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Cancer Matching - Exam #5
Cancer drugs and mechanisms.
23
Pharmacology
Undergraduate 2
04/26/2015

Additional Pharmacology Flashcards

 


 

Cards

Term
Initiator
Definition
agent which stimulates clonal expansion or growth autonomy
Term
Complete Carcinogen
Definition
agent which can induce cancer in normal cells
Term
Promoter
Definition
agent which can cause permanent DNA changes
Term
Progressor
Definition
agent which induces invasiveness and metastatic ability
Term
Cisplatin, Busulfan
Definition
DNA crosslinking by covalently bridging guanine bases
Term
Paclitaxel, Vinblastine
Definition
inhibit microtubule function
Term
Hydroxyurea
Definition
inhibit deoxyribonucleotide synthesis
Term
Methotrexate, Pemetrexed
Definition
inhibit enzymes needed for DNA base synthesis
Term
Etoposide, Teniposide
Definition
increase DNA strand breakage by inhibiting repair enzymes
Term
Doxorubicin, Bleomycin
Definition
increase DNA strand breakage by inserting between DNA bases
Term
Pancreatic Cancer
Definition
cancer associated with the poorest survival rate
Term
Prostate Cancer
Definition
cancer with the highest incidence among males
Term
Breast Cancer
Definition
cancer with the highest incidence among females
Term
Lung Cancer
Definition
cancer with the greatest mortality among males
Term
Lung Cancer
Definition
cancer with the greatest mortality among females
Term
Stomach Cancer
Definition
cancer with declining incidence in the US for the past 60 years
Term
Irinotecan
Definition
Topoisomerase I inhibitor
Term
Etoposide
Definition
Topoisomerase II inhibitor
Term
Interferon-alpha
Definition
Antiviral used to treat hepatitis C and Kaposi’s sarcoma
Term
Il-2 (proleukin)
Definition
used to treat malignant melanoma
Term
Bicalutamide (Casodex)
Definition
anti-androgen used to treat prostate cancer
Term
Raloxifene (Evista)
Definition
anti-estrogen used to treat breast cancer
Term
Letrozole (Femara)
Definition
Aromatase inhibitor used to treat breast cancer
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