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| rare form of cancer derived from the mesothelial cells that cover the interior surfaces of the chest and abdominal cavities. |
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| a dose that must be exceeded before cancer rates begin to rise. |
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| this assumes there is no cancer risk at lower doses followed by a dose-response relationship at higher doses. |
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| these inhibit immune function and are give to organ transplant patients to prevent rejection of transplanted organ. |
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| polycyclic aromatic hydrocarbon |
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Definition
| diverse group of compounds constructed from multiple, fused benzene rings. |
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| cantain a nitroso group (N=O) joined to a nitrogen atom. |
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| structurally diverse group of cancer-causing molecules produced by biological organisms, mainly microorganisms and plants. |
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| any substance that is capable of causing cancer only after it has been metabolically activated. |
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| the oxidation reaction of substances catalyzed by cytochrome P450 into carcinogens. |
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| 3-membered ring containing an oxygen atom covalently bonded to two carbon atoms. the two carbons are electron deficient so they react with atoms that are electron rich. |
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| converts normal cells to a precancerous state. |
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| carcinogens that cause gene damage, usually by binding to the DNA. |
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| enzyme that plays a key role in one of the cell's normal pathways for controlling cell proliferation. |
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| a population of cells derived from a single initial cell by successive rounds of cell division. |
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| a chemical that exerts either characteristics of an initiating factor or a promoting factor, but not both. |
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Definition
| agents exhibiting the potential to cause cancer |
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