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Cancer/Oncology
Herzing Orlando exam
100
Nursing
Undergraduate 2
02/05/2012

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Term
Cancer
Definition
mutation of normal cells
Term
neoplasm
Definition
abnormal growth of of tumor
Term
benign neoplasm
Definition
slow growing localized non malignant growth with well defined borders; easily moved; only cause damage by compressing tissues
Term
malignant neoplasm
Definition
aggressive growths that invade and destroy surrounding tissue
Term
metastasis
Definition
occurs when malignant cells travel through blood or lymph system and invade other tissues and organs to form a secondary tumor
Term
malignant cells
Definition
rapid cell division; metastasize, aleration in cell structure, self survival
Term
Cancer risk factors
Definition
#1 age over 65; gender; geographic location; 15% genetics; immune disturbance; chemical agents; race; tobacco; ETOH; diet;
Term
CAUTION
Definition
change in bowel or bladder habits; a sore that doesnt heal; unusual bleeding or discharge; thickening or lump in breast; indigestion or difficulty in swallowing; obvious change in wart or mole; nagging cough or hoarseness
Term
Safety regarding patient receiving bracytherapy
Definition
private room, posting about radiation safety precautions,dosimeter badges, pregnant staff members are not assigned, no children or pregnant visitors, limiting to 30 minutes daily, visitors maintain a 6-foot distance from the radiation source.
Term
Time distance shield
Definition
protection from radiation
Term
chemotherapy is used
Definition
to treat systemic disease rather than localized lesions that can be done with surgery or radiation.
Term
neoadjuvant
Definition
reducing tumor size preoperatively
Term
adjuvant
Definition
destroying tumor cells postoperatively
Term
Chemotherapy goals
Definition
cure, control, palliation,
Term
extravasation
Definition
nadver-tently leak from a vein
Term
vessicants
Definition
gents that, if deposited into thesubcutaneous tissue (extravasation), cause tissue necrosis anddamage to underlying tendons, nerves, and blood vessels.
Term
vesicant drugs
Definition
isplatin (Platinol-AQ), dactinomycin(Cosmegen), daunorubicin (DaunoXome), doxorubicin, ni-trogen mustard (Mustargen), mitomycin (Mutamycin), pacli-taxel (Taxol), vinblastine (Velban), vincristine (Oncovin),vindesine (Eldisine), and vinorelbine (Navelbine)
Term
Signs of extravasation during vesicant administration
Definition
Absence of blood return from the intravenous (IV)catheter,Resistance to flow of IV fluid,Burning or pain, swelling or redness at the sit
Term
Alkalating agents side effects
Definition
bone marrow suppression, cystitis, stomatitis, alopecia, renal toxicity, gonadal suppression
Term
Nitrosureas (BCNU, CCNU)
Definition
cross the blood brain border
Term
nitrosureas side effects
Definition
thrombocytopenia, delayed and cumulative myelosuppresion
Term
myelosuppression
Definition
suppression of the bone marrow, results in decrease of wbc;
Term
anthracyclines cause irreversible cumulative cardiac toxicity
Definition
when total dosage reaches600 mg/m
and 550 mg/m
Term
Detection of Breast cancer begins at age
Definition
20
Term
women age 20-39 get breast exams every
Definition
3 years
Term
women age 40+ get mammograms
Definition
yearly
Term
detection of colon cancer
Definition
ages 50+ should have a yearly occult blood test
Term
digital rectal exam and flexible sigmoidoscopy should be done
Definition
every5 years
Term
colonoscopy with barium should be done
Definition
every 10 years
Term
Pap smears should be done
Definition
yearly
Term
detection of prostate cancer: digital rectal and prostate specific antigen (PSA)
Definition
yearly starting at age 50
Term
Grading
Definition
classifies tumor based on degree of abnormal cells under miscroscope
Term
1 is least abnormal to 4 being most abnormal
Definition
grading
Term
staging
Definition
Tumor size, N indicates lymph involvement, M indicates distance of metastasis
Term
T0, Tis, T1, T2, T3, T4,
Definition
No evidence of tumor, insitu, progressive degree of size
Term
N0; N1a-N2a;
Definition
no abnormal lymph node detected; regional nodes with increasing degree NO METASTATIS
Term
n2A-n2B
Definition
progressive regional lymph nodes involvement; metastasis suspected
Term
M0
Definition
no distant metastasis
Term
M1,2,3
Definition
increasing degree of metastasis
Term
radiation therapy uses
Definition
reduce tumor size, kill tumor, relieve obstruction, or decrease pain
Term
brachytherapy (internal radiation)
Definition
implanted to body; ingested as a solution; ingested as a solution to bloodstream of body cavity; introduced with a catheter;
Term
brachytherapy side effects
Definition
fatigue, anorexia, immunosuppression
Term
external radiation therapy (tattooing)
Definition
tx is 5-15 mins a day/5 days a week/for 2-7 weeks. NO RISK FOR RADIATION ON OTHERS.
Term
side effects of external radiaton therapy (teletherapy)
Definition
tissue damage (erythema, sloughing, hemorrhage; ulceration of oral mucosa; N/N; radiation pneumonia; fatigue; alopecia; immunosuppression
Term
client teaching for external radiation therapy (teletherapy)
Definition
wash marked area with plain water and pat dry; no soaps or chemicals on area; avoid rubbing/scratching/scrubbing; loose fit clothes; protect skin from sun during tx and 1 year post tx with SPF15; proper diet and rest; cover head with hat if alopecia is present
Term
dysplasia
Definition
alteration in the size, shape, and organization of differentiated cells
Term
anaplasia
Definition
presence of completely undifferentiated tumor cells that don’t resemble cells of the tissues of their origin
Term
hyperplasia
Definition
increase in the number of normal cells in a normal arrangement in a tissue or an organ
Term
diagnosis of breast cancer
Definition
fine needle aspiration, biposy
Term
drug administered with methotrexate to protect cells
Definition
Leucovorin is administered with methotrexate to protect normal cells, which methotrexate could destroy if given alone
Term
Medication to avoid giving with methotrexate that causes renal toxicity
Definition
Probenecid should be avoided in clients receiving methotrexate because it reduces renal elimination of methotrexate
Term
A good indicator of colon cancer
Definition
colectoral polyps
Term
If a is experiencing thrombocytopenia what should be assessed
Definition
signs of bleeding, such as petechiae, purpura, epistaxis, and bleeding gums
Term
Where do antimetabolites work in the cell hases
Definition
Antimetabolites act during the S phase of the cell cycle, contributing to cell destruction or preventing cell replication.
Term
what does ABCD stand for when assessing skin lesions
Definition
A stands for "asymmetry," the B for "border irregularity," the C for "color variation," and the D for "diameter."
Term
how to reduce risk of stomatis pain
Definition
To decrease the pain of stomatitis, the nurse should provide a solution of hydrogen peroxide and water for the client to use as a mouth rinse
Term
how long after chemo does stomatitis appear
Definition
occurs 7 to 10 days after chemotherapy begins
Term
what severe adverse effect does tamoxifen cause
Definition
visiual acuity changes
Term
the 5 most popular places for cancer metastasis
Definition
liver, lymph nodes, lung, bone, and brain
Term
Monthly breast self-examinations should be done
Definition
between days 7 and 10 of the menstrual cycle
Term
how long after use of floxuridine administration does bone marrow suppression become noticeable
Definition
Bone marrow suppression becomes noticeable 7 to 14 days after floxuridine administration
Term
normal platelet count
Definition
In an adult, a normal count is about 150,000 to 450,000 platelets per microliter of blood
Term
Platelet counts below 20,000 mean
Definition
spontaneous bleeding may occur and is considered a life-threatening risk.
Term
single most significant risk factor of getting cancer
Definition
age
Term
warning sign of lung cancer
Definition
blood streaked sputum
Term
S/S of extravasation
Definition
pain, redness, swelling, inability to get blood return, change in quality of infusion
Term
Bulsulfan side effect:
Definition
abrupt onset of bulsulfan induced ancytopenia which is a decrease in all blood cell components.
Term
client teaching for thrombocytopenia
Definition
avoid straight razors, monitor stools for bleeding, avoid contact sports, apply ice to an area after trauma, avoid dental work, avoid aspirin, use only ETOH based mouthwashes, avoid IM injections
Term
most normal response to chemotherapy
Definition
fatigue
Term
neutropenic precaution with fever over 101 degrees
Definition
notify physician
Term
3 step ladder for pain
Definition
nonnarcotic (tylenol), weak narcotic (codeine), strong narcotic(morphine)
Term
Most common cause of lung cancer
Definition
inhaled carcinogens
Term
Non small cell lung cancer includes
Definition
squamous cell, large cell, adenomacarcinoma cell and bronchoalveolar cell. All carcinomas
Term
Most frequent sign of lung cancer is
Definition
change in a chronic cough
Term
Early signs of lung cancer
Definition
dyspnea, chest or shoulder pain, recurring fever, hemoptysis, dysphagia, pericadial effusion
Term
Tool to aspirate cells from esophogeal ultrasound
Definition
fine needle aspiration
Term
Radiation may offer cure by controlling neoplasms that can't be surgically detected while irradiation
Definition
may reduce the size of the tumor
Term
Signs of breast cancer include
Definition
nipple discharge, nipple retraction, lymphadenopathy
Term
How should the arm of a patient with a recent modified radical mastectomy be positioned and why
Definition
eleveated as much as possible to prevent lymphedema; elevation supports lymph drainage.
Term
Fibroadenomas:
Definition
firm round moveable benign tumors; non tender; removed at times for dx
Term
Monthly self breast exams should be performed
Definition
within 7 to 10 days of the menstrual cycle
Term
What kind of exam is recommended for wome age 20 to 40
Definition
a professional breast exam
Term
Oncological emergencies
Definition
Spinal cord compression, Superior Vena Cava syndrome, DIC, Cardiac tamponade
Term
Early signs of spinal cord compression
Definition
back pain, cold, numbness, tingling, paresthesia; nurse monirots vitals and neuro check
Term
Easrly signs of Superior Vena cava syndrome
Definition
periorbital edema, facial edema, jugular vein distention LATE edema of neck/arms/hands, dysphagia, SOB
Term
Signs of DIC
Definition
decreased blood flow to major organs, tachycardia,oliguria, dyspnea, abnormal bleeding
Term
S/S of prostate cancer
Definition
frequency, decrease in stream, dysuria, hematuria, abnormal prostate
Term
Post prostate surgery care
Definition
monitor for frank bleeding;urge to void is normal; continuous bladder irrigation; irrigation solution may be absorbed so monitor for hyponatremia aka TURP syndrome
Term
A radical mestectomy includes
Definition
removal of entire breast, underlying chest muscles, and lymph nodes
Term
modifies radical mastectomy includes
Definition
removal of breast tissue and lymph nodes under the arm
Term
simple mastectomy includes
Definition
removal of complete breast only
Term
lumpectomy includes
Definition
removal of tumor and surrounding tissues
Term
Three way catheters cause bladder spasms because
Definition
of the wide diameter of the catheter and pressure of the retention balloon
Term
alkylating agent Cytoxan is cell cycle
Definition
NON-SPECIFIC
Term
Fluoracil aka 5-FU and FUDR aka Floxuridine are____ and cause___
Definition
antimetabolite (folic acid) cell cycle SPECIFIC... cause myelosuppression
Term
Client teaching about antimetabolite
Definition
darkening of veins, mucous membranes and fingernails may occur, PHOTOSENSITIVITY
Term
Tamoxifen (nolvadex)
Definition
antiestrogen; weight loss, thrombosis, hot flashes; tx tumor that depends on estrogen for growth; may cause stroke
Term
Medroxyprogesterone (Provera) *black box*
Definition
BLACK BOX WARNING: causes loss of bone density; agent for dysfunctional bleeding of uterine (depo-provera)
Term
testosterone
Definition
used for palliative tx in breast cancer for women; adverse effect of virilization;
Term
cell cycle non specific works on
Definition
DNA replication and RNA transcription
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