery-associated pain and cramping; chemotherapy toxicity; chemotherapy infusion; immunotherapy infusion; vascular events, etc
Definition
Acute Pain Syndromes
Term
Bone pain, muscle pain, headache and facial pain; paraneoplastic syndromes
Definition
Tumor-related Pain Syndromes
Term
postchemotherapy syndromes; chronic post-surgery pain syndrome; chronic post-radiation pain syndromes
Definition
associated with treament
Term
Opioid Toxicity Syndrome
Definition
Neurotoxicity
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