Term
|
Definition
Alkylating
cardiotoxicity
bladder burn - MESNA |
|
|
Term
|
Definition
Alkylating
neurotoxicity (central)
bladder burn - MESNA |
|
|
Term
|
Definition
Alkylating
carmustine-BBB
bone marrow depression
pulmonary fibrosis |
|
|
Term
|
Definition
alkylating
bone marrow depression |
|
|
Term
|
Definition
Alkylating
nephrotoxicity (hydration)
ototoxicity
peripheral neuropathy |
|
|
Term
|
Definition
anti-metabolite
inhibits dTMP
bone marrow depression
hepatic necrosis |
|
|
Term
|
Definition
|
|
Term
|
Definition
anti-metabolite
inhibits purine synthesis and causes strand breaks
tx: leukemia in kids
bone marrow depression |
|
|
Term
|
Definition
anti-metabolite
inhibits DNA elongation
bone marrow depression |
|
|
Term
|
Definition
antibiotics
topo II
cardiotoxicity
bone marrow depression |
|
|
Term
|
Definition
antibiotics
topo II
cardiotoxicity
bone marrow depression
drug interaction: cimetidine |
|
|
Term
|
Definition
antibiotic
topo II and RNAP
severe local tissue damage |
|
|
Term
|
Definition
antibiotic
free radical dna fragmentation
pulmonary toxicity
mild bone marrow depression |
|
|
Term
|
Definition
plant drugs
inhibit microtubule polymerization
sensory neuropathy
vincristine mild bm depressoin
vinblastine blasts bm |
|
|
Term
|
Definition
plant drug
freezes microtubules
sensory neuropathy |
|
|
Term
|
Definition
plant drug
topo II
sensory neuropathy
bone marrow depression |
|
|
Term
|
Definition
receptor inhibitor
estradiol
breast cancer
hot flashes |
|
|
Term
|
Definition
receptor inhibitor
bcr-abl tyr kinase
pdgf receptor
CML and CMML |
|
|
Term
|
Definition
receptor inhibitor
her 2
metastatic breast cancer
cardiomyopathy
infusion rxn |
|
|
Term
|
Definition
receptor inhibitor
her 1
colorectal cancer
severe infusion-related |
|
|
Term
|
Definition
receptor inhibitor
vegf (cardio)
colorectal
cardio,htn, proteinuria |
|
|
